CS0003
Brefeldin A（BFA）布雷非德菌素A
¥460.00
在售SKU:70-CS0003,CS0003
描述
1.产品简介
布雷非德菌素A (Brefeldin A, BFA)是一种胞内蛋白转运抑制剂。培养细胞加入BFA会阻断蛋白向高尔基体复合物(GC)转运，使之在内质网(ER)中积累。在细胞体外活化的最后几个小时加入BFA可增强胞内细胞因子的检测。BFA对大部分小鼠和人类胞内细胞因子的阻断有效。BFA的推荐工作浓度是2 - 20 μg/ml，但需要研究者对实验条件和效果进行优化和判断。
2.产品特点
•转运抑制能力强
•操作简单
•常备现货
引用文献统计
该产品被引用的文献总数为：31
- Bacteroides thetaiotaomicron relieves colon inflammation by activating aryl hydrocarbon receptor and modulating CD4+T cell homeostasis
影响因子：3.943刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：2020/11/20 - Sodium Butyrate Ameliorates Streptozotocin-Induced Type 1 Diabetes in Mice by Inhibiting the HMGB1 Expression
影响因子：3.519刊物：Frontiers in Endocrinology发表日期：2018/10/25 - Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease
影响因子：7.133刊物：Cell and Bioscience发表日期：2021/7/28 - Natural killer T cell/IL-4 signaling promotes bone marrow-derived fibroblast activation and M2 macrophage-to-myofibroblast transition in renal fibrosis
影响因子：4.932刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：2021/7/6 - Exosomal Vaccine Loading T Cell Epitope Peptides of SARS-CoV-2 Induces Robust CD8+ T Cell Response in HLA-A Transgenic Mice
影响因子：7.033刊物：International Journal of Nanomedicine发表日期：2022/7/29 - Schistosoma japonicum peptide SJMHE1 inhibits acute and chronic colitis induced by dextran sulfate sodium in mice
影响因子：3.876刊物：Parasites & Vectors发表日期：2021/9/6 - Role of TLR5 in the Translocation and Dissemination of Commensal Bacteria in the Intestine after Traumatic Hemorrhagic Shock
影响因子：4.818刊物：Journal of Immunology Research发表日期：2021/11/19 - Collagen I enhances the efficiency and anti-tumor activity of dendritic-tumor fusion cells
影响因子：7.719刊物：OncoImmunology发表日期：2017/9/6 - Recombinant KRAS G12D Protein Vaccines Elicit Significant Anti-Tumor Effects in Mouse CT26 Tumor Models
影响因子：4.848刊物：Frontiers in Oncology发表日期：2020/8/12 - Impaired granzyme B-producing regulatory B cells in systemic lupus erythematosus
影响因子：4.407刊物：MOLECULAR IMMUNOLOGY发表日期：2021/11/5 - FasL-PDPK1 Pathway Promotes the Cytotoxicity of CD8+ T Cells During Ischemic Stroke
影响因子：5.78刊物：Translational Stroke Research发表日期：2020/2/8 - Colorectal Cancer Progression Is Associated with Accumulation of Th17 Lymphocytes in Tumor Tissues and Increased Serum Levels of Interleukin-6
影响因子：1.283刊物：TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE发表日期：2014/7/2 - Probiotics alleviate adipose inflammation in high-fat diet–induced obesity by restoring adipose invariant natural killer T cells
影响因子：4.008刊物：NUTRITION发表日期：2021/4/25 - Polysaccharide from Radix Codonopsis has beneficial effects on the maintenance of T-cell balance in mice
影响因子：3.743刊物：BIOMEDICINE & PHARMACOTHERAPY发表日期：2019/2/20 - Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines
影响因子：1.692刊物：Molecular Medicine Reports发表日期：2017/9/25 - Exposure to biomass smoke induces pulmonary Th17 cell differentiation by activating TLR2 on dendritic cells in a COPD rat model
影响因子：4.374刊物：TOXICOLOGY LETTERS发表日期：2021/5/28 - Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway
影响因子：3.545刊物：MEDIATORS OF INFLAMMATION发表日期：2019/1/17 - Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model
影响因子：3.232刊物：MEDIATORS OF INFLAMMATION发表日期：2017/1/15 - Ethanol extract of Pycnoporus sanguineus relieves the dextran sulfate sodium-induced experimental colitis by suppressing helper T cell-mediated inflammation via apoptosis induction
影响因子：4.545刊物：BIOMEDICINE & PHARMACOTHERAPY发表日期：2020/5/11 - Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo
影响因子：2.806刊物：PLoS One发表日期：2017/5/8 - Fractalkine mediates lymphocyte inflammation and tubulointerstitial lesions by modifying the Treg/Th17 balance in lupus-prone MRL/lpr mice
影响因子：3.375刊物：American Journal of Translational Research发表日期：2020/10/15 - Impairment of Granzyme B-Producing Regulatory B Cells Correlates with Exacerbated Rheumatoid Arthritis
影响因子：6.429刊物：Frontiers in Immunology发表日期：2017/6/30 - Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study
影响因子：12.121刊物：Nature Communications发表日期：2020/4/20 - Abnormal expression of b10 cell frequencies: possible relation to pathogenesis and disease severity of aplastic anemia
影响因子：0.801刊物：Revista da Associacao Medica Brasileira发表日期：2019/6/3 - Correlation of gammadelta-T-cells, Th17 cells and IL-17 in peripheral blood of patients with allergic rhinitis.
影响因子：1.255刊物：ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY发表日期：2014/9/1 - MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease
影响因子：3.384刊物：BRITISH JOURNAL OF OPHTHALMOLOGY发表日期：2018/2/1 - Dual roles of CD11b+CD33+HLA-DR-/lowCD14- myeloid-derived suppressor cells with a granulocytic morphology following allogeneic hematopoietic stem cell transplantation: from inflammation promoters to immune suppressors within 90 days
影响因子：5.7刊物：Frontiers in Immunology发表日期：2024-07-08 - Ginkgolic acids induce liver injury in mice through cell cycle arrest and immune stress under specific condition
影响因子：2.6刊物：TOXICON发表日期：2024-05-30 - Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice
影响因子：4.3刊物：Stem Cells International发表日期：2023-10-17 - Impaired regulatory function of granzyme B-producing B cells against T cell inflammatory responses in lupus mice
影响因子：3.9刊物：Lupus Science & Medicine发表日期：2023-07-01 - Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses
刊物：Expert Opin Ther Targets. 2021 Nov;25(11):1017-1024.
刺激阻断剂操作常见问题查看更多刺激阻断剂操作步骤技术文章
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引用文献
1
Cui Donghua, Zhang Lili, Chen Jiaxi et al. Changes in regulatory B cells and their relationship with rheumatoid arthritis disease activity[J]. Clinical and Experimental Medicine, 2015, 15(3): 285-292 (IF:2.959)
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2
Chen Y, Yu M, Liu X, et al. Clinical characteristics and peripheral T cell subsets in Parkinson's disease patients with constipation[J]. Int J Clin Exp Pathol, 2015, 8(3): 2495-2504 (IF:2.168)
查看原文
3
Cheng C, Deng L, Li R. The Immunogenicity and Anti-Tumor Efficacy of a Rationally Designed EGFR Vaccine[J]. Cellular Physiology and Biochemistry, 2018, 46: 46-56 (IF:3.923)
查看原文
4
Weihong Wang, Zhaowei Tong, Jianfeng Zhong, et al. Identification of IL-10-secreting CD8+CD28?PD-1+ regulatory T cells associated with chronic hepatitis C virus infection[J]. Immunology Letters, 2018, 202: 16-22 (IF:2.436)
查看原文
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