IL7 靶点信息

IL7 分子靶点信息概述

  • 分子名：IL7, interleukin 7
  • 基因家族：Interleukins
  • 别名：IL-7

IL7 分子靶点综述

白细胞介素7(IL-7)是一种由骨髓和胸腺基质细胞分泌产生的造血生长因子，它也可由角质形成细胞、树突状细胞、肝细胞、神经元和上皮细胞产生，但是正常的淋巴细胞不能产生IL-7。IL-7刺激多能造血干细胞向淋巴系祖细胞的分化，同样也可刺激所有淋巴系细胞(B细胞、T细胞和NK细胞)的增殖。IL-7促进恶性血液病(急性淋巴细胞白血病、T细胞淋巴瘤)的发展，升高的IL-7水平在HIV感染患者血浆中被检测到，IL-7也可提高异体干细胞移植后的免疫康复。

IL7, interleukin 7 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human IL7 分子靶点信息

人 Human IL7靶点分子功能（预测）

Enables cytokine activity. Involved in cytokine-mediated signaling pathway; positive regulation of chemokine production; and positive regulation of cytokine-mediated signaling pathway. Located in extracellular region. Part of collagen-containing extracellular matrix. Implicated in epidermodysplasia verruciformis. Biomarker of Alzheimer's disease and COVID-19.

小鼠 Mouse Il7 分子靶点信息

小鼠 Mouse Il7 靶点分子功能（预测）

Enables cytokine activity and growth factor activity. Acts upstream of or within several processes, including negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; positive regulation of lymphocyte activation; and tissue homeostasis. Located in extracellular space. Is expressed in several structures, including brain; branchial arch; hemolymphoid system; intestine; and lymphatic system. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human IL7 (interleukin 7).

大鼠 Rat Il7 分子靶点信息

大鼠 Rat Il7 靶点分子功能（预测）

Predicted to enable cytokine activity and growth factor activity. Involved in cellular response to hypoxia and response to X-ray. Predicted to be located in extracellular space. Used to study high grade glioma. Biomarker of periodontal disease. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human IL7 (interleukin 7).

IL7 分子产品列表

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