EK189S
Human sICAM-1/CD54 Standard (人细胞间粘附分子1 (ICAM-1) 标准品)
¥180.00
因产品会迭代升级，具体实验步骤请按纸质版说明书操作
描述
文章目录[隐藏]
本产品只包含标准品试剂，如需购买试剂盒请点击下图
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- EK189
- ELISA试剂盒
Human sICAM-1/CD54 ELISA Kit检测试剂盒（酶联免疫吸附法）
- ¥1,600.00 – ¥2,650.00
| 商品名 |
Human sICAM-1/CD54 Standard (人细胞间粘附分子1 (ICAM-1) 标准品) |
|---|---|
| 组分 |
人细胞间粘附分子1 (ICAM-1)标准品 |
| 检测方法 |
双抗夹心法 |
| 样本类型 |
血清，血浆，细胞培养上清及其他生物学样本 |
| 板式 |
管 |
| 保存 |
短期4℃，长期-20℃保存 |
| 运输条件 |
4℃蓝冰运输 |
检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人sICAM-1抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的sICAM-1与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中sICAM-1的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。
分子信息
概述人 ICAM1, BB2, CD54 靶点信息
ICAM1 分子靶点信息概述
- 分子名：ICAM1, intercellular adhesion molecule 1
- 基因家族：CD molecules; Receptor ligands; Immunoglobulin like domain containing; Ig-like cell adhesion molecule family
- 别名：BB2; CD54
- 全称：human rhinovirus receptor
ICAM1 分子靶点综述
细胞间粘附分子1(ICAM-1)也称为CD54，是一个几乎无所不在的跨膜糖蛋白，通常表达于内皮细胞和免疫细胞，对白细胞迁移和活化具有关键作用。它与CD11a/CD18或CD11b/CD18型整合素结合，也会被鼻病毒作为受体利用。可溶性细胞间粘附分子1(sICAM-1)促进血管生成，可作为血管内皮细胞活化或受损的指示剂。它也可作为跨膜ICAM-1抑制剂，介导活性如单核细胞对活化的内皮细胞的黏附以及肿瘤细胞对NK细胞介导的溶解作用的敏感性。监测血清中的sICAM-1表达水平可对多种病理状态提供更加详细的视角，如心血管疾病、II型糖尿病、器官移植障碍、氧化应激、腹部脂肪团、高血压、肝脏疾病和某些恶性肿瘤等。
人 Human ICAM1 分子靶点信息
- 分子名：ICAM1, intercellular adhesion molecule 1
- 别称：
- BB2
- CD54
- cell surface glycoprotein P3.58
- human rhinovirus receptor
- ICAM-1
- intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
- major group rhinovirus receptor
- P3.58
- 基因序列：NCBI_Gene: 3383
- 蛋白序列：UniProtKB: P05362
人 Human ICAM1靶点分子功能（预测）
Enables integrin binding activity. Involved in several processes, including T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; cellular response to amyloid-beta; and negative regulation of apoptotic process. Located in extracellular exosome. Implicated in several diseases, including autoimmune disease (multiple); biliary atresia; diabetic retinopathy; inflammatory bowel disease (multiple); and liver cirrhosis. Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); diabetes mellitus (multiple); hematologic cancer (multiple); and lung disease (multiple).
操作步骤
文章目录[隐藏]
- ELISA操作常见问题
- 血清OR血浆，哪个是ELISA的菜
- ELISA通关必备丨数据篇丨标准曲线不佳
- ELISA通关必备丨操作篇丨常见问题及解决方案
- ELISA通关必备丨操作篇丨溶解与稀释标准品
- ELISA通关必备丨样本篇丨不常见样本
- ELISA通关必备丨样本篇丨常见样本丨细胞
- ELISA通关必备丨如何选择试剂盒
- ELISA通关必备丨基础知识
- 真？假？ELISA试剂盒选择要小心
- ELISA常见类型一 | 双抗夹心法，你要的都在这里！
- ELISA常见类型二 | 竞争法，五分钟搞定！
- 叮！联科向您投递了个ELISA实验操作干货包，请查收~
- 【视频】ELISA实验操作步骤演示视频教程
- ELISA 组织样本的处理—大鼠组织
- 【视频】ELISA实验原理与常见问题分析
- 查看更多ELISA操作相关问题
ELISA操作常见问题
查看更多ELISA操作相关问题
引用文献
文章目录[隐藏]
- Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways
- Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway
- miR-374b-5p is increased in deep vein thrombosis and negatively targets IL-10
- Plasma exosomal miRNAs involved in endothelial injury in microscopic polyangiitis patients
- Comprehensive Analysis of NAFLD and the Therapeutic Target Identified
- HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
- Simplified Gambogic Acid Prodrug Nanoparticles to Improve Efficiency and Reduce Toxicity for Clinical Translation Potential
- Procyanidin B2 alleviates oxidized low-density lipoprotein-induced cell injury, inflammation, monocyte chemotaxis, and oxidative stress by inhibiting the nuclear factor kappa-B pathway in human umbilical vein endothelial cells
- LncRNA MALAT1 suppresses monocyte-endothelial cell interactions by targeting miR-30b-5p and enhancing ATG5-mediated autophagy
- The Potential of Bioactive Fish Collagen Oligopeptides against Hydrogen Peroxide-Induced NIH/3T3 and HUVEC Damage: The Involvement of the Mitochondria
- A dual-targeting therapeutic nanobubble for imaging-guided atherosclerosis treatment
- Beneficial Effects of Small-Molecule Oligopeptides Isolated from Panax Ginseng C. A. Meyer on Cellular Fates in Oxidative Stress-Induced Damaged Human Umbilical Vein Endothelial Cells and PC-12
- Innate immune responsive inflammation in development of progressive myopia
- Long-term abuse of caffeine sodium benzoate induces endothelial cells injury and leads to coagulation dysfunction
- miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis
- 5-epi-ent-Kaurane diterpenoids from the aerial parts of Isodon eriocalyx and their anti-atherosclerotic potential
- Acteoside alleviates asthma by modulating ROS-responsive NF-κB/MAPK signaling pathway
- Associations of Serological Biomarkers of Sicam-1, Il-1β, Mif, and Su-Par with 3-Month Mortality in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
- Serum vimentin predicts mortality in pediatric severe sepsis: A prospective observational study
- Metabolic Profiling in Association with Vascular Endothelial Cell Dysfunction Following Non-Toxic Cadmium Exposure
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways
Cimifugin ameliorates imiquimod-induced psoriasis by inhibiting oxidative stress and inflammation via NF-κB/MAPK pathway
miR-374b-5p is increased in deep vein thrombosis and negatively targets IL-10
Plasma exosomal miRNAs involved in endothelial injury in microscopic polyangiitis patients
Comprehensive Analysis of NAFLD and the Therapeutic Target Identified
HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury
Simplified Gambogic Acid Prodrug Nanoparticles to Improve Efficiency and Reduce Toxicity for Clinical Translation Potential
Procyanidin B2 alleviates oxidized low-density lipoprotein-induced cell injury, inflammation, monocyte chemotaxis, and oxidative stress by inhibiting the nuclear factor kappa-B pathway in human umbilical vein endothelial cells
LncRNA MALAT1 suppresses monocyte-endothelial cell interactions by targeting miR-30b-5p and enhancing ATG5-mediated autophagy
The Potential of Bioactive Fish Collagen Oligopeptides against Hydrogen Peroxide-Induced NIH/3T3 and HUVEC Damage: The Involvement of the Mitochondria
A dual-targeting therapeutic nanobubble for imaging-guided atherosclerosis treatment
Beneficial Effects of Small-Molecule Oligopeptides Isolated from Panax Ginseng C. A. Meyer on Cellular Fates in Oxidative Stress-Induced Damaged Human Umbilical Vein Endothelial Cells and PC-12
Innate immune responsive inflammation in development of progressive myopia
Long-term abuse of caffeine sodium benzoate induces endothelial cells injury and leads to coagulation dysfunction
miR-147a targets ZEB2 to regulate ox-LDL-induced monocyte adherence to HUVECs, atherosclerotic plaque formation, and stability in atherosclerosis
5-epi-ent-Kaurane diterpenoids from the aerial parts of Isodon eriocalyx and their anti-atherosclerotic potential
Acteoside alleviates asthma by modulating ROS-responsive NF-κB/MAPK signaling pathway
- 血清
Associations of Serological Biomarkers of Sicam-1, Il-1β, Mif, and Su-Par with 3-Month Mortality in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
- 血清
Serum vimentin predicts mortality in pediatric severe sepsis: A prospective observational study
Metabolic Profiling in Association with Vascular Endothelial Cell Dysfunction Following Non-Toxic Cadmium Exposure
成为第一个“Human sICAM-1/CD54 Standard (人细胞间粘附分子1 (ICAM-1) 标准品)” 的评价者
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