CD34靶点信息

CD34 分子靶点信息概述

  • 分子名：CD34, CD34 molecule
  • 基因家族：CD molecules
  • 别名：CD34 antigen
  • 全称：Hematopoietic progenitor cell antigen CD34, CD34 sialomucin

CD34 分子靶点综述

CD34一般是指CD34分子，是一种高度糖基化I型跨膜蛋白，属于钙黏蛋白，是血管内皮细胞、造血干细胞等细胞的标志物。CD34分子，可选择性地表达于早期造血干细胞，以及造血祖细胞、小血管内皮细胞和胚胎成纤维细胞等表面。

CD34, CD34 molecule 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human CD34 分子靶点信息

  • 分子名：CD34, CD34 molecule
  • 别称：
    • CD34 antigen
    • hematopoietic progenitor cell antigen CD34
  • 基因序列：NCBI_Gene: 947
  • 蛋白序列：UniProtKB: P28906

人 Human CD34靶点分子功能（预测）

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and carbohydrate binding activity. Involved in several processes, including blood vessel development; regulation of cellular response to stress; and regulation of cytokine production. Located in external side of plasma membrane; intercellular bridge; and perinuclear region of cytoplasm. Biomarker of thyroid gland carcinoma.

小鼠 Mouse Cd34 分子靶点信息

小鼠 Mouse Cd34 靶点分子功能（预测）

Enables sulfate binding activity. Acts upstream of or within leukocyte migration. Located in cytoplasm; external side of plasma membrane; and extracellular region. Is expressed in several structures, including alimentary system; cardiovascular system; extraembryonic component; genitourinary system; and skin. Orthologous to human CD34 (CD34 molecule).

大鼠 Rat Cd34 分子靶点信息

大鼠 Rat Cd34 靶点分子功能（预测）

Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; carbohydrate binding activity; and sulfate binding activity. Involved in glomerular filtration and mesangial cell-matrix adhesion. Located in apical plasma membrane; basal plasma membrane; and lysosome. Part of glomerular endothelium fenestra. Biomarker of diabetic retinopathy. Orthologous to human CD34 (CD34 molecule).

CD34 分子产品列表

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