THY1 靶点信息

THY1 分子靶点信息概述

  • 分子名：THY1, Thy-1 cell surface antigen
  • 基因家族：Ig-like cell adhesion molecule family; CD molecules; Immunoglobulin like domain containing
  • 别名：CD90

THY1/CD90 分子靶点综述

CD90（Thy 1）抗原是免疫球蛋白超家族的GPI连接的糖蛋白成员。CD90在小鼠T细胞、胸腺细胞、神经细胞、库普弗细胞和成纤维细胞中表达。CD90可能在脑内突触发生的细胞与细胞或细胞与配体相互作用中发挥作用。CD90可作为多种干细胞和成熟神经元轴突过程的标记物。CD90的结构研究导致了免疫球蛋白超家族的建立，它是其中最小的成员，并导致了脊椎动物GPI锚的首次生化描述和表征。

THY1, Thy-1 cell surface antigen 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human THY1/CD90 分子靶点信息

人 Human CD90靶点分子功能（预测）

Enables integrin binding activity. Involved in integrin-mediated signaling pathway; positive regulation of cell adhesion; and positive regulation of cellular extravasation. Located in apical plasma membrane; cell surface; and endoplasmic reticulum.

小鼠 Mouse Thy1 分子靶点信息

小鼠 Mouse Ager 靶点分子功能（预测）

Enables integrin binding activity. Involved in several processes, including integrin-mediated signaling pathway; positive regulation of focal adhesion assembly; and retinal cone cell development. Located in dendrite; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; appendicular skeleton; nervous system; retina; and urinary system. Orthologous to human THY1 (Thy-1 cell surface antigen).

大鼠 Rat Thy1 分子靶点信息

  • 分子名：Thy1, Thy-1 cell surface antigen
  • 别称：
    • CD7
    • CD90
    • thy-1 antigen
    • thy-1 glycoprotein
    • Thy-1 membrane glycoprotein
    • Thy-1 protein
    • thymus cell antigen 1, theta
    • Thymus cell surface antigen
  • 基因序列：NCBI_Gene: 24832
  • 蛋白序列：

大鼠 Rat Thy1 靶点分子功能（预测）

Enables GPI anchor binding activity; GTPase activator activity; and protein kinase binding activity. Involved in several processes, including T cell receptor signaling pathway; focal adhesion assembly; and negative regulation of neuron projection development. Located in several cellular components, including growth cone; neuron projection membrane; and neuronal cell body membrane. Biomarker of retinal disease and retinal ischemia. Orthologous to human THY1 (Thy-1 cell surface antigen).

CD90/THY1 分子产品列表

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