Rat CXCL1/CINC-1 Standard (大鼠趋化因子 (C-X-C基序) 配体1 标准品)
¥280.00
因产品会迭代升级,具体实验步骤请按纸质版说明书操作
描述
文章目录[隐藏]
本产品只包含标准品试剂,如需购买试剂盒请点击下图
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- EK396
- ELISA试剂盒
Rat CXCL1/CINC-1 ELISA Kit 检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
商品名 |
Rat CXCL1/CINC-1 Standard (大鼠趋化因子 (C-X-C基序) 配体1 标准品) |
---|---|
组分 |
大鼠 CXCL1/CINC-1标准品 |
检测方法 |
双抗夹心法 |
样本类型 |
血清,血浆,细胞培养上清及其他生物学样本 |
板式 |
管 |
保存 |
短期4℃,长期-20℃保存 |
运输条件 |
4℃蓝冰运输 |
检测原理:本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗大鼠CXCL1抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的CXCL1与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中CXCL1的浓度成正比。加入终止液终止反应,在450 nm波长(参考波长570 - 630 nm)测定吸光度值。
分子信息
CXCL1 分子靶点信息概述
- 分子名:CXCL1, C-X-C motif chemokine ligand 1
- 基因家族:Chemokine ligands
- 别名:SCYB1; GROa; MGSA-a; NAP-3
- 曾用名:MGSA; GRO1; FSP
- 全称:melanoma growth stimulating activity, alpha; GRO1 oncogene (melanoma growth stimulating activity, alpha); fibroblast secretory protein; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL1 分子靶点综述
趋化因子(C-X-C基序)配体1(CXCL1)是一个小分子量细胞因子,属于CXC趋化因子家族,以前又被称为GRO1致癌基因、GROα、KC和中性粒细胞激活蛋白3 (NAP-3)。在人类中,该蛋白由CXCL1基因编码。CXCL1由人类黑色素瘤细胞分泌,具有促有丝分裂特性,且与黑色素瘤发病机制有关。CXCL1由巨噬细胞、中性粒细胞和上皮细胞表达,有中性粒细胞趋化活性。该趋化因子通过趋化因子受体CXCR2产生信号,进而引发它的作用效果。CXCL1通过抑制少突细胞前体的迁移,从而对脊髓发育起作用。它参与血管生长、炎症、伤口愈合和肿瘤发生过程。小鼠的初步研究表明,CXCL1可降低多发性硬化症的严重程度,可提供神经保护作用。
大鼠 Rat Cxcl1 分子靶点信息
- 分子名:Cxcl1, C-X-C motif chemokine ligand 1
- 别称:
- C-X-C motif chemokine 1
- chemokine (C-X-C motif) ligand 1
- chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
- CINC-1
- cytokine-induced neutrophil chemoattractant 1
- Gro
- Gro1
- growth-regulated alpha protein
- platelet-derived growth factor-inducible protein KC
- 基因序列:NCBI_Gene: 81503
- 蛋白序列:
大鼠 Rat Cxcl1 靶点分子功能(预测)
Enables chemokine activity. Involved in several processes, including neutrophil chemotaxis; positive regulation of ion transport; and response to amphetamine. Located in extracellular space. Biomarker of several diseases, including acute necrotizing pancreatitis; pneumonia (multiple); prostatitis; severe acute respiratory syndrome; and status epilepticus. Orthologous to human CXCL1 (C-X-C motif chemokine ligand 1); CXCL2 (C-X-C motif chemokine ligand 2); and CXCL3 (C-X-C motif chemokine ligand 3).
操作步骤
文章目录[隐藏]
- ELISA操作常见问题
- 血清OR血浆,哪个是ELISA的菜 
- ELISA通关必备丨数据篇丨标准曲线不佳 
- ELISA通关必备丨操作篇丨常见问题及解决方案 
- ELISA通关必备丨操作篇丨溶解与稀释标准品 
- ELISA通关必备丨样本篇丨不常见样本 
- ELISA通关必备丨样本篇丨常见样本丨细胞 
- ELISA通关必备丨如何选择试剂盒 
- ELISA通关必备丨基础知识 
- 真?假?ELISA试剂盒选择要小心 
- ELISA常见类型一 | 双抗夹心法,你要的都在这里! 
- ELISA常见类型二 | 竞争法,五分钟搞定! 
- 叮!联科向您投递了个ELISA实验操作干货包,请查收~ 
- 【视频】ELISA实验操作步骤演示视频教程 
- ELISA 组织样本的处理—大鼠组织 
- 【视频】ELISA实验原理与常见问题分析 
- 查看更多ELISA操作相关问题
ELISA操作常见问题
查看更多ELISA操作相关问题
引用文献
文章目录[隐藏]
- Pathogenic Functions of Tumor Necrosis Factor Receptor-Associated Factor 6 Signaling Following Traumatic Brain Injury 
- PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway 
- SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway 
- White adipose tissue, a novel antirheumatic target: Clues from its secretory capability and adipectomy-based therapy 
- An injectable antibacterial hydrogel to regulate ocular immune for endophthalmitis treatment 
- Vision Defense: Efficient Antibacterial AIEgens Induced Early Immune Response for Bacterial Endophthalmitis 
Pathogenic Functions of Tumor Necrosis Factor Receptor-Associated Factor 6 Signaling Following Traumatic Brain Injury 
PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway 
SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway 
White adipose tissue, a novel antirheumatic target: Clues from its secretory capability and adipectomy-based therapy 
An injectable antibacterial hydrogel to regulate ocular immune for endophthalmitis treatment 
- 眼球玻璃体
Vision Defense: Efficient Antibacterial AIEgens Induced Early Immune Response for Bacterial Endophthalmitis 
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