Rat Adiponectin/Acrp30 Standard (大鼠脂联素 (Adiponectin/Acrp30) 标准品)

ADIPOQ 分子靶点信息概述

• 分子名：ADIPOQ, adiponectin, C1Q and collagen domain containing
• 基因家族：C1q and TNF related
• 别名：ACRP30; apM1; GBP28; adiponectin
• 曾用名：ACDC
• 全称：adipose most abundant gene transcript 1; adiponectin precursor; adipocyte, C1Q and collagen domain containing

ADIPOQ 分子靶点综述

脂联素，又称脂肪细胞补体相关蛋白30(Acrp30)，参与调节葡萄糖水平和脂肪酸分解。它组装成不同的复合物包括三聚体、六聚体和高阶寡聚体结构，进而可能影响生物活性。脂联素是一种蛋白质激素，调节许多代谢过程，包括葡萄糖调节和脂肪酸氧化。脂肪组织(以及妊娠期的胎盘)专门分泌脂联素到血液中，因此相对于其它许多激素，血浆中的脂联素含量很丰富。脂联素可能具有抗动脉粥样硬化和消炎的作用，可负向调节粒单祖细胞的生长和TNF-α在巨噬细胞中的产生。监测一些病理状态下的血清脂联素水平，如2型糖尿病、肥胖、动脉粥样硬化和非酒精性脂肪肝疾病，可为我们了解脂联素提供更详细的见解。

大鼠 Rat Adipoq 分子靶点信息

• 分子名：Adipoq, adiponectin, C1Q and collagen domain containing
• 别称：
  • Acdc
  • Acrp30
  • Adid
  • adipocyte complement related protein of 30 kDa
  • adiponectin
  • adiponectin d
• 基因序列：NCBI_Gene: 246253
• 蛋白序列：
  • UniprotKB: A0A0G2K845
  • UniprotKB: Q8K3R4

大鼠 Rat Adipoq 靶点分子功能（预测）

Enables identical protein binding activity. Involved in several processes, including cellular response to organonitrogen compound; positive regulation of glycogen (starch) synthase activity; and positive regulation of protein phosphorylation. Located in extracellular space. Part of protein-containing complex. Used to study brain infarction. Biomarker of several diseases, including end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); hyperthyroidism; and obesity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing).