Rat IFN-γ Standard (大鼠γ干扰素 标准品)

IFNG 分子靶点信息概述

• 分子名：IFNG, interferon gamma
• 基因家族：Interferons

IFNG 分子靶点综述

IFN-γ主要由Th1型细胞产生，属于II型细胞因子中干扰素家族中的一员，是一类分泌型糖蛋白，由143个氨基酸组成，相对分子质量是16942。IFN-γ主要由活化的T细胞和NK细胞产生，具有调节机体免疫状态，介导细胞免疫，加强受体介导的吞噬功能，增强巨噬细胞和中性粒细胞的杀伤活性，具有抗病毒感染及抗肿瘤等生物学活性。

大鼠 Rat Ifng 分子靶点信息

• 分子名：Ifng, interferon gamma
• 别称：
  • If2f
  • IFN-gamma
  • IFNG2
  • interferon 2f
• 基因序列：NCBI_Gene: 25712
• 蛋白序列：
  • UniprotKB: A0A7R8C3J6
  • UniprotKB: P01581

大鼠 Rat Ifng 靶点分子功能（预测）

Predicted to enable cytokine activity. Involved in several processes, including negative regulation of cell population proliferation; positive regulation of NMDA glutamate receptor activity; and positive regulation of macromolecule metabolic process. Located in several cellular components, including extracellular space; neuron projection; and perikaryon. Used to study several diseases, including Chagas disease; allergic conjunctivitis; allergic rhinitis; renal fibrosis; and ureteral obstruction. Biomarker of several diseases, including abdominal aortic aneurysm; autoimmune thyroiditis; pulpitis; tongue squamous cell carcinoma; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including ataxia telangiectasia; autoimmune disease (multiple); eczema herpeticum; factor VIII deficiency; and leukemia (multiple). Orthologous to human IFNG (interferon gamma).