LYVE1 靶点信息

LYVE1 分子靶点信息概述

  • 分子名：LYVE1, lymphatic vessel endothelial hyaluronan receptor 1
  • 别名：LYVE-1
  • 曾用名：XLKD1
  • 全称：extracellular link domain containing 1

LYVE1 分子靶点综述

淋巴管内皮透明质酸受体-1（LYVE-1）作为淋巴管内皮特异性标志物，特异性地表达于淋巴内皮细胞，均匀分布于淋巴管内皮细胞的基底面和胞腔面，其广泛地应用促进肿瘤淋巴转移领域的研究。近年来，LYVE-1本身的生物学功能及其在肿瘤转移领域中发挥的作用已成为肿瘤转移的研究热点之一。阐明LYVE-1在肿瘤淋巴转移中的作用机制，对于建立肿瘤治疗新方法有着重大的意义。

LYVE1, lymphatic vessel endothelial hyaluronan receptor 1 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human LYVE1 分子靶点信息

  • 分子名：LYVE1, lymphatic vessel endothelial hyaluronan receptor 1
  • 别称：
    • cell surface retention sequence binding protein-1
    • cell surface retention sequence-binding protein 1
    • CRSBP-1
    • extracellular link domain containing 1
    • extracellular link domain-containing 1
    • extracellular link domain-containing protein 1
    • HAR
    • hyaluronic acid receptor
    • lymphatic vessel endothelial hyaluronic acid receptor 1
    • LYVE-1
    • XLKD1
  • 基因序列：NCBI_Gene: 10894
  • 蛋白序列：UniProtKB: Q9Y5Y7

人 Human LYVE1靶点分子功能（预测）

Predicted to enable hyaluronic acid binding activity and transmembrane signaling receptor activity. Predicted to be involved in anatomical structure morphogenesis; cell-matrix adhesion; and response to wounding. Predicted to act upstream of or within glycosaminoglycan catabolic process. Located in extracellular exosome.

小鼠 Mouse Lyve1 分子靶点信息

  • 分子名：Lyve1, lymphatic vessel endothelial hyaluronan receptor 1
  • 别称：
    • 1200012G08Rik
    • extra cellular link domain-containing 1
    • lymphatic vessel endothelial HA receptor-1
    • Lyve-1
    • RIKEN cDNA 1200012G08 gene
    • Xlkd1
  • 基因序列：NCBI_Gene: 114332
  • 蛋白序列：

小鼠 Mouse Lyve1 靶点分子功能（预测）

Enables hyaluronic acid binding activity and transmembrane signaling receptor activity. Acts upstream of or within glycosaminoglycan catabolic process. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hemolymphoid system; meninges; and metanephros. Orthologous to human LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1).

大鼠 Rat Lyve1 分子靶点信息

  • 分子名：Lyve1, lymphatic vessel endothelial hyaluronan receptor 1
  • 别称：
    • extra cellular link domain-containing 1
    • extracellular link domain-containing 1
    • LOC293186
    • lymphatic vessel endothelial hyaluronic acid receptor 1
    • Xlkd1
  • 基因序列：NCBI_Gene: 293186
  • 蛋白序列：UniProtKB: D3ZD19

大鼠 Rat Lyve1 靶点分子功能（预测）

Predicted to enable hyaluronic acid binding activity and transmembrane signaling receptor activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within glycosaminoglycan catabolic process. Predicted to be located in cell periphery. Predicted to be active in plasma membrane. Orthologous to human LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1).

LYVE1 分子产品列表

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