Anti-Mouse CD4, mFluor 540 Clone: GK1.5流式抗体 (新品)
¥2,464.00
- 分子靶点:CD4
- 种属:小鼠 (Mouse)
- 标记:mFlour 540
- 亚型:Rat IgG2b, κ
- 克隆号:GK1.5
在售SKU, F2100408, 70-F2100408-25, 70-F2100408-100
描述
商品名 |
Anti-Mouse CD4, mFluor 540 (Clone:GK1.5)流式抗体检测试剂 |
---|---|
靶点 | |
标记 |
mFlour 540 |
仪器 |
适用405nm激光器的流式细胞仪 |
亚型 |
Rat IgG2b, κ |
克隆号 |
GK1.5 |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例

图 - 小鼠脾脏细胞Anti-Mouse CD4, mFluor 540(Clone: GK1.5) (F2100408) 以全部细胞进行分析。
分子信息
CD4 分子靶点信息概述
- 分子名:CD4, CD4 molecule
- 基因家族:CD molecules; V-set domain containing; C2-set domain containing
- 全称:CD4 antigen (p55); T-cell surface glycoprotein CD4
CD4 分子靶点综述
克隆号GK1.5单克隆抗体能与小鼠CD4反应。CD4抗原是属于免疫球蛋白超家族的55 kDa细胞表面I型膜糖蛋白 。CD4作为一种共受体,与T细胞受体(TCR)合作,与抗原呈递细胞(APC)的class II MHC分子相互作用。大多数胸腺细胞、大多数辅助性T细胞、NK-T细胞的一个亚群表达CD4 ,树突状细胞和巨噬细胞表达较少。CD4在T细胞的发育中起着重要作用,是成熟T细胞发挥最佳功能所必需的。克隆号GK1.5抗体已被证明与克隆号YTS 177和YTS 191竞争CD4的结合。
小鼠 Mouse Cd4 分子靶点信息
- 分子名:Cd4, CD4 antigen
- 别称:
- L3T4
- Ly-4
- lymphocyte antigen 4
- 基因序列:NCBI_Gene: 12504
- 蛋白序列:
小鼠 Mouse Cd4 靶点分子功能(预测)
Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).
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