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MMP10 分子靶点信息概述
- 分子名:MMP10, matrix metallopeptidase 10
- 基因家族:M10 matrix metallopeptidases
- 曾用名:STMY2
- 全称:matrix metalloproteinase 10 (stromelysin 2); stromelysin 2
MMP10 分子靶点综述
基质金属蛋白酶 10 (MMP-10),又名基质溶素-2,在人类中由 MMP10 基因编码。该基因是位 于染色体 11q 22.3 的 MMP 基因簇的一部分,MMP-10 降解蛋白聚糖和纤连蛋白,在各种病理条件 下的细胞外基质降解中起重要作用。MMP-10 在破骨细胞和骨髓内的多数单核细胞中强烈表达,在人角质形成细胞中受细胞因子诱导,同样也在人的头颈癌和肺癌细胞中表达。糖尿病患者角膜上皮中过表达的 MMP-10 可能是 糖尿病性视网膜病变的主要因素。MMP-10 与肿瘤干细胞的活力及转移有关。
MMP10, matrix metallopeptidase 10 分子靶点种属信息
人 Human MMP10 分子靶点信息
- 分子名:MMP10, matrix metallopeptidase 10
- 别称:
- matrix metalloprotease 10
- matrix metalloproteinase 10 (stromelysin 2)
- matrix metalloproteinase-10
- MMP-10
- SL-2
- STMY2
- stromelysin 2
- stromelysin-2
- transin 2
- transin-2
- 基因序列:NCBI_Gene: 4319
- 蛋白序列:UniProtKB: P09238
人 Human MMP10靶点分子功能(预测)
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to act upstream of or within regulation of cell migration. Predicted to be located in extracellular space. Biomarker of adrenoleukodystrophy; diabetes mellitus; and end stage renal disease.
小鼠 Mouse Mmp10 分子靶点信息
- 分子名:Mmp10, matrix metallopeptidase 10
- 别称:
- AV377895
- expressed sequence AV377895
- stromelysin 2
- 基因序列:NCBI_Gene: 17384
- 蛋白序列:
小鼠 Mouse Mmp10 靶点分子功能(预测)
Predicted to enable metalloendopeptidase activity. Acts upstream of or within regulation of cell migration. Predicted to be located in extracellular matrix and extracellular region. Is expressed in gonad; ovary; and testis. Orthologous to human MMP10 (matrix metallopeptidase 10).
大鼠 Rat Mmp10 分子靶点信息
- 分子名:Mmp10, matrix metallopeptidase 10
- 别称:
- matrix metallopeptidase 10 (stromelysin 2)
- matrix metalloproteinase 10
- matrix metalloproteinase-10
- MMP-10
- SL-2
- stromelysin 2
- stromelysin-2
- transformation-associated protein 34A
- transin-2
- 基因序列:NCBI_Gene: 117061
- 蛋白序列:
大鼠 Rat Mmp10 靶点分子功能(预测)
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to act upstream of or within regulation of cell migration. Predicted to be located in extracellular matrix and extracellular region. Orthologous to human MMP10 (matrix metallopeptidase 10).
MMP10 分子产品列表
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- EK1M10
- ELISA试剂盒
Human MMP-10 ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
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- EK1M10S
- ELISA标准品
Human MMP-10 Standard (人基质金属蛋白酶10 标准品)
- ¥280.00