日前，汤森路透首次发布了前沿研究、科研管理与科学政策制定的相关报告：《2013研究前沿：科学与社科领域的百强研究》（Research Fronts 2013: 100 Top Ranked Specialties in the Sciences and Social Sciences）。报告中列出了当前十大前沿研究领域，以及每个领域中排名前十的重点研究。这次公布的研究，也可能成为2013年度科学与社科领域的重点。
该报告对2007年至2012年高引用率的研究论文，以及发表在核心期刊和基础期刊上的文章进行分析后发现，科学与社会科学领域的前沿研究主要涉及以下十大领域：
农业、植物与动物科学（Agriculture, Plant and Animal Sciences）
生态学与环境科学（Ecology and Environmental Sciences）
地球科学（Geosciences）
临床医学（Clinical Medicine）
生物科学（Biological Sciences）
化学与材料科学（Chemistry and Materials Science）
物理学（Physics）
天文学与天体物理学（Astronomy and Astrophysics）
数学、计算科学与工程学（Mathematics, Computer Science and Engineering）
经济学、心理学和其他社会科学（Economics, Psychology and Other Social Sciences）
研究人员表示，对科研领域进行趋势分析能让研究人员、科研资助者和机构管理人员对当前的科研发展有一个整体认识，帮助他们在科研精力投入、科研资金和资源分配等方面做出更好的决策。
生物科学（Biological Sciences）领域中排名前十的重点研究如下：
| RANK | research fronts | core papers |
citations | mean year of core papers |
| 1 | DNA methylation analysis and missing heritability | 25 | 3,153 | 2011 |
| 2 | Toxicity of amyloid beta (Aβ) oligomers in Alzheimer’s disease | 45 | 2,588 | 2010.6 |
| 3 | Differentiation and function of follicular helper CD4 T cells (TFH) | 38 | 2760 | 2010.5 |
| 4 | Human beta(2) adrenergic G-protein-coupled receptors (GPCRs) | 44 | 6261 | 2010.4 |
| 5 | Linear ubiquitin chain assembly complex and activation of nuclear factor-κB (NF-κB) | 43 | 3,749 | 2010.4 |
| 6 | Lgr5 receptor-expressing intestinal stem cells | 23 | 2,699 | 2010.3 |
| 7 | TET mutations, reduction of 5-hydroxymethylcytosine (5hmC), and malignancy | 45 | 6,112 | 2010.2 |
| 8 | Inhibition of TO R (Target Of Rapamycin) signaling, increased lifespan, and diseases of aging |
30 | 3,152 | 2010.1 |
| 9 | HIV-1 Vpu and Vpx proteins and restriction factors SAMHD1 and BST -2/Tetherin | 48 | 3,760 | 2009.9 |
| 10 | Mitochondrial sirtuins and regulation of metabolism | 32 | 3,395 | 2009.9 |
农业、植物与动物科学（Agriculture, Plant and Animal Sciences）领域中排名前十的重点研究如下：
位列三甲的分别为： DNA甲基化与丢失遗传性研究、阿尔茨海默症的β淀粉样蛋白（Aβ）、滤泡辅助性CD4 T细胞（TFH）的分化和功能。
|
RANK |
research fronts |
core |
citations |
mean year of |
|
1 |
Impact of climate change on food crops |
32 |
1537 |
2010 |
|
2 |
Comprehensive classification of fungi based on molecular evolutionary analysis |
18 |
1374 |
2010 |
|
3 |
Arabidopsis chloroplast RnA editing |
46 |
2578 |
2009.9 |
|
4 |
Jasmonate biosynthesis and signaling |
33 |
2548 |
2009.9 |
|
5 |
oomycete RXlR effectors and suppression of plant immunity |
47 |
2340 |
2009.7 |
|
6 |
Angiosperm phylogeny group classification |
34 |
2259 |
2009.7 |
|
7 |
methicillin-resistant Staphylococcus aureus (mRsA) in livestock |
17 |
1071 |
2009.7 |
|
8 |
genomic selection and estimated breeding values |
39 |
2281 |
2009.6 |
|
9 |
honey bee colony collapse disorder and Nosema ceranae |
30 |
1718 |
2009.6 |
|
10 |
insect resistance to transgenic crops producing bt (Bacillus thuringiensis) toxins for pest control |
22 |
1134 |
2009.6 |
生态学与环境科学（Ecology and Environmental Sciences）领域中排名前十的重点研究如下：
|
RANK |
research fronts |
core |
citations |
mean year of |
|
1 |
ocean acidification and marine ecosystems |
45 |
3653 |
2009.6 |
|
2 |
biodiversity and functional ecosystems |
43 |
3139 |
2009.5 |
|
3 |
mangrove forests and climate change |
16 |
1121 |
2009.5 |
|
4 |
models and impacts of land-use change |
18 |
2318 |
2009.4 |
|
5 |
biochar amendment techniques and effects |
41 |
2300 |
2009.4 |
|
6 |
Adaptive evolution in invasive species and approximate bayesian computation |
19 |
1255 |
2009.4 |
|
7 |
Chytridiomycosis and large-scale amphibian population extinctions |
13 |
1003 |
2009.3 |
|
8 |
Pharmaceutical residues in environmental water and wastewater |
50 |
3815 |
2009.1 |
|
9 |
Community ecology and phylogenetic comparative biology |
20 |
1,799 |
2009.1 |
|
10 |
Climate warming, altered thermal niches, and species impact |
14 |
1,244 |
2009.1 |
临床医学（Clinical Medicine）领域中排名前十的重点研究如下：
|
RANK |
research fronts |
core |
citations |
mean year of |
|
1 |
transcatheter aortic valve implantation |
50 |
2818 |
2011 |
|
2 |
Atypical hemolytic uremic syndrome and complement activation |
36 |
1939 |
2010.6 |
|
3 |
Acquired bRAf inhibitor resistance in metastatic melanoma |
36 |
4777 |
2010.5 |
|
4 |
idiopathic pulmonary fibrosis and randomized placebo-controlled drug trials |
38 |
2269 |
2010.5 |
|
5 |
Pathology and treatment of nonalcoholic fatty liver disease |
34 |
1978 |
2010.5 |
|
6 |
Chemotherapy with and without bevacizumab for heR2-negative breast cancer |
14 |
1909 |
2010.5 |
|
7 |
brentuximab vedotin for refractory and relapsed hodgkin’s lymphoma |
23 |
2001 |
2010.4 |
|
8 |
il28b polymorphisms and treatment response in hepatitis C patients |
47 |
5172 |
2010.3 |
|
9 |
Anaplastic lymphoma kinase (AlK) inhibition in non-small cell lung cancer |
46 |
3716 |
2010.3 |
|
10 |
global, national, and regional assessments of maternal, newborn, and child health |
42 |
2640 |
2010.3 |
