CXCR5/CD185 靶点信息

CXCR5/CD185 分子靶点信息概述

  • 分子名：CXCR5, C-X-C motif chemokine receptor 5
  • 别名：MDR15; CD185
  • 曾用名：BLR1
  • 全称：Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); chemokine (C-X-C motif) receptor 5

CXCR5/CD185 靶点信息

CXCR5（C-X-趋化因子受体5型，CD185）也称为Burkitt淋巴瘤受体1（BLR1）属于CXC趋化因子家族。CXCR5是趋化因子BLC的七次跨膜G蛋白偶联受体。CXCR5基因在Burkitt淋巴瘤和淋巴组织中特异性表达，如淋巴结中的滤泡以及脾脏中。对CXCR5的研究表明，它在B细胞迁移中起着重要作用。CXCR5在人类血液和唾液腺以及动物淋巴器官、血液、骨髓、大脑、肝脏、淋巴结、皮肤、脾脏、胃和扁桃体中均有表达。

CXCR5, C-X-C motif chemokine receptor 5 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human CXCR5/CD185 分子靶点信息

  • 分子名：CXCR5, C-X-C motif chemokine receptor 5
  • 别称：
    • BLR1
    • Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)
    • Burkitt lymphoma receptor 1, GTP-binding protein
    • C-X-C chemokine receptor type 5
    • CD185
    • chemokine (C-X-C motif) receptor 5
    • CXC-R5
    • CXCR-5
    • MDR-15
    • MDR15
    • MGC117347
    • monocyte-derived receptor 15
  • 基因序列：NCBI_Gene: 643
  • 蛋白序列：UniProtKB: P32302

人 Human CXCR5/CD185 靶点分子功能（预测）

Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Involved in positive regulation of cytokinesis. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane.

小鼠 Mouse Cxcr5 分子靶点信息

小鼠 Mouse Cxcr5 靶点分子功能（预测）

Predicted to enable C-X-C chemokine receptor activity. Acts upstream of or within leukocyte chemotaxis and lymph node development. Located in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR5 (C-X-C motif chemokine receptor 5).

大鼠 Rat Cxcr5 分子靶点信息

  • 分子名：Cxcr5, C-X-C motif chemokine receptor 5
  • 别称：
    • Blr1
    • Burkitt lymphoma receptor 1
    • burkitt lymphoma receptor 1 homolog
    • C-X-C chemokine receptor type 5
    • chemochine (C-X-C motif) receptor 5
    • chemokine (C-X-C motif) receptor 5
    • CXC-R5
    • CXCR-5
    • neurolymphatic receptor
    • NLR
  • 基因序列：NCBI_Gene: 29363
  • 蛋白序列：

大鼠 Rat Cxcr5 靶点分子功能（预测）

Predicted to enable C-X-C chemokine receptor activity. Predicted to be involved in immune response and positive regulation of cytokinesis. Predicted to act upstream of or within leukocyte chemotaxis and lymph node development. Predicted to be located in external side of plasma membrane. Orthologous to human CXCR5 (C-X-C motif chemokine receptor 5).

CXCR5/CD185 分子产品列表

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