Anti-Human CD79a, PE (Clone: HM47) (新品)

CD79A 分子靶点信息概述

• 分子名：CD79A, CD79a molecule
• 基因家族：CD molecules; V-set domain containing
• 别名：MB-1
• 曾用名：IGA
• 全称：B-cell antigen receptor complex-associated protein alpha chain; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha

CD79A 分子靶点综述

CD79a 又称 mb-1，是一种 47kDa 膜糖蛋白，与 CD79b 结合形成异二聚体 B 细胞受体(BCR)。这种受体负责 B 细胞信号传导，导致激活、凋亡或过敏。从最早的B 细胞到浆细胞，CD79a 的表达一直存在。CD79 表达于 B 细胞肿瘤和一些非 B 细胞恶性肿瘤，如 AML。与其它可以在 B 细胞肿瘤细胞中表达的抗体不同，HM47 是识别 CD79a 的可靠抗体，因此是 B 细胞的良好标记。由于 CD79a 的几个变体存在，表位的确切位置可能略有不同。

人 Human CD79A 分子靶点信息

• 分子名：CD79A, CD79a molecule
• 别称：
  • B-cell antigen receptor complex-associated protein alpha chain
  • CD79a antigen (immunoglobulin-associated alpha)
  • CD79a molecule, immunoglobulin-associated alpha
  • ig-alpha
  • IGA
  • MB-1
  • MB-1 membrane glycoprotein
  • membrane-bound immunoglobulin-associated protein
  • surface IgM-associated protein
• 基因序列：NCBI_Gene: 973
• 蛋白序列：UniProtKB: P11912

人 Human CD79A靶点分子功能（预测）

Enables identical protein binding activity. Predicted to be involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Predicted to be located in membrane raft and multivesicular body. Predicted to be part of B cell receptor complex. Predicted to be active in external side of plasma membrane. Implicated in agammaglobulinemia.