Anti-Human CD4, PE(Clone:HIT4a) 流式抗体 检测试剂
¥616.00
- 分子靶点:CD4
- 种属:人 (Human)
- 标记:PE
- 亚型:Mouse IgG1, κ
- 克隆号:HIT4a
在售SKU, 70-F11004C02-20, 70-F11004C02-50, 70-F11004C02-100, F11004C02, 70-F11004C02-25, 70-F11004C02-100
描述
商品名 |
Anti-Human CD4, PE(Clone:HIT4a) 检测试剂 |
---|---|
靶点 | |
标记 |
PE |
仪器 |
适用488nm, 532nm, 561nm激光器的流式细胞仪 |
亚型 |
Mouse IgG1, κ |
克隆号 |
HIT4a |
推荐应用 |
流式检测 |
用量 |
5 μL /Test |
纯化 |
亲和层析 |
储存液 |
含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2) |
保存条件 |
2 - 8℃避光,切勿冻存 |
结果示例

图 - 人外周血染色Anti-Human CD4, PE(F11004C02) 的结果。以 FSC/SSC 中的淋巴细胞设门进行分析。
分子信息
CD4 分子靶点信息概述
- 分子名:CD4, CD4 molecule
- 基因家族:CD molecules; V-set domain containing; C2-set domain containing
- 全称:CD4 antigen (p55); T-cell surface glycoprotein CD4
CD4 分子靶点综述
CD4也称为T4,为55 kD的单链I型跨膜糖蛋白,表达于大部分胸腺细胞、T细胞亚群和单核/巨噬细胞。CD4作为免疫球蛋白超家族的一员,可识别与MHC II类分子结合的抗原,参与细胞-细胞互作、胸腺分化和信号传导。CD4是HIV的主要受体,可与HIV gp120结合。CD4与IL-16也有相互作用。
人 Human CD4 分子靶点信息
- 分子名:CD4, CD4 molecule
- 别称:
- cd4 antigen
- CD4 antigen (p55)
- CD4 receptor
- CD4mut
- IMD79
- OKT4D
- T-cell surface antigen T4/Leu-3
- T-cell surface glycoprotein CD4
- 基因序列:NCBI_Gene: 920
- 蛋白序列:UniProtKB: P01730
人 Human CD4靶点分子功能(预测)
Enables several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in several processes, including cellular response to cytokine stimulus; leukocyte differentiation; and positive regulation of intracellular signal transduction. Acts upstream of or within maintenance of protein location in cell. Located in external side of plasma membrane and membrane raft. Is integral component of plasma membrane. Implicated in immunodeficiency 79. Biomarker of COVID-19 and severe acute respiratory syndrome.