CS0002
Ionomycin Calcium（离子霉素）
¥460.00 – ¥4,460.00
在售SKU:70-CS0002, 70-CS0002-500
描述
在售SKU:CS0002-500, CS0002
1.产品简介
佛波酯(Phorbol 12-Myristate 13-Acetate, PMA)和离子霉素(ionomycin)处理足以诱导很多类型的细胞活化，分泌细胞因子。该混合物可用于刺激体外培养细胞产生细胞因子，随后用免疫学方法进行检测。还可以与蛋白转运抑制剂联合使用，使诱导的细胞因子滞留在胞内。Ionomycin的推荐工作浓度是1 - 5 μg/ml，但需要研究者对实验条件和效果进行优化和判断。
2.产品特点
•诱导细胞活化能力强
•操作简单
•常备现货
引用文献统计
该产品被引用的文献总数为：66
- PP2Cδ Controls the Differentiation and Function of Dendritic Cells Through Regulating the NSD2/mTORC2/ACLY Pathway
影响因子：8.786刊物：Frontiers in Immunology发表日期：2022/1/7 - Increased Proportion of Dual-Positive Th2–Th17 Cells Promotes a More Severe Subtype of Asthma
影响因子：2.409刊物：Canadian Respiratory Journal发表日期：2021/8/6 - Immune response pattern varies with the natural history of chronic hepatitis B
影响因子：3.411刊物：WORLD JOURNAL OF GASTROENTEROLOGY发表日期：2019/4/28 - Role of TLR5 in the Translocation and Dissemination of Commensal Bacteria in the Intestine after Traumatic Hemorrhagic Shock
影响因子：4.818刊物：Journal of Immunology Research发表日期：2021/11/19 - Clinical correlation of peripheral CD4+‑cell sub‑sets, their imbalance and Parkinson's disease
影响因子：1.554刊物：Molecular Medicine Reports发表日期：2015/7/29 - Single-cell multi-omics analysis presents the landscape of peripheral blood T-cell subsets in human chronic prostatitis/chronic pelvic pain syndrome
影响因子：4.486刊物：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE发表日期：2020/10/30 - Effects of Dezocine and Sufentanil on Th1/Th2 Balance in Breast Cancer Patients Undergoing Surgery
影响因子：4.319刊物：Drug Design Development and Therapy发表日期：2022/9/30 - Impaired granzyme B-producing regulatory B cells in systemic lupus erythematosus
影响因子：4.407刊物：MOLECULAR IMMUNOLOGY发表日期：2021/11/5 - Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation
影响因子：3.795刊物：IMMUNOLOGY发表日期：2015/1/27 - Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
影响因子：9.995刊物：Cell Reports发表日期：2022/10/25 - Expression and significance of peripheral myeloid-derived suppressor cells in chronic hepatitis B patients
影响因子：2.623刊物：Clinics and Research in Hepatology and Gastroenterology发表日期：2018/5/10 - Decreased frequency of circulating Th9 cells in patients with chronic hepatitis B infection
影响因子：1.521刊物：JOURNAL OF CLINICAL LABORATORY ANALYSIS发表日期：2017/5/8 - Increased regulatory T cells and eosinophils characterize atopic dermatitis–like graft-versus-host disease compared with lichen planus–like graft-versus-host disease
影响因子：7.102刊物：JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY发表日期：2019/8/9 - Therapeutic Effect of Xuebijing, a Traditional Chinese Medicine Injection, on Rheumatoid Arthritis
影响因子：1.813刊物：Evidence-based Complementary and Alternative Medicine发表日期：2020/1/28 - MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression.
影响因子：3.232刊物：MEDIATORS OF INFLAMMATION发表日期：2017/7/20 - MBD2-mediated Th17 differentiation in severe asthma is associated with impaired SOCS3 expression
影响因子：3.309刊物：EXPERIMENTAL CELL RESEARCH发表日期：2018/8/9 - MBD2 regulates differentiation and function of Th17 cells in neutrophils- dominant asthma via HIF-1α
影响因子：2.61刊物：Journal of Inflammation-London发表日期：2018/8/20 - CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues
影响因子：3.73刊物：PLoS One发表日期：2013/6/18 - Resveratrol exerts antitumor effects by downregulating CD8+CD122+ Tregs in murine hepatocellular carcinoma
影响因子：5.869刊物：OncoImmunology发表日期：2020/10/24 - Colorectal Cancer Progression Is Associated with Accumulation of Th17 Lymphocytes in Tumor Tissues and Increased Serum Levels of Interleukin-6
影响因子：1.283刊物：TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE发表日期：2014/7/2 - Dysbiosis of gut microbiota induced the disorder of helper T cells in influenza virus-infected mice
影响因子：2.366刊物：Human Vaccines & Immunotherapeutics发表日期：2015/5/27 - NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia
影响因子：3.298刊物：Journal of Immunology Research发表日期：2018/7/22 - Probiotics alleviate adipose inflammation in high-fat diet–induced obesity by restoring adipose invariant natural killer T cells
影响因子：4.008刊物：NUTRITION发表日期：2021/4/25 - Polysaccharide from Radix Codonopsis has beneficial effects on the maintenance of T-cell balance in mice
影响因子：3.743刊物：BIOMEDICINE & PHARMACOTHERAPY发表日期：2019/2/20 - Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines
影响因子：1.692刊物：Molecular Medicine Reports发表日期：2017/9/25 - Exposure to biomass smoke induces pulmonary Th17 cell differentiation by activating TLR2 on dendritic cells in a COPD rat model
影响因子：4.374刊物：TOXICOLOGY LETTERS发表日期：2021/5/28 - Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway
影响因子：3.545刊物：MEDIATORS OF INFLAMMATION发表日期：2019/1/17 - Deregulation of Regulatory T Cells in Acute-on-Chronic Liver Failure: A Rat Model
影响因子：3.232刊物：MEDIATORS OF INFLAMMATION发表日期：2017/1/15 - Ethanol extract of Pycnoporus sanguineus relieves the dextran sulfate sodium-induced experimental colitis by suppressing helper T cell-mediated inflammation via apoptosis induction
影响因子：4.545刊物：BIOMEDICINE & PHARMACOTHERAPY发表日期：2020/5/11 - Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivo
影响因子：2.806刊物：PLoS One发表日期：2017/5/8 - Fractalkine mediates lymphocyte inflammation and tubulointerstitial lesions by modifying the Treg/Th17 balance in lupus-prone MRL/lpr mice
影响因子：3.375刊物：American Journal of Translational Research发表日期：2020/10/15 - Impairment of Granzyme B-Producing Regulatory B Cells Correlates with Exacerbated Rheumatoid Arthritis
影响因子：6.429刊物：Frontiers in Immunology发表日期：2017/6/30 - Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study
影响因子：12.121刊物：Nature Communications发表日期：2020/4/20 - Abnormal expression of b10 cell frequencies: possible relation to pathogenesis and disease severity of aplastic anemia
影响因子：0.801刊物：Revista da Associacao Medica Brasileira发表日期：2019/6/3 - Correlation of gammadelta-T-cells, Th17 cells and IL-17 in peripheral blood of patients with allergic rhinitis.
影响因子：1.255刊物：ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY发表日期：2014/9/1 - MicroRNA-20a-5p suppresses IL-17 production by targeting OSM and CCL1 in patients with Vogt-Koyanagi-Harada disease
影响因子：3.384刊物：BRITISH JOURNAL OF OPHTHALMOLOGY发表日期：2018/2/1 - SHIP-1 Deficiency in AID+ B Cells Leads to the Impaired Function of B10 Cells with Spontaneous Autoimmunity
影响因子：4.856刊物：JOURNAL OF IMMUNOLOGY发表日期：2017/11/1 - AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis
影响因子：14.307刊物：JOURNAL OF EXPERIMENTAL MEDICINE发表日期：2021/3/12 - Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis
影响因子：10.892刊物：JOURNAL OF EXPERIMENTAL MEDICINE发表日期：2019/8/29 - Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer
影响因子：4.493刊物：Journal of Immunology Research发表日期：2022/5/28 - Prolonged exposure to high humidity and high temperature environment can aggravate influenza virus infection through intestinal flora and Nod/RIP2/NF-κB signaling pathway
影响因子：3.03刊物：VETERINARY MICROBIOLOGY发表日期：2020/10/16 - Helios expression in regulatory T cells promotes immunosuppression, angiogenesis and the growth of leukemia cells in pediatric acute lymphoblastic leukemia
影响因子：2.319刊物：LEUKEMIA RESEARCH发表日期：2018/2/14 - Forsythoside A Controls Influenza A Virus Infection and Improves the Prognosis by Inhibiting Virus Replication in Mice
影响因子：2.465刊物：MOLECULES发表日期：2016/4/26 - Increased Expression of Myeloid-Derived Suppressor Cells in Patients with HBV-Related Hepatocellular Carcinoma
影响因子：2.276刊物：Biomed Research International发表日期：2020/3/14 - Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration
影响因子：5.712刊物：Cell Communication and Signaling发表日期：2021/8/30 - Hydroxychloroquine sensitizes chronic myeloid leukemia cells to Vγ9Vδ2 T cell-mediated lysis independent of autophagy
影响因子：3.079刊物：INTERNATIONAL JOURNAL OF ONCOLOGY发表日期：2017/3/24 - Combined overexpression of four transcription factors promotes effector T cell dedifferentiation toward early phenotypes
影响因子：3.33刊物：IMMUNOGENETICS发表日期：2022/1/10 - Metabolic Reprogramming of CD4+ T Cells by Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuates Autoimmune Hepatitis Through Mitochondrial Protein Transfer
影响因子：6.6刊物：International Journal of Nanomedicine发表日期：2024-09-22 - Alcohol intake exacerbates experimental autoimmune prostatitis through gut microbiota driving cholesterol biosynthesis-mediated Th17 differentiation
影响因子：4.8刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：2024-07-18 - Unraveling CCL20's role by regulating Th17 cell chemotaxis in experimental autoimmune prostatitis
影响因子：4.3刊物：JOURNAL OF CELLULAR AND MOLECULAR MEDICINE发表日期：2024-05-27 - High glucose intake exacerbates experimental autoimmune prostatitis through mitochondrial reactive oxygen species-dependent TGF-β activation-mediated Th17 differentiation
影响因子：4.8刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：2024-02-22 - ECSIT facilitates memory CD8+ T cell development by mediating fumarate synthesis during viral infection and tumorigenesis
影响因子：17.3刊物：NATURE CELL BIOLOGY发表日期：2024-02-07 - Gasdermin D in macrophages drives orchitis by regulating inflammation and antigen presentation processes
影响因子：9刊物：EMBO Molecular Medicine发表日期：2024-01-02 - The CXCL10/CXCR3 axis regulates Th1 cell differentiation and migration in experimental autoimmune prostatitis through the PI3K/AKT pathway
影响因子：4.5刊物：Andrology发表日期：2023-12-14 - Multi-omic analysis reveals dynamic changes of three-dimensional chromatin architecture during T cell differentiation
影响因子：5.9刊物：Communications Biology发表日期：2023-07-24 - Salidroside affects the Th17/Treg cell balance in aplastic anemia via the STAT3/HIF-1α/RORγt pathway
影响因子：3.8刊物：REDOX REPORT发表日期：2023-07-13 - Impaired regulatory function of granzyme B-producing B cells against T cell inflammatory responses in lupus mice
影响因子：3.9刊物：Lupus Science & Medicine发表日期：2023-07-01 - An integrated bioinformatic investigation of focal adhesion-related genes in glioma followed by preliminary validation of COL1A2 in tumorigenesis
影响因子：5.2刊物：Aging-US发表日期：2023-06-22 - Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T?cell immunity
影响因子：29刊物：Cell Metabolism发表日期：2023-05-15 - Beta-adrenergic receptor blocker propranolol triggers anti-tumor immunity and enhances irinotecan therapy in mice colorectal cancer
影响因子：5刊物：EUROPEAN JOURNAL OF PHARMACOLOGY发表日期：2023-04-11 - 2-DG Re-Normalized IFN-γ Production in T Cells Excluding TEMRA Cells from Patients with Aplastic Anemia
影响因子：2.8刊物：IMMUNOLOGICAL INVESTIGATIONS发表日期：2023-03-29 - Alcohol intake exacerbates experimental autoimmune prostatitis through gut microbiota driving cholesterol biosynthesis-mediated Th17 differentiation
影响因子：4.8刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：2023-09-08 - Alcohol intake exacerbates experimental autoimmune prostatitis through gut microbiota driving cholesterol biosynthesis-mediated Th17 differentiation
影响因子：4.8刊物：INTERNATIONAL IMMUNOPHARMACOLOGY发表日期：http://2023-09-08 - Gasdermin D in Peripheral Myeloid Cells Drives Neuroinflammation in Experimental Autoimmune Encephalomyelitis
刊物：The Journal of experimental medicine 216, 2562-2581 (2019) - Mbd2-Mediated Th17 Differentiation in Severe Asthma Is Associated with Impaired Socs3 Expression
刊物：Experimental cell research 371, 196-204 (2018) - Nf-Κb-94ins/Del Attg Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia
刊物：Journal of immunology research 2018, 8170436 (2018)
刺激阻断剂操作常见问题查看更多刺激阻断剂操作步骤技术文章
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引用文献
1
Li S, Wu Y Q, Yang D X, et al. Gasdermin D in peripheral myeloid cells drives neuroinflammation in experimental autoimmune encephalomyelitis[J]. Journal of Experimental Medicine, 2019 （IF:10.9)
查看原文
2
Yu TS, Wang HY, Zhao YJ, et al. Abnormalities of bone marrow B cells and plasma cells in primary inmune thrombocytopenia[J]. Blood Advances, 2021, 5(20)：4087-4101 (IF=6.686)
查看原文
3
Wenjin S, Bing X, Aijun J, et al. MBD2-mediated Th17 differentiation in severe asthma is associated with impaired SOCS3 expression[J]. Experimental Cell Research, 2018, 371(1)： 196-204 (IF:3.309)
查看原文
4
Yu J, Hua M, Zhao X, et al. NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia[J]. 2018 (IF:3.298)
成为第一个“Ionomycin Calcium（离子霉素）” 的评价者
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