IL20 靶点信息

IL20 分子靶点信息概述

  • 分子名：IL20, interleukin 20
  • 基因家族：Interleukins
  • 别名：ZCYTO10; IL10D; IL-20

IL20 分子靶点综述

白细胞介素 2 (IL-2)是 15 kDa 的糖蛋白，在人类中，由位于 4 号染色体 q26 – 28 区域的单基因编码。它是免疫系统中的一类信号分子，调控对具有免疫功能的白血球 (白细胞，通常是淋巴 细胞)的活性。IL-2 是机体对微生物感染的天然应答，区别外来和自身抗原。IL-2 通过与 IL-2 受体 来发挥功能，其受体由 3 条链组成，分别为α链 (CD25)、β链 (CD122)和γ链 (CD132)。监测血清中的 IL-2 含量为多种病理状态提供更详细的视角，包括癌症、传染病、移植排斥、 多发性硬化症、类风湿性关节炎、系统性红斑狼疮和 I 型糖尿病等。

IL20, interleukin 20 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human IL20 分子靶点信息

  • 分子名：IL20, interleukin 20
  • 别称：
    • cytokine Zcyto10
    • four alpha helix cytokine
    • IL-20
    • IL10D
    • interleukin-20
    • MGC96907
    • ZCYTO10
  • 基因序列：NCBI_Gene: 50604
  • 蛋白序列：UniProtKB: Q9NYY1

人 Human IL20靶点分子功能（预测）

Predicted to enable interleukin-20 receptor binding activity. Predicted to be involved in positive regulation of keratinocyte differentiation; positive regulation of tyrosine phosphorylation of STAT protein; and regulation of inflammatory response. Predicted to act upstream of or within positive regulation of osteoclast differentiation. Predicted to be located in extracellular region. Implicated in psoriasis. Biomarker of end stage renal disease and rheumatoid arthritis.

小鼠 Mouse Il20 分子靶点信息

小鼠 Mouse Il20 靶点分子功能（预测）

Enables cytokine activity; interleukin-20 receptor binding activity; and interleukin-22 receptor binding activity. Acts upstream of or within positive regulation of osteoclast differentiation. Located in extracellular space. Is expressed in Harderian gland; ductus deferens; epididymis; prostate gland; and skin. Human ortholog(s) of this gene implicated in psoriasis. Orthologous to human IL20 (interleukin 20).

大鼠 Rat Il20 分子靶点信息

  • 分子名：Il20, interleukin 20
  • 别称：
    • If2d
    • interferon 2d
    • interleukin-20
    • LOC681112
    • similar to interleukin 20
  • 基因序列：NCBI_Gene: 681112
  • 蛋白序列：UniProtKB: D4A2T8

大鼠 Rat Il20 靶点分子功能（预测）

Predicted to enable cytokine activity; interleukin-20 receptor binding activity; and interleukin-22 receptor binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within positive regulation of osteoclast differentiation. Predicted to be located in extracellular space. Biomarker of end stage renal disease. Human ortholog(s) of this gene implicated in psoriasis. Orthologous to human IL20 (interleukin 20).

IL20 分子产品列表

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