Anti-Human CD55, PE (Clone: JS11) (新品)

CD55 分子靶点信息概述

• 分子名：CD55, CD55 molecule (Cromer blood group)
• 基因家族：Blood group antigens; CD molecules; Sushi domain containing; Complement system regulators and receptors
• 别名：CR; TC; CROM
• 曾用名：DAF
• 全称：decay accelerating factor for complement (CD55, Cromer blood group system); CD55 molecule, decay accelerating factor for complement (Cromer blood group)

CD55 分子靶点综述

CD55 是一种 60-70kD 的糖基磷脂酰肌醇(GPI)固定单链糖蛋白，又称衰变加速因子(DAF)。它表达于造血细胞，包括红细胞和许多非造血细胞。CD55 可降低 NK 细胞裂解效率，诱导 T 细胞信号转导。CD55 还被证明与 CD97 相互作用，并与柯萨奇和呼肠孤病毒结合。

人 Human CD55 分子靶点信息

• 分子名：CD55, CD55 molecule (Cromer blood group)
• 别称：
  • CD55 antigen
  • CD55 molecule, decay accelerating factor for complement (Cromer blood group)
  • CHAPLE
  • complement decay-accelerating factor
  • CR
  • CROM
  • Cromer blood group antigen
  • DAF
  • decay accelerating factor for complement
  • Rh blood group D antigen
  • TC
• 基因序列：NCBI_Gene: 1604
• 蛋白序列：UniProtKB: P08174

人 Human CD55靶点分子功能（预测）

Enables lipid binding activity and virus receptor activity. Involved in several processes, including positive regulation of CD4-positive, alpha-beta T cell proliferation; positive regulation of T cell cytokine production; and regulation of lipopolysaccharide-mediated signaling pathway. Acts upstream of or within regulation of complement activation and regulation of complement-dependent cytotoxicity. Located in cell surface; membrane raft; and plasma membrane. Implicated in prostate cancer and protein-losing enteropathy. Biomarker of breast cancer; cervical cancer; and endometrial adenocarcinoma.