EK2130S

Mouse CCL11/Eotaxin Standard (小鼠 CCL11/Eotaxin 标准品)

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¥180.00

因产品会迭代升级,具体实验步骤请按纸质版说明书操作

  • 分子靶点:CCL11, Eotaxin, SCYA11
  • 种属:小鼠 (Mouse)
  • 试剂盒:EK2130
  • 保存:短期4℃保存,长期-20℃保存
  • 运输条件:4℃蓝冰运输

在售SKU:70-EK2130S


描述

本产品只包含标准品试剂,如需购买试剂盒请点击下图

商品名

Mouse CCL11/Eotaxin Standard (小鼠 CCL11/Eotaxin 标准品)

组分

小鼠CCL11/Eotaxin标准品

检测方法

双抗夹心法

样本类型

血清,血浆,细胞培养上清及其他生物学样本

板式

保存

短期4℃,长期-20℃保存

运输条件

4℃蓝冰运输

检测原理:本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗小鼠Eotaxin抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的Eotaxin与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中Eotaxin的浓度成正比。加入终止液终止反应,在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Mouse CCL11/Eotaxin ELISA Kit (小鼠 CCL11/Eotaxin ELISA试剂盒) - 标准曲线
标准曲线

分子信息

概述小鼠 CCL11, Eotaxin, SCYA11 靶点信息

CCL11 分子靶点信息概述

  • 分子名:CCL11, C-C motif chemokine ligand 11
  • 基因家族:Chemokine ligands
  • 别名:eotaxin; MGC22554
  • 曾用名:SCYA11
  • 全称:eotaxin-1; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); chemokine (C-C motif) ligand 11

CCL11 分子靶点综述

趋化因子配体11(CCL11)也称为嗜酸性粒细胞趋化因子(Eotaxin),是CC趋化因子家族中的小分子量细胞因子。Eotaxin通过诱导嗜酸性粒细胞的趋化性进行选择性招募,因此参与变态反应。Eotaxin在人和小鼠血浆中的表达升高与其衰老有关。相比于曾经吸食大麻者和从未吸食大麻者,目前仍在吸食大麻者的血浆中含有更高浓度的Eotaxin。精神分裂者体内的Eotaxin浓度也更高,而大麻正是已知的精神分裂症诱导剂。

小鼠 Mouse Ccl11 分子靶点信息

  • 分子名:Ccl11, chemokine (C-C motif) ligand 11
  • 别称:
    • eotaxin
    • Scya11
    • small inducible cytokine A11
  • 基因序列:NCBI_Gene: 20292
  • 蛋白序列:

小鼠 Mouse Ccl11 靶点分子功能(预测)

Predicted to enable CCR3 chemokine receptor binding activity; chemokine activity; and protein dimerization activity. Involved in several processes, including modulation of age-related behavioral decline; negative regulation of neurogenesis; and positive regulation of angiogenesis. Acts upstream of or within branching involved in mammary gland duct morphogenesis and mammary duct terminal end bud growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in embryo; endocardial lining; liver parenchyma; liver vasculature; and yolk sac blood vessel. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11).

操作步骤

ELISA操作常见问题

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引用文献

文章目录[隐藏]


  1. Eotaxin‑1 and MCP‑1 serve as circulating indicators in response to power frequency electromagnetic field exposure in mice 

  2. Skin Commensal Bacteria Modulates the Immune Balance of Mice to Alleviate Atopic Dermatitis-Induced Damage. 

  3. TMT-based quantitative proteomics reveals suppression of SLC3A2 and ATP1A3 expression contributes to the inhibitory role of acupuncture on airway inflammation in an OVA-induced mouse asthma model 

  4. Melatonin modulates airway smooth muscle cell phenotype by targeting the STAT3/Akt/GSK-3β pathway in experimental asthma 

  5. Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy 

  6. Therapeutic Effect of Renifolin F on Airway Allergy in an Ovalbumin-Induced Asthma Mouse Model In Vivo 

  7. High humidity aggravates the severity of arthritis in collagen-induced arthritis mice by upregulating xylitol and L-pyroglutamic acid 

  8. Protective Effects of Platycodin D3 on Airway Remodeling and Inflammation via Modulating MAPK/NF-κB Signaling Pathway in Asthma Mice 

  9. Lonicerin attenuates house dust mite-induced eosinophilic asthma through targeting Src/EGFR signaling 

  10. Celastrol alleviates atopic dermatitis by regulating Ezrin-mediated mitochondrial fission and fusion 

  11. Plumbagin alleviates obesity-related asthma: Targeting inflammation, oxidative stress, and the AMPK pathway 

  12. Effects of total alkaloids from Alstonia scholaris (L.) R. Br. on ovalbumin-induced asthma mice 

  13. Qi-fu-yin attenuated cognitive disorders in 5xFAD mice of Alzheimer's disease animal model by regulating immunity 

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