Anti-Human CD4, FITC (Clone:RPA-T4) (新品)

CD4 分子靶点信息概述

• 分子名：CD4, CD4 molecule
• 基因家族：CD molecules; V-set domain containing; C2-set domain containing
• 全称：CD4 antigen (p55); T-cell surface glycoprotein CD4

CD4 分子靶点综述

CD4也称为T4，为55 kD的单链I型跨膜糖蛋白，表达于大部分胸腺细胞、T细胞亚群和单核/巨噬细胞。CD4作为免疫球蛋白超家族的一员，可识别与MHC II类分子结合的抗原，参与细胞-细胞互作、胸腺分化和信号传导。CD4是HIV的主要受体，可与HIV gp120结合。CD4与IL-16也有相互作用。

人 Human CD4 分子靶点信息

• 分子名：CD4, CD4 molecule
• 别称：
  • cd4 antigen
  • CD4 antigen (p55)
  • CD4 receptor
  • CD4mut
  • IMD79
  • OKT4D
  • T-cell surface antigen T4/Leu-3
  • T-cell surface glycoprotein CD4
• 基因序列：NCBI_Gene: 920
• 蛋白序列：UniProtKB: P01730

人 Human CD4靶点分子功能（预测）

Enables several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in several processes, including cellular response to cytokine stimulus; leukocyte differentiation; and positive regulation of intracellular signal transduction. Acts upstream of or within maintenance of protein location in cell. Located in external side of plasma membrane and membrane raft. Is integral component of plasma membrane. Implicated in immunodeficiency 79. Biomarker of COVID-19 and severe acute respiratory syndrome.