人 Human CXCL8 分子靶点信息

• 分子名：CXCL8, C-X-C motif chemokine ligand 8
• 别称：
  • alveolar macrophage chemotactic factor I
  • beta endothelial cell-derived neutrophil activating peptide
  • beta-thromboglobulin-like protein
  • C-X-C motif chemokine 8
  • chemokine (C-X-C motif) ligand 8
  • emoctakin
  • GCP-1
  • GCP1
  • granulocyte chemotactic protein 1
  • IL8
  • interleukin 8
  • interleukin-8
  • LECT
  • LUCT
  • lung giant cell carcinoma-derived chemotactic protein
  • lymphocyte derived neutrophil activating peptide
  • lymphocyte-derived neutrophil-activating factor
  • LYNAP
  • MDNCF
  • MONAP
  • monocyte-derived neutrophil chemotactic factor
  • monocyte-derived neutrophil-activating peptide
  • NAF
  • NAP-1
  • NAP1
  • neutrophil-activating peptide 1
  • SCYB8
  • small inducible cytokine subfamily B, member 8
  • T cell chemotactic factor
  • T-cell chemotactic factor
  • tumor necrosis factor-induced gene 1
• 基因序列：NCBI_Gene: 3576
• 蛋白序列：UniProtKB: P10145

人 Human CXCL8靶点分子功能（预测）

Enables chemokine activity and interleukin-8 receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; induction of positive chemotaxis; and neutrophil chemotaxis. Acts upstream of or within negative regulation of cell adhesion molecule production; positive regulation of cellular biosynthetic process; and regulation of gene expression. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in several diseases, including autoimmune uveitis; bacterial gastritis; gastrointestinal system cancer (multiple); trachoma; and urinary tract infection. Biomarker of several diseases, including chikungunya; cholestasis (multiple); cystic fibrosis; liver disease (multiple); and tuberculosis (multiple).