EK9162S

Human/Mouse/Rat TGF-β2 Standard (人/小鼠/大鼠转化生长因子β2 (TGF-β2) 标准品)

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¥280.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

  • 分子靶点：TGFB2, TGB-β2
  • 种属：人 (Human)
  • 试剂盒：EK9162
  • 保存：短期4℃保存，长期-20℃保存
  • 运输条件：4℃蓝冰运输

在售SKU:70-EK9162S

描述

本产品只包含标准品试剂，如需购买试剂盒请点击下图

商品名

Human/Mouse/Rat TGF-β2 Standard (人/小鼠/大鼠转化生长因子β2 (TGF-β2) 标准品)
组分

人/小鼠/大鼠TGF-β2 标准品
检测方法

双抗夹心法
样本类型

血清，血浆，细胞培养上清及其他生物学样本
板式

管
保存

短期4℃，长期-20℃保存
运输条件

4℃蓝冰运输

检测原理：本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人/小鼠/大鼠TGF-β2抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的TGF-β2与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中TGF-β2的浓度成正比。加入终止液终止反应，在450 nm波长(参考波长570 - 630 nm)测定吸光度值。

Human/Mouse/Rat TGF-β2 ELISA Kit (人/小鼠/大鼠转化生长因子β2 (TGF-β2) ELISA试剂盒) - 标准曲线
标准曲线

分子信息

概述人 TGFB2, TGB-β2 靶点信息

TGFB2 分子靶点信息概述

  • 分子名：TGFB2, transforming growth factor beta 2
  • 基因家族：Transforming growth factor beta family
  • 全称：prepro-transforming growth factor beta-2; transforming growth factor, beta 2

TGFB2 分子靶点综述

转化生长因子β2(TGF-β2)前体蛋白由19个氨基酸的信号肽、283个氨基酸的前区和112个氨基酸的成熟区组成。人TGF-β2成熟区与人TGF-β1和TGF-β3的同源性分别为71%和80%，与小鼠TGF-β2的同源性为97%。它可由各类细胞表达，包括破骨细胞、胸腺上皮细胞、角蛋白细胞、肝细胞、胃的主细胞和卫星细胞等。TGF-β2具有显著的种属交叉生物活性，如人TGF-β2对小鼠细胞具有活性，而猪TGF-β2对兔细胞具有活性等。TGF-β2具有4种基本活性：是大部分类型细胞的生长抑制因子；可增强细胞外基质的沉积；具有免疫抑制作用，抑制抗原递呈细胞表达IL-12和CD40L，上调IL-10分泌；在胚胎发育期表达于离散区域，如上皮、心肌、手足的软骨和骨骼、以及神经系统，提示其具有特异性的功能。

人 Human TGFB2 分子靶点信息

  • 分子名：TGFB2, transforming growth factor beta 2
  • 别称：
    • BSC-1 cell growth inhibitor
    • cetermin
    • G-TSF
    • glioblastoma-derived T-cell suppressor factor
    • LDS4
    • MGC116892
    • polyergin
    • prepro-transforming growth factor beta-2
    • TGF-beta-2
    • TGF-beta2
    • transforming growth factor beta-2
    • transforming growth factor beta-2 proprotein
    • transforming growth factor, beta 2
  • 基因序列：NCBI_Gene: 7042
  • 蛋白序列：UniProtKB: P61812

人 Human TGFB2靶点分子功能（预测）

Enables amyloid-beta binding activity; protein homodimerization activity; and transforming growth factor beta receptor binding activity. Involved in several processes, including animal organ development; cell surface receptor signaling pathway; and positive regulation of signal transduction. Located in collagen-containing extracellular matrix and extracellular space. Implicated in Loeys-Dietz syndrome 4 and colorectal cancer. Biomarker of colon carcinoma; colorectal cancer; and liver cirrhosis.

一文掌握ELISA实验显色判断、数据分析及标曲拟合

一文掌握ELISA实验显色判断、数据分析及标曲拟合 

血清OR血浆，哪个是ELISA的菜

血清OR血浆，哪个是ELISA的菜 

ELISA通关必备丨数据篇丨标准曲线不佳

ELISA通关必备丨数据篇丨标准曲线不佳 

ELISA通关必备丨操作篇丨常见问题及解决方案

ELISA通关必备丨操作篇丨常见问题及解决方案 

ELISA通关必备丨操作篇丨溶解与稀释标准品

ELISA通关必备丨操作篇丨溶解与稀释标准品 

ELISA通关必备丨样本篇丨不常见样本

ELISA通关必备丨样本篇丨不常见样本 

ELISA通关必备丨样本篇丨常见样本丨细胞

ELISA通关必备丨样本篇丨常见样本丨细胞 

ELISA通关必备丨如何选择试剂盒

ELISA通关必备丨如何选择试剂盒 

ELISA通关必备丨基础知识

ELISA通关必备丨基础知识 

真？假？ELISA试剂盒选择要小心

真？假？ELISA试剂盒选择要小心 

ELISA常见类型一 | 双抗夹心法，你要的都在这里！

ELISA常见类型一 | 双抗夹心法，你要的都在这里！ 

ELISA常见类型二 | 竞争法，五分钟搞定！

ELISA常见类型二 | 竞争法，五分钟搞定！ 

操作步骤

ELISA操作常见问题

一文掌握ELISA实验显色判断、数据分析及标曲拟合 

血清OR血浆，哪个是ELISA的菜 

ELISA通关必备丨数据篇丨标准曲线不佳 

ELISA通关必备丨操作篇丨常见问题及解决方案 

ELISA通关必备丨操作篇丨溶解与稀释标准品 

ELISA通关必备丨样本篇丨不常见样本 

ELISA通关必备丨样本篇丨常见样本丨细胞 

ELISA通关必备丨如何选择试剂盒 

ELISA通关必备丨基础知识 

真？假？ELISA试剂盒选择要小心 

ELISA常见类型一 | 双抗夹心法，你要的都在这里！ 

ELISA常见类型二 | 竞争法，五分钟搞定！ 

叮！联科向您投递了个ELISA实验操作干货包，请查收~ 

【视频】ELISA实验操作步骤演示视频教程 

ELISA 组织样本的处理—大鼠组织 

【视频】ELISA实验原理与常见问题分析 

查看更多ELISA操作相关问题

引用文献

文章目录[隐藏]


  1. Tumor associated neutrophils promote the metastasis of pancreatic ductal adenocarcinoma 

  2. In vivo effect of magnetic microspheres loaded with E2-a in the treatment of alveolar echinococcosis 

  3. Berberine-Loaded Carboxylmethyl Chitosan Nanoparticles Ameliorate DSS-Induced Colitis and Remodel Gut Microbiota in Mice 

  4. Endothelial cells promote triple-negative breast cancer cell metastasis via PAI-1 and CCL5 signaling 

  5. S-allylmercaptocysteine inhibits mucin overexpression and inflammation via MAPKs and PI3K-Akt signaling pathways in acute respiratory distress syndrome 

  6. Enhancing anti-tumor efficacy and immune memory by combining 3p-GPC-3 siRNA treatment with PD-1 blockade in hepatocellular carcinoma 

  7. Involvement of MM cell‑derived exosomes in T lymphocytes immune responses 

  8. Indigo Naturalis Alleviates Dextran Sulfate Sodium-Induced Colitis in Rats via Altering Gut Microbiota 

  9. Tetrahedral Framework Nucleic Acids Inhibit Skin Fibrosis via the Pyroptosis Pathway 

  10. Simultaneous solubilization and extended release of insoluble drug as payload in highly soluble particles of γ-cyclodextrin metal-organic frameworks 

  11. Peritoneal metastatic gastric carcinoma cells exhibit more malignant behavior when co-cultured with HMrSV5 cells 

  12. Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition 

  13. Hyperbaric Oxygen Improves the Survival and Angiogenesis of Fat Grafts after Autologous Fat Transplantation 

  14. ROS-responsive liposomes as an inhaled drug delivery nanoplatform for idiopathic pulmonary fibrosis treatment via Nrf2 signaling 

  15. HOXA10 mediates epithelial-mesenchymal transition to promote gastric cancer metastasis partly via modulation of TGFB2/Smad/METTL3 signaling axis 

  16. Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in chondrocytes 

  17. Bortezomib alleviates antibody-mediated rejection in kidney transplantation by facilitating Atg5 expression 

  18. Silica dust exposure induces pulmonary fibrosis through autophagy signaling 

  19. Plantaginis Semen polysaccharides ameliorate renal damage through regulating NLRP3 inflammasome in gouty nephropathy rats 

  20. Bone marrow mesenchymal stem cells modified with heme oxygenase-1 alleviate rejection of donation after circulatory death liver transplantation by inhibiting dendritic cell maturation in rats 

  21. Biomimetic micelles to accurately regulate the inflammatory microenvironment for glomerulonephritis treatment 

  22. Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance 

  23. Glucagon like peptide 2 has a positive impact on osteoporosis in ovariectomized rats 

  24. Aerobic Exercise Improves Pulmonary Fibrosis by Improving Insulin Resistance and Inflammation in Obese Mice 

  25. Bushen Jianpi Quyu Formula Alleviates Myelosuppression of an Immune-Mediated Aplastic Anemia Mouse Model via Inhibiting Expression of the PI3K/AKT/NF-κB Signaling Pathway 

  26. Macrophage Spheroids with Chronological Phenotype Shifting To Promote Therapeutic Angiogenesis in Critical Limb Ischemia 

  27. Targeting macrophagic 17β-HSD7 by fenretinide for the treatment of nonalcoholic fatty liver disease 

  28. miR-146a is directly regulated by STAT3 in human hepatocellular carcinoma cells and involved in anti-tumor immune suppression 

  29. The key role of macrophage depolarization in the treatment of COPD with ergosterol both in vitro and in vivo 

  30. Hybrid Biomaterial Initiates Refractory Wound Healing via Inducing Transiently Heightened Inflammatory Responses 

  31. Tenacissoside H promotes neurological recovery of cerebral ischaemia/reperfusion injury in mice by modulating inflammation and oxidative stress via TrkB pathway 

  32. Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis 

  33. Light-Triggered Efficient Sequential Drug Delivery of Biomimetic Nanosystem for Multimodal Chemo-, Antiangiogenic, and Anti-MDSC Therapy in Melanoma 

  34. Synergistic effects of low‑dose chemotherapy and T cells in renal cell carcinoma 

  35. Nanoengineered immunosuppressive therapeutics modulating M1/M2 macrophages into the balanced status for enhanced idiopathic pulmonary fibrosis therapy 

  36. Modified Gegen Qinlian Decoction Regulates Treg/Th17 Balance to Ameliorate DSS-Induced Acute Experimental Colitis in Mice by Altering the Gut Microbiota 

  37. Combination of Fruquintinib and Anti–PD-1 for the Treatment of Colorectal Cancer 

  38. Bu-Shen-Yi-Qi formula ameliorates airway remodeling in murine chronic asthma by modulating airway inflammation and oxidative stress in the lung 

  39. Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice 

  40. Tumor Cell-Derived Exosomal miR-770 Inhibits M2 Macrophage Polarization via Targeting MAP3K1 to Inhibit the Invasion of Non-small Cell Lung Cancer Cells 

  41. Dynamics of Th9 cells and their potential role in immunopathogenesis of murine schistosomiasis 

  42. A bioinspired and high-strengthed hydrogel for regeneration of perforated temporomandibular joint disc: Construction and pleiotropic immunomodulatory effects 

  43. Chemical Components and Hepatoprotective Mechanism of Xwak Granule in Mice Treated with Acute Alcohol 

  44. SS-31 Modification Inhibits the Proinflammatory Effect on Macrophages Induced by Superparamagnetic Iron Oxide Nanoparticles 

  45. Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis 

  46. Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice 

  47. HMGB1 aggravates lipopolysaccharide-induced acute lung injury through suppressing the activity and function of Tregs 

  48. MiR-181a regulates CD4+ T cell activation and differentiation by targeting IL-2 in the pathogenesis of myasthenia gravis 

  49. TL1A modulates the severity of colitis by promoting Th9 differentiation and IL-9 secretion 

  50. IFNA-AS1 regulates CD4+ T cell activation in myasthenia gravis though HLA-DRB1 

  51. Perdurable PD-1 blockage awakes anti-tumor immunity suppressed by precise chemotherapy 

  52. Gegen Qinlian decoction enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by remodelling the gut microbiota and the tumour microenvironment 

  53. Effects of ceftriaxone-induced intestinal dysbacteriosis on regulatory T cells validated by anaphylactic mice 

  54. Melatonin Suppresses LPS-Induced Oxidative Stress in Dendritic Cells for Inflammatory Regulation via the Nrf2/HO-1 Axis 

  55. Edible Bird’s Nest Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in C57BL/6J Mice by Restoring the Th17/Treg Cell Balance 

  56. ANG II facilitated CD11+Ly6Chi cells reprogramming into M1-like macrophage through Erk1/2 or p38-Stat3 pathway and involved in EAM 

  57. Green Tea Derivative Driven Smart Hydrogels with Desired Functions for Chronic Diabetic Wound Treatment 

  58. Growth factors-based platelet lysate rejuvenates skin against ageing through NF-κB signalling pathway: In vitro and in vivo mechanistic and clinical studies 

  59. Tanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer 

  60. Vitamin D deficiency is associated with thyroid autoimmunity: results from an epidemiological survey in Tianjin, China 

  61. The Effect of Entecavir Therapy on Immune Status in Chronic Hepatitis B Patients 

  62. Alteration of Myeloid-Derived Suppressor Cells, Chronic Inflammatory Cytokines, and Exosomal miRNA Contribute to the Peritoneal Immune Disorder of Patients With Endometriosis 

  63. Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment 

  64. Total extract of Xin Jia Xuan Bai Cheng Qi decoction inhibits pulmonary fibrosis via the TGF-β/Smad signaling pathways in vivo and in vitro 

  65. Low Ratio of Treg to Th17 Cells After 36 Weeks of Telbivudine Therapy Predict HBeAg Seroconversion 

  66. Targeting the class IA PI3K isoforms p110α/δ attenuates heart allograft rejection in mice by suppressing the CD4+ T lymphocyte response 

  67. Gut Dysbiosis Contributes to the Imbalance of Treg and Th17 Cells in Graves’ Disease Patients by Propionic Acid 

  68. Myeloid-derived suppressor cell cytokine secretion as prognostic factor in myelodysplastic syndromes 

  69. Circular RNA circWWC3 augments breast cancer progression through promoting M2 macrophage polarization and tumor immune escape via regulating the expression and secretion of IL-4 

  70. Glucose Metabolism Reprogramming of Regulatory T Cells in Concanavalin A-Induced Hepatitis 

  71. Reduced expression of CYLD promotes cell survival and inflammation in gefitinib-treated NSCLC PC-9 cells: Targeting CYLD may be beneficial for acquired resistance to gefitinib therapy 

  72. Impaired myeloid-derived suppressor cells are associated with recurrent implantation failure: A case-control study 

  73. Distribution of Th17 cells and Foxp3-expressing T cells in tumor-infiltrating lymphocytes in patients with uterine cervical cancer 

  74. Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis: a randomized, double-blind, placebo-controlled phase 2 trial 

  75. Expression and significance of peripheral myeloid-derived suppressor cells in chronic hepatitis B patients 

  76. MiR-340 suppresses CCl4-induced acute liver injury through exerting anti-inflammation targeting Sigirr 

  77. Mesenchymal Stem Cells Improve Depressive Disorder via Inhibiting the Inflammatory Polarization of Microglia 

  78. Network pharmacology and experimental validation to explore the anti-aging mechanism of action of betulinic acid 

  79. Reconstituted CD74+ NK cells trigger chronic graft versus host disease after allogeneic bone marrow transplantation 

  80. Fraxinellone alleviates colitis-related intestinal fibrosis by blocking the circuit between PD-1+ Th17 cells and fibroblasts 

  81. Spatiotemporal modulation of immune microenvironment via composite hydrogel brakes for diabetic wound healing 

  82. An Immune-Regulating Polysaccharide Hybrid Hydrogel with Mild Photothermal Effect and Anti-Inflammatory for Accelerating Infected Wound Healing 

  83. DPSCs regulate epithelial-T cell interactions in oral submucous fibrosis 

  84. Macrophage-Derived Nanosponges Adsorb Cytokines and Modulate Macrophage Polarization for Renal Cell Carcinoma Immunotherapy 

  85. Role of macrophage polarization in periodontitis promoting atherosclerosis 

  86. Design, synthesis, and biological evaluation of first-in-class FABP1 inhibitors for the treatment of NASH 

  87. The miR-25802/KLF4/NF-κB signaling axis regulates microglia-mediated neuroinflammation in Alzheimer’s disease 

  88. Platelet Membrane Nanocarriers Cascade Targeting Delivery System to Improve Myocardial Remodeling Post Myocardial Ischemia–Reperfusion Injury 

  89. Innate immune responsive inflammation in development of progressive myopia 

  90. Macrophage-specific FGFR1 deletion alleviates high-fat-diet-induced liver inflammation by inhibiting the MAPKs/TNF pathways 

  91. Hollow Copper Sulfide Photothermal Nanodelivery Platform Boosts Angiogenesis of Diabetic Wound by Scavenging Reactive Oxygen Species 

  92. Biomimetic Nanoplatform for Dual-Targeted Clearance of Activated and Senescent Cancer-Associated Fibroblasts to Improve Radiation Resistance in Breast Cancer 

  93. Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer 

  94. IL4I1 in M2-like macrophage promotes glioma progression and is a promising target for immunotherapy 

  95. Hollow CuS immobilized in polysaccharide hydrogel promotes photothermally-driven vascularization 

  96. An insect sclerotization-inspired antifouling armor on biomedical devices combats thrombosis and embedding 

  97. Synergetic regulation of cancer cells and exhausted T cells to fight cold tumors with a fluorinated EGCG-based nanocomplex 

  98. Rosmarinic acid nanomedicine for rheumatoid arthritis therapy: Targeted RONS scavenging and macrophage repolarization 

  99. Effects and mechanism of Kedaling tablets for atherosclerosis treatment based on network pharmacology, molecular docking and experimental study 

  100. Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization 

  101. Repolarization of Inflammation-Associated Macrophages by Dual Drug-Loaded Liposomes for Acute Lung Sepsis Antibacterial and Anti-inflammatory Therapy 

  102. An injectable signal-amplifying device elicits a specific immune response against malignant glioblastoma 

  103. Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1 

  104. Sequence Variation of Candida albicans Sap2 Enhances Fungal Pathogenicity via Complement Evasion and Macrophage M2-Like Phenotype Induction 

  105. Tailored Apoptotic Vesicle Delivery Platform for Inflammatory Regulation and Tissue Repair to Ameliorate Ischemic Stroke 

  106. Multifunctional chondroitin sulfate based hydrogels for promoting infected diabetic wounds healing by chemo-photothermal antibacterial and cytokine modulation 

  107. In vivo effects of low dose prenatal bisphenol A exposure on adiposity in male and female ICR offspring 

  108. Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro 

  109. Temperature sensitive liposome based cancer nanomedicine enables tumour lymph node immune microenvironment remodelling 

  110. Inhibition of Toll-Like Receptor 4 Signaling Pathway Accelerates the Repair of Avascular Necrosis of Femoral Epiphysis through Regulating Macrophage Polarization in Perthes Disease 

  111. Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1α 

  112. Regulating T-cell metabolic reprogramming and blocking PD-1 co-promote personalized postoperative autologous nanovaccines 

  113. Functional Titanium Substrates Synergetic Photothermal Therapy for Enhanced Antibacterial and Osteogenic Performance via Immunity Regulation 

  114. Changes within Liver Accounts for Fatty Acids Decrease in the Blood of Rats with Adjuvant-Induced Arthritis 

  115. Panax notoginseng saponins (PNS) attenuate Th17 cell differentiation in CIA mice via inhibition of nuclear PKM2-mediated STAT3 phosphorylation 

  116. Procoxacin bidirectionally inhibits osteoblastic and osteoclastic activity in bone and suppresses bone metastasis of prostate cancer 

  117. Treg-targeted efficient-inducible platform for collagen-induced arthritis treatment 

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