文章目录[隐藏]
CD69 分子靶点信息概述
- 分子名:CD69, CD69 molecule
- 基因家族:CD molecules; C-type lectin domain containing
- 别名:CLEC2C
- 全称:CD69 antigen (p60, early T-cell activation antigen)
CD69 分子靶点综述
CD69 是一种 II 型跨膜糖蛋白,属于 C-型凝集素受体家族,也是 NK 细胞信号转导基因复合体家族的一员。它是 T 淋巴细胞激活后最早表达的表面抗原,当其表达后,可作为共刺激信号促进 T 细胞进一步活化和增殖。CD69 也在 NK 细胞、B 细胞、巨噬细胞、中性和嗜酸性粒细胞上诱导表达。表达 CD69 的活化 T细胞主要是 CD8+CD45RO+,而且主要受 IL-15 诱导以及与表达 ICAM-1 的活化内皮接触有关。当外源性刺激消失后,活化 T 细胞的 CD69 表达即可快速降低。因此,淋巴细胞暴露于某种抗原刺激后表达 CD69的程度可反映细胞对于该抗原的反应程度。
CD69, CD69 molecule 分子靶点种属信息
人 Human CD69 分子靶点信息
- 分子名:CD69, CD69 molecule
- 别称:
- activation inducer molecule (AIM/CD69)
- AIM
- BL-AC/P26
- C-type lectin domain family 2 member C
- C-type lectin domain family 2, member C
- CD69 antigen (p60, early T-cell activation antigen)
- CLEC2C
- EA1
- early activation antigen CD69
- early lymphocyte activation antigen
- early T-cell activation antigen p60
- GP32/28
- leukocyte surface antigen Leu-23
- MLR-3
- 基因序列:NCBI_Gene: 969
- 蛋白序列:UniProtKB: Q07108
人 Human CD69靶点分子功能(预测)
Enables identical protein binding activity. Predicted to act upstream of or within cellular response to xenobiotic stimulus. Part of protein-containing complex.
小鼠 Mouse Cd69 分子靶点信息
- 分子名:Cd69, CD69 antigen
- 别称:
- 5830438K24Rik
- AI452015
- AIM
- EST AI452015
- RIKEN cDNA 5830438K24 gene
- VEA
- 基因序列:NCBI_Gene: 12515
- 蛋白序列:
小鼠 Mouse Cd69 靶点分子功能(预测)
Predicted to enable calcium ion binding activity and identical protein binding activity. Located in external side of plasma membrane. Orthologous to human CD69 (CD69 molecule).
大鼠 Rat Cd69 分子靶点信息
- 分子名:Cd69, Cd69 molecule
- 别称:
- C-type lectin domain family 2 member A
- CD69 antigen
- early activation antigen CD69
- 基因序列:NCBI_Gene: 29187
- 蛋白序列:UniProtKB: Q5M851
大鼠 Rat Cd69 靶点分子功能(预测)
Enables calcium ion binding activity. Predicted to be involved in complement activation, lectin pathway. Predicted to act upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in cell surface. Predicted to be part of protein-containing complex. Predicted to be active in external side of plasma membrane. Orthologous to human CD69 (CD69 molecule).
CD69 分子产品列表
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- F1106902
- 流式抗体(新品)
Anti-Human CD69, PE (Clone FN50) (新品)
- ¥544.00 – ¥1,192.00
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- F2106902
- 流式抗体(新品)
Anti-Mouse CD69, PE (Clone:H1.2F3)流式抗体 (新品)
- ¥720.00 – ¥1,584.00