Mouse IL-3 Standard (小鼠白细胞介素3 (IL-3) 标准品)

IL3 分子靶点信息概述

• 分子名：IL3, interleukin 3
• 基因家族：Interleukins
• 别名：IL-3; MULTI-CSF; MCGF; MGC79398; MGC79399
• 全称：multilineage-colony-stimulating factor; hematopoietic growth factor; P-cell stimulating factor; mast-cell growth factor; colony-stimulating factor, multiple; interleukin 3 (colony-stimulating factor, multiple)

IL3 分子靶点综述

白细胞介素3(IL-3)在人类中由IL3基因编码。它是一种生物信号(细胞因子)，可作为免疫系统的一部分来提高机体对疾病的先天免疫应答。它是由嗜碱性粒细胞和活化的T细胞分泌产生，在免疫应答中可协助骨髓来源的T细胞生长和分化。IL-3通过结合IL-3受体起作用，可刺激多能造血干细胞分化为髓系祖细胞，或与IL-7一起，刺激多能造血干细胞分化为淋巴系祖细胞。另外，IL-3与其它细胞因子，如促红细胞生成素(EPO)、粒细胞巨噬细胞集落刺激因子(GM-CSF)和IL-6一起刺激髓系的所有细胞(粒细胞、单核细胞和树突状细胞)增殖。

小鼠 Mouse Il3 分子靶点信息

• 分子名：Il3, interleukin 3
• 别称：
  • BPA
  • colony stimulating factor, multi (contains Il-3)
  • Csfmu
  • HCGF
  • Il-3
  • MCGF
  • PSF
• 基因序列：NCBI_Gene: 16187
• 蛋白序列：
  • UniprotKB: P01586
  • UniprotKB: Q0PMN2
  • UniprotKB: Q5SX77

小鼠 Mouse Il3 靶点分子功能（预测）

Enables cytokine activity; growth factor activity; and interleukin-3 receptor binding activity. Acts upstream of or within several processes, including cell surface receptor signaling pathway; monocyte differentiation; and regulation of phosphate metabolic process. Located in extracellular space. Is expressed in skin; stomach; thymus; and vascular system. Human ortholog(s) of this gene implicated in Graves' disease; asthma; and rheumatoid arthritis. Orthologous to human IL3 (interleukin 3).