Human VEGF-C Standard (人血管内皮生长因子C 标准品)
¥280.00
描述
文章目录[隐藏]
本产品只包含标准品试剂,如需购买试剂盒请点击下图
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- EK1154
- ELISA试剂盒
Human VEGF-C ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
商品名 |
Human VEGF-C Standard (人血管内皮生长因子C 标准品) |
---|---|
组分 |
人VEGF-C冻干标准品 |
检测方法 |
双抗夹心法 |
样本类型 |
血清,血浆,细胞培养上清及其他生物学样本 |
板式 |
管 |
保存 |
短期4℃,长期-20℃保存 |
运输条件 |
4℃蓝冰运输 |
检测原理:本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人 VEGF-C 抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的 VEGF-C 与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物 TMB,避光显色。颜色反应的深浅与样本中 VEGF-C 的浓度成正比。加入终止液终止反应,在 450 nm 波长(参考波长 570 - 630 nm) 测定吸光度值。
分子信息
VEGFC 分子靶点信息概述
- 分子名:VEGFC, vascular endothelial growth factor C
- 基因家族:VEGF family
- 别名:VRP; VEGF-C
- 全称:vascular endothelial growth factor-related protein
VEGFC 分子靶点综述
血管内皮生长因子C(VEGF-C)是一种二聚体分泌型蛋白,PDGF/VEGF家族中的一员。翻译后的VEGF-C有三个结构域:中间的VEGF同源结构域(VHD)、N端结构域(前肽)和C端结构域(前肽)。VEGF-C对淋巴管的生成有重要作用,主要通过结合它的受体VEGFR-3来作用于淋巴管内皮细胞,从而促进其生存、生长和迁移。研究证明,VEGF-C是各种模型淋巴管的特定生长因子。VEGF-C除了对淋巴管有作用,它还可促进血管的生长并调节血管的通透性,是通过结合它的主要受体VEGFR-3或次级受体VEGFR-2来发挥作用的。另外,VEGF-C对神经发育和血压调节也具有重要作用。缺乏VEGF-C会导致淋巴水肿,而过量的VEGF-C与肿瘤血管生成和转移有关。
人 Human VEGFC 分子靶点信息
- 分子名:VEGFC, vascular endothelial growth factor C
- 别称:
- FLT4 ligand DHM
- Flt4-L
- LMPH1D
- LMPHM4
- vascular endothelial growth factor-related protein
- VEGF-C
- VRP
- 基因序列:NCBI_Gene: 7424
- 蛋白序列:UniProtKB: P49767
人 Human VEGFC靶点分子功能(预测)
Enables chemoattractant activity and vascular endothelial growth factor receptor 3 binding activity. Involved in induction of positive chemotaxis; positive regulation of mast cell chemotaxis; and vascular endothelial growth factor receptor signaling pathway. Predicted to be located in extracellular region and platelet alpha granule lumen. Predicted to be active in extracellular space. Implicated in breast carcinoma and hereditary lymphedema ID. Biomarker of several diseases, including invasive ductal carcinoma; liver disease (multiple); papillary carcinoma; pterygium; and urinary system cancer (multiple).
操作步骤
文章目录[隐藏]
- ELISA操作常见问题
- 血清OR血浆,哪个是ELISA的菜 
- ELISA通关必备丨数据篇丨标准曲线不佳 
- ELISA通关必备丨操作篇丨常见问题及解决方案 
- ELISA通关必备丨操作篇丨溶解与稀释标准品 
- ELISA通关必备丨样本篇丨不常见样本 
- ELISA通关必备丨样本篇丨常见样本丨细胞 
- ELISA通关必备丨如何选择试剂盒 
- ELISA通关必备丨基础知识 
- 真?假?ELISA试剂盒选择要小心 
- ELISA常见类型一 | 双抗夹心法,你要的都在这里! 
- ELISA常见类型二 | 竞争法,五分钟搞定! 
- 叮!联科向您投递了个ELISA实验操作干货包,请查收~ 
- 【视频】ELISA实验操作步骤演示视频教程 
- ELISA 组织样本的处理—大鼠组织 
- 【视频】ELISA实验原理与常见问题分析 
- 查看更多ELISA操作相关问题
ELISA操作常见问题
查看更多ELISA操作相关问题
引用文献
文章目录[隐藏]
- SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β‑catenin signaling pathway 
- Lin28/microRNA-let-7a promotes metastasis under circumstances of hyperactive Wnt signaling in esophageal squamous cell carcinoma 
- LncRNA-HNF1A-AS1 functions as a competing endogenous RNA to activate PI3K/AKT signalling pathway by sponging miR-30b-3p in gastric cancer 
- Synergistic effects of nanoattapulgite and hydroxyapatite on vascularization and bone formation in a rabbit tibia bone defect model 
- Cysteine protease inhibitor S promotes lymph node metastasis of esophageal cancer cells via VEGF-MAPK/ERK-MMP9/2 pathway 
- Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma 
- Targeting FAPα-positive lymph node metastatic tumor cells suppresses colorectal cancer metastasis 
SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β‑catenin signaling pathway 
Lin28/microRNA-let-7a promotes metastasis under circumstances of hyperactive Wnt signaling in esophageal squamous cell carcinoma 
LncRNA-HNF1A-AS1 functions as a competing endogenous RNA to activate PI3K/AKT signalling pathway by sponging miR-30b-3p in gastric cancer 
Synergistic effects of nanoattapulgite and hydroxyapatite on vascularization and bone formation in a rabbit tibia bone defect model 
Cysteine protease inhibitor S promotes lymph node metastasis of esophageal cancer cells via VEGF-MAPK/ERK-MMP9/2 pathway 
Neovascularization directed by CAVIN1/CCBE1/VEGFC confers TMZ-resistance in glioblastoma 
Targeting FAPα-positive lymph node metastatic tumor cells suppresses colorectal cancer metastasis 
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