Anti-Human CD27, PE (Clone: 09) 检测试剂

CD27 分子靶点信息概述

• 分子名：CD27, CD27 molecule
• 基因家族：Tumor necrosis factor receptor superfamily; CD molecules
• 别名：TNFRSF7
• 曾用名：S152; Tp55
• 全称：tumor necrosis factor receptor superfamily, member 7; CD27 antigen; T-cell activation antigen S152

CD27 分子靶点综述

CD27是TNF受体超家族的一员，在幼稚T细胞、记忆B细胞、NK细胞、造血干细胞（HSC）和祖细胞上结构性表达。CD27是一种在CD4+和CD8+T细胞上表达的跨膜磷酸糖蛋白，在T细胞活化时表达增加，并从细胞表面脱落，活化后形成可溶性CD27（sCD27）。

人 Human CD27 分子靶点信息

• 分子名：CD27, CD27 molecule
• 别称：
  • CD27 antigen
  • CD27L receptor
  • MGC20393
  • S152
  • S152. LPFS2
  • T cell activation antigen CD27
  • T cell activation antigen S152
  • T-cell activation antigen CD27
  • T14
  • TNFRSF7
  • Tp55
  • tumor necrosis factor receptor superfamily member 7
  • tumor necrosis factor receptor superfamily, member 7
• 基因序列：NCBI_Gene: 939
• 蛋白序列：UniProtKB: P26842

人 Human CD27靶点分子功能（预测）

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in extrinsic apoptotic signaling pathway and negative regulation of apoptotic process. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Implicated in lymphoproliferative syndrome 2.