PMA/Ionomycin Mixture(250X)佛波酯/离子霉素混合物

引用文献

1. Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 

2. Effects of Gui Zhi Ma Huang Ge Ban Tang on the TLR7 Pathway in Influenza Virus Infected Mouse Lungs in a Cold Environment 

3. Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway 

4. Qing-Luo-Yin Alleviated Experimental Arthritis in Rats by Disrupting Immune Feedback Between Inflammatory T Cells and Monocytes: Key Evidences from Its Effects on Immune Cell Phenotypes 

5. LncRNA AK085865 depletion ameliorates asthmatic airway inflammation by modulating macrophage polarization 

6. Against NF-κB/thymic stromal lymphopoietin signaling pathway, catechin alleviates the inflammation in allergic rhinitis 

7. Sodium Butyrate Ameliorates Streptozotocin-Induced Type 1 Diabetes in Mice by Inhibiting the HMGB1 Expression 

8. Enhanced immunogenicity of the tuberculosis subunit Rv0572c vaccine delivered in DMT liposome adjuvant as a BCG-booster 

9. Engrafted peripheral blood-derived mesenchymal stem cells promote locomotive recovery in adult rats after spinal cord injury 

10. Tissue-resident CD69+CXCR6+ Natural Killer cells with exhausted phenotype accumulate in human non-small cell lung cancer 

11. A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide–Autoreactive CD4+ and CD8+ T Cells 

12. Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation 

13. Rhubarb Peony Decoction ameliorates ulcerative colitis in mice by regulating gut microbiota to restoring Th17/Treg balance 

14. Clinical evaluation of vitamin D status and its relationship with disease activity and changes of intestinal immune function in patients with Crohn’s disease in the Chinese population 

15. Qing-Chang-Hua-Shi granule ameliorates DSS-induced colitis by activating NLRP6 signaling and regulating Th17/Treg balance 

16. The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis 

17. Next generation sequencing for miRNA profile of spleen CD4+ T cells in the murine model of acute asthma 

18. Interaction between Kynurenine and Aryl Hydrocarbon Receptor in Regulating the Balance of T helper 17 Cells and Regulatory T-cells in Decidua during Early Gestation 

19. An intronic polymorphism of NFATC1 gene shows a risk association with biopsy-proven acute rejection in renal transplant recipients 

20. Morin, the PPARγ agonist, inhibits Th17 differentiation by limiting fatty acid synthesis in collagen-induced arthritis 

21. Conjugation Reaction with 8-Arm PEG Markedly Improves the Immunogenicity of Mycobacterium tuberculosis CFP10-TB10.4 Fusion Protein 

22. In-situ administration of dendritic cells following argon–helium cryosurgery enhances specific antiglioma immunity in mice 

23. Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells 

24. ICS/LABA Combined With Subcutaneous Immunotherapy Modulates the Th17/Treg Imbalance in Asthmatic Children 

25. Tanshinone IIA ameliorates myocardial ischemia/reperfusion injury in rats by regulation of NLRP3 inflammasome activation and Th17 cells differentiation 

26. Cholinergic neuron-like D-U87 cells promote polarization of allergic rhinitis T-helper 2 cells 

27. Inconsistence between number and function of autoreactive T cells in the course of experimental autoimmune encephalomyelitis 

28. Elevated Th17 cell frequencies and Th17/Treg ratio are associated with airway hyperresponsiveness in asthmatic children 

29. Isoflurane attenuates murine lupus nephritis by inhibiting NLRP3 inflammasome activation 

30. Caveolin-1 Promotes the Imbalance of Th17/Treg in Patients with Chronic Obstructive Pulmonary Disease 

31. Cow, Goat, and Mare Milk Diets Differentially Modulated the Immune System and Gut Microbiota of Mice Colonized by Healthy Infant Feces 

32. Association between the ratio of aryl hydrocarbon receptor (AhR) in Th17 cells to AhR in Treg cells and SLE skin lesions 

33. Sinomenine induces the generation of intestinal Treg cells and attenuates arthritis via activation of aryl hydrocarbon receptor 

34. Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues 

35. Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic Fibrosis via Modulating TGFβ1 and Akt Signaling and Shifting Th1/Th2 Balance in Schistosoma japonicum-Infected Mice 

36. Quercetin attenuates collagen-induced arthritis by restoration of Th17/Treg balance and activation of Heme Oxygenase 1-mediated anti-inflammatory effect 

37. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues 

38. Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons 

39. The immunosuppressant fingolimod ameliorates experimental autoimmune myasthenia gravis by regulating T-cell balance and cytokine secretion 

40. Human milk and infant formula modulate the intestinal microbiota and immune systems of human microbiota-associated mice 

41. Jieduquyuziyin prescription suppresses IL-17 production and Th17 activity in MRL/lpr mice by inhibiting expression of Ca2+/calmodulin-dependent protein kinase-4 

42. Schistosoma japonicum peptide SJMHE1 suppresses airway inflammation of allergic asthma in mice 

43. Clinical significance of CD8+ T cell immunoreceptor with Ig and ITIM domains+ in locally advanced gastric cancer treated with SOX regimen after D2 gastrectomy 

44. Fructooligosaccharides protect against OVA-induced food allergy in mice by regulating the Th17/Treg cell balance using tryptophan metabolites 

45. MicroRNA124-IL6R Mediates the Effect of Nicotine in Inflammatory Bowel Disease by Shifting Th1/Th2 Balance Toward Th1 

46. Elevated granulocytic myeloid-derived suppressor cells are closely related with elevation of Th17 cells in mice with experimental asthma 

47. Hyperoside Suppresses Renal Inflammation by Regulating Macrophage Polarization in Mice With Type 2 Diabetes Mellitus 

48. SJMHE1 Peptide from Schistosoma japonicum Inhibits Asthma in Mice by Regulating Th17/Treg Cell Balance via miR-155 

49. Elevation of Circulating Th17/Th22 Cells Exposed to Low-Level Formaldehyde and Its Relevance to Formaldehyde-Induced Occupational Allergic Contact Dermatitis 

50. P2X7 Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway 

51. Dll4 in the DCs isolated from OVA-sensitized mice is involved in Th17 differentiation inhibition by 1,25-dihydroxyvitamin D3 in vitro 

52. hPMSCs inhibit the expression of PD-1 in CD4+IL-10+ T cells and mitigate liver damage in a GVHD mouse model by regulating the crosstalk between Nrf2 and NF-κB signaling pathway 

53. The Role of IL-23/Th17 Pathway in Patients with Primary Immune Thrombocytopenia 

54. Cyclin G2 in macrophages triggers CTL-mediated antitumor immunity and antiangiogenesis via interferon-gamma 

55. Response Gene to Complement-32 Promotes the Imbalance of Treg/Th17 in Patients with Dilated Cardiomyopathy 

56. Next Generation Sequencing for Long Non-coding RNAs Profile for CD4+ T Cells in the Mouse Model of Acute Asthma 

57. The role of GLS1-mediated glutaminolysis/2-HG/H3K4me3 and GSH/ROS signals in Th17 responses counteracted by PPARγ agonists 

58. Single-cell transcriptomics of peripheral blood reveals anti-tumor systemic immunity induced by oncolytic virotherapy 

59. Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease 

60. Natural killer T cell/IL-4 signaling promotes bone marrow-derived fibroblast activation and M2 macrophage-to-myofibroblast transition in renal fibrosis 

61. Paeoniflorin ameliorates murine lupus nephritis by increasing CD4+Foxp3+ Treg cells via enhancing mTNFα-TNFR2 pathway 

62. Different Expression Characteristics of LAG3 and PD-1 in Sepsis and Their Synergistic Effect on T Cell Exhaustion: A New Strategy for Immune Checkpoint Blockade 

63. Ag85b/ESAT6-CFP10 adjuvanted with aluminum/poly-IC effectively protects guinea pigs from latent mycobacterium tuberculosis infection 

64. Voluven treatment could induce NLRP3 inflammasome-mediated pyroptosis of bone marrow-derived macrophages 

65. Once-monthly hemin suppresses inflammatory and autoreactive CD4+ T cell responses to robustly ameliorate experimental rheumatoid arthritis 

66. The co-expression characteristics of LAG3 and PD-1 on the T cells of patients with breast cancer reveal a new therapeutic strategy 

67. GeGen QinLian decoction alleviate influenza virus infectious pneumonia through intestinal flora 

68. The expression and function of immunoglobulin-like transcript 4 in dendritic cells from patients with hepatocellular carcinoma 

69. Carrier-free subunit nanovaccine amplifies immune responses against tumors and viral infections 

70. Pseudomonas aeruginosa quorum-sensing metabolite induces host immune cell death through cell surface lipid domain dissolution 

71. Effect of peripheral blood-derived mesenchymal stem cells on macrophage polarization and Th17/Treg balance in vitro 

72. Compound 511 ameliorates MRSA-induced lung injury by attenuating morphine-induced immunosuppression in mice via PI3K/AKT/mTOR pathway 

73. Immunologic Response to Tumor Ablation with Irreversible Electroporation 

74. TIGIT marks exhausted T cells and serves as a target for immune restoration in patients with chronic HBV infection 

75. Hyperglycemia Enhances Immunosuppression and Aerobic Glycolysis of Pancreatic Cancer Through Upregulating Bmi1-UPF1-HK2 Pathway 

76. Schistosoma japonicum peptide SJMHE1 inhibits acute and chronic colitis induced by dextran sulfate sodium in mice 

77. Gut Microflora Modulates Th17/Treg Cell Differentiation in Experimental Autoimmune Prostatitis via the Short-Chain Fatty Acid Propionate 

78. PTPN21-CDSlong isoform inhibits the response of acute lymphoblastic leukemia cells to NK-mediated lysis via the KIR/HLA-I axis 

79. Diallyl Trisulfide can induce fibroblast-like synovial apoptosis and has a therapeutic effect on collagen-induced arthritis in mice via blocking NF-κB and Wnt pathways 

80. STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer 

81. Metabolic Reprogramming of CD4+ T Cells by Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuates Autoimmune Hepatitis Through Mitochondrial Protein Transfer 

82. Hepatocyte-specific Smad4 deficiency inhibits hepatocarcinogenesis by promoting CXCL10/CXCR3-dependent CD8+- T cell-mediated anti-tumor immunity 

83. Therapeutic potential of tLyp-1-EV-shCTCF in inhibiting liver cancer stem cell self-renewal and immune escape via SALL3 modulation in hepatocellular carcinoma 

84. Mesothelin CAR-engineered NK cells derived from human embryonic stem cells suppress the progression of human ovarian cancer in animals 

85. The potential role of lung microbiota and lauroylcarnitine in T-cell activation associated with checkpoint inhibitor pneumonitis 

86. C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial 

87. Lactobacillus plantarum P9 ameliorates dysfunctional immune and metabolic homeostasis along the gut–liver axis in a nonalcoholic fatty liver disease with low-grade colitis mouse model 

88. KLRG1-expressing CD8+ T cells are exhausted and polyfunctional in patients with chronic hepatitis B 

89. Trefoil factor 3 can stimulate Th17 cell response in the development of type 2 diabetes mellitus 

90. The expression of CTLA-4 in hepatic alveolar echinococcosis patients and blocking CTLA-4 to reverse T cell exhaustion in Echinococcus multilocularis-infected mice 

91. Baricitinib relieves DSS-induced ulcerative colitis in mice by suppressing the NF-κB and JAK2/STAT3 signalling pathways 

92. ERK/MEK Pathway Regulates Th17 Cell Differentiation in Patients with Pemphigus Vulgaris 

93. Unbalanced Aryl Hydrocarbon Receptor Expression in Peripheral and Lesional T Cell Subsets of Atopic Dermatitis 

94. Higher PD-1/Tim-3 expression on IFN-γ+ T cells is associated with poor prognosis in patients with acute myeloid leukemia 

95. Loss of ADAR1 in macrophages in combination with interferon gamma suppresses tumor growth by remodeling the tumor microenvironment 

96. DCTPP1, a Reliable Q-Biomarker for Comprehensive Evaluation of the Quality of Tripterygium Glycoside Tablets Based on Chemical References 

97. High glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment 

98. The changes of expressive levels of IL-17A, STAT3 and RORγt in different invasive pulmonary aspergillosis mice 

99. Schistosoma japonicum-derived peptide SJMHE1 ameliorates allergic symptoms and responses in mice with allergic rhinitis 

100. Intestinal Toxicity of Metal Nanoparticles: Silver Nanoparticles Disorder the Intestinal Immune Microenvironment 

101. Gut microbiota induces hepatic steatosis by modulating the T cells balance in high fructose diet mice 

102. Nanovaccines Fostering Tertiary Lymphoid Structure to Attack Mimicry Nasopharyngeal Carcinoma 

103. Immunomodulatory effects of umbilical mesenchymal stem cell-derived exosomes on CD4+ T cells in patients with primary Sj?gren's syndrome 

104. Xin-Li formula attenuates heart failure induced by a combination of hyperlipidemia and myocardial infarction in rats via Treg immunomodulation and NLRP3 inflammasome inhibition 

105. PEGylated and CD47-conjugated nanoellipsoidal artificial antigen-presenting cells minimize phagocytosis and augment anti-tumor T-cell responses 

106. Tacrolimus improved the pregnancy outcomes of patients with refractory recurrent spontaneous abortion and immune bias disorders: a randomized controlled trial 

107. Mucosa-associated lymphoid tissue lymphoma translocation protein 1 exaggerates multiple organ injury, inflammation, and immune cell imbalance by activating the NF-κB pathway in sepsis 

108. Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a Boosting Vaccine for BCG 

109. Increased IFN-γ+ and TNF-α+ mucosal-associated invariant T cells in patients with aplastic anemia 

110. Tumor cell vaccine combined with Newcastle disease virus promote immunotherapy of lung cancer 

111. Effects of lactate on metabolism and differentiation of CD4+T cells 

112. 皮肤 皮肤损伤组织 组织匀浆 血清

     Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation 

113. 细胞培养上清 血清

     Casein Kinase II exacerbates rheumatoid arthritis via promoting Th1 and Th17 cell inflammatory responses 

114. Peripheral Th17/Treg Cell-Mediated Immunity Imbalance in Allergic Rhinitis Patients 

115. Mbd2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting Irf4 Expression 

116. Immunologic Response to Tumor Ablation with Irreversible Electroporation 

117. In-Situ Administration of Dendritic Cells Following Argon-Helium Cryosurgery Enhances Specific Antiglioma Immunity in Mice 

118. Next Generation Sequencing for Mirna Profile of Spleen Cd4(+) T Cells in the Murine Model of Acute Asthma 

119. Norisoboldine Ameliorates Dss-Induced Ulcerative Colitis in Mice through Induction of Regulatory T Cells in Colons 

120. Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model 

1
Qin Z, Wang P-Y, Wan J-J, Zhang Y, Wei J, Sun Y and Liu X (2020) MicroRNA124-IL6R Mediates the Effect of Nicotine in Inflammatory Bowel Disease by Shifting Th1/Th2 Balance Toward Th1. Front. Immunol. 11:235. doi: 10.3389/fimmu.2020.00235

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2
Wan X, Pei W Y, Zhang L, et al. A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide–Autoreactive CD4+ and CD8+ T Cells[J]. The Journal of Immunology, 2019 （IF:4.5)

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3
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4
Liu Y, Chen Z, Xu K, et al. Next generation sequencing for miRNA profile of spleen CD4 +, T cells in the murine model of acute asthma[J]. Epigenomics, 2018 (IF:4.404)

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5
Xiaoxiang Li, Kui Xu, Wei Li, et al. Immunologic Response to Tumor Ablation with Irreversible Electroporation[J]. PLOS ONE, 2012, 7(11): e48749 (IF:4.092)

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6
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7
Yong Yuan, Bo Yang, Zuowu Ye, et al. Sceptridium ternatum extract exerts antiasthmatic effects by regulating Th1/Th2 balance and the expression levels of leukotriene receptors in a mouse asthma model[J]. J ETHNOPHARMACOL, 2013, 149: 701-706 (IF:2.755)

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8
Lin C, Wang Q, Lu G, et al. In-situ administration of dendritic cells following argon-helium cryosurgery enhances specific antiglioma immunity in mice[J]. Neuroreport, 2014, 25: 900-908 (IF:1.343)

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9
Lv Q, Qiao S M, Xia Y, et al. Norisoboldine ameliorates DSS-induced ulcerative colitis in mice through induction of regulatory T cells in colons[J]. International Immunopharmacology, 2015, 29(2) (IF:2.472)

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10
Tong Bei, Yu Juntao, Wang Ting, et al. Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues[J]. Molecular Immunology, 2015, 65: 94-103 (IF:2.973)

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11
Tong Bei, Dou Yannong, Wang Ting, et al. Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues[J]. Toxicology and Applied Pharmacology, 2015, 282: 90-99 (IF:3.705)

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12
Shui B, Xia W, Wen C, et al. Jieduquyuziyin prescription suppresses IL-17 production and Th17 activity in MRL/lpr mice by inhibiting expression of Ca2+/calmodulin-dependent protein kinase-4[J]. Journal of Natural Medicines, 2015, 69(3): 349-357 (IF:1.593)

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13
Ye X, Zhang L, Wang H, et al. The Role of IL-23/Th17 Pathway in Patients with Primary Immune Thrombocytopenia[J]. PLOS ONE, 2015, 10(1): e0117704 (IF:3.234)

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14
Shunlan N, Shanshan L, Naibin Y, et al. Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model[J]. Mediators of Inflammation, 2017, 2017: 1-10 (IF:3.418)

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15
Aijun J, Yueling W, Wenjin S, et al. MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression[J]. Mediators of Inflammation, 2017, 2017: 1-10 (IF:3.232)

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16
Li X, Sun W J, Jia A J, et al. MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α[J]. Journal of Inflammation, 2018, 15(1): 15 (IF:2.208)

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17
Xuekun Huang, Yulian Chen, Fucheng Zhang, et al. Peripheral Th17/Treg cell-mediated immunity imbalance in allergic rhinitis patients[J]. BRAZ J OTORHINOLAR, 2014, 80(2): 152-155 (IF:0.545)

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18
Wan X,et al.A Tolerogenic Artificial APC Durably Ameliorates Experimental Autoimmune Encephalomyelitis by Directly and Selectively Modulating Myelin Peptide–Autoreactive CD4+ and CD8+ T Cells[J].The Journal of Immunology,2019（IF=4.5)

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19
Yu H T, Jiang L L, Liu R Q, et al. Association between the ratio of aryl hydrocarbon receptor (AhR) in Th17 cells to AhR in Treg cells and SLE skin lesions[J]. International Immunopharmacology, 2019, 69: 257-262 (IF:3.361)

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