Human IL-17A High Sensitivity Standard (人白介素17A 高敏标准品)
¥180.00
因产品会迭代升级,具体实验步骤请按纸质版说明书操作
描述
文章目录[隐藏]
本产品只包含标准品试剂,如需购买试剂盒请点击下图
-
- EK117HS
- 高敏试剂盒
Human IL-17A High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00
商品名 |
Human IL-17A High Sensitivity Standard (人白介素17A 高敏标准品) |
---|---|
组分 |
人IL-17高敏标准品 |
检测方法 |
双抗夹心法 |
样本类型 |
血清,血浆,细胞培养上清及其他生物学样本 |
板式 |
管 |
保存 |
短期4℃,长期-20℃保存 |
运输条件 |
4℃蓝冰运输 |
检测原理:本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人IL-17A抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体,经过孵育,样本中存在的IL-17A与固相抗体和检测抗体结合。洗涤去除未结合的物质后,加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后,加入显色底物TMB,避光显色。颜色反应的深浅与样本中IL-17A的浓度成正比。加入终止液终止反应,在450 nm波长(参考波长570 - 630 nm)测定吸光度值。
分子信息
IL17A 分子靶点信息概述
- 分子名:IL17A, interleukin 17A
- 基因家族:Interleukins
- 别名:IL-17A; IL-17
- 曾用名:CTLA8; IL17
- 全称:cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
IL17A 分子靶点综述
IL-17主要由Th17型细胞产生,是目前已发现的30余种白细胞介素中的一员,按序号排在第17位。该家族包括6个成员配体(IL-17A ~ IL-17F)和5个受体(IL-17RA ~ IL-17RD和SEF)。IL-17是一种主要由活化的T细胞产生的致炎细胞因子,可以促进T细胞的激活和刺激上皮细胞、内皮细胞、成纤维细胞产生多种细胞因子,从而导致炎症的产生。
人 Human IL17A 分子靶点信息
- 分子名:IL17A, interleukin 17A
- 别称:
- CTLA-8
- CTLA8
- cytotoxic T-lymphocyte-associated antigen 8
- cytotoxic T-lymphocyte-associated protein 8
- cytotoxic T-lymphocyte-associated serine esterase 8
- IL-17
- IL-17A
- IL17
- ILA17
- interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
- interleukin-17
- interleukin-17A
- 基因序列:NCBI_Gene: 3605
- 蛋白序列:UniProtKB: Q16552
人 Human IL17A靶点分子功能(预测)
Predicted to enable cytokine activity; protein heterodimerization activity; and protein homodimerization activity. Involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of cytokine production; and positive regulation of osteoclast differentiation. Acts upstream of or within positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular region. Implicated in Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); macular degeneration; and rhinitis (multiple). Biomarker of several diseases, including acne; autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and rhinitis (multiple).
操作步骤
文章目录[隐藏]
- ELISA操作常见问题
- 血清OR血浆,哪个是ELISA的菜 
- ELISA通关必备丨数据篇丨标准曲线不佳 
- ELISA通关必备丨操作篇丨常见问题及解决方案 
- ELISA通关必备丨操作篇丨溶解与稀释标准品 
- ELISA通关必备丨样本篇丨不常见样本 
- ELISA通关必备丨样本篇丨常见样本丨细胞 
- ELISA通关必备丨如何选择试剂盒 
- ELISA通关必备丨基础知识 
- 真?假?ELISA试剂盒选择要小心 
- ELISA常见类型一 | 双抗夹心法,你要的都在这里! 
- ELISA常见类型二 | 竞争法,五分钟搞定! 
- 叮!联科向您投递了个ELISA实验操作干货包,请查收~ 
- 【视频】ELISA实验操作步骤演示视频教程 
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- 【视频】ELISA实验原理与常见问题分析 
- 查看更多ELISA操作相关问题
ELISA操作常见问题
查看更多ELISA操作相关问题
引用文献
文章目录[隐藏]
- RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer 
- Involvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome 
- RAS-association domain family 1A regulates the abnormal cell proliferation in psoriasis via inhibition of Yes-associated protein 
- Vitamin D deficiency is associated with thyroid autoimmunity: results from an epidemiological survey in Tianjin, China 
- Elevated Peripheral Frequencies of Th22 Cells: A Novel Potent Participant in Obesity and Type 2 Diabetes 
- CD4+/CD8+ mucosa-associated invariant T cells foster the development of endometriosis: a pilot study 
- Vitamin D Deficiency Contributes to the Reduction and Impaired Function of Naïve Regulatory T Cell in Chronic Heart Failure 
- Differentiation of T-helper cells in distinct phases of atopic dermatitis involves Th1/Th2 and Th17/Treg 
- Immunomodulatory effects of platelets on the severity of hand, foot, and mouth disease infected with enterovirus 71 
- Imbalance of Th17, Treg, and helper innate lymphoid cell in the peripheral blood of patients with rheumatoid arthritis 
- Metabolic Enzyme Triosephosphate Isomerase 1 and Nicotinamide Phosphoribosyltransferase, Two Independent Inflammatory Indicators in Rheumatoid Arthritis: Evidences From Collagen-Induced Arthritis and Clinical Samples 
- Triptolide inhibits Th17 differentiation via controlling PKM2-mediated glycolysis in rheumatoid arthritis 
- MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity 
- Total extract of Xin Jia Xuan Bai Cheng Qi decoction inhibits pulmonary fibrosis via the TGF-β/Smad signaling pathways in vivo and in vitro 
- Low Ratio of Treg to Th17 Cells After 36 Weeks of Telbivudine Therapy Predict HBeAg Seroconversion 
- Basal level of Th17 immune response is not enhanced in aplastic amemia 
- Involvement of interleukin-21 in the pathophysiology of aplastic anemia 
- Targeting the class IA PI3K isoforms p110α/δ attenuates heart allograft rejection in mice by suppressing the CD4+ T lymphocyte response 
- Glycolysis aggravates methotrexate toxicity by fueling RFC1-controlled intestinal absorption in rheumatic rats 
- Tonsillar Microbiome-Derived Lantibiotics Induce Structural Changes of IL-6 and IL-21 Receptors and Modulate Host Immunity 
- Changes of Th17/Tc17 and Th17/Treg cells in endometrial carcinoma 
- Fibrinogen-Like Protein 1 as a Novel Biomarker of Psoriasis Severity 
- Berberine inhibits dendritic cells differentiation in DSS-induced colitis by promoting Bacteroides fragilis 
- Participation of Increased Circulating MAIT Cells in Lung Cancer: a Pilot Study 
- Distribution of Th17 cells and Foxp3-expressing T cells in tumor-infiltrating lymphocytes in patients with uterine cervical cancer 
- Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis: a randomized, double-blind, placebo-controlled phase 2 trial 
- A metagenome-wide association study of the gut microbiota in recurrent aphthous ulcer and regulation by thalidomide. 
- Interleukin-25 is upregulated in patients with systemic lupus erythematosus and ameliorates murine lupus by inhibiting inflammatory cytokine production 
- Colorectal Cancer Progression Is Associated with Accumulation of Th17 Lymphocytes in Tumor Tissues and Increased Serum Levels of Interleukin-6 
- Amelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17?cells 
- A citrullinated antigenic vaccine in treatment of autoimmune arthritis 
- Gut Microbiota Disorder Contributes to the Production of IL-17A That Exerts Chemotaxis via Binding to IL-17RA in Endometriosis 
- Effects of silencing NLRP3 gene on proliferation of psoriasis-like HaCaT cells and expressions of cytokines 
- Small extracellular vesicles derived from human mesenchymal stem cells prevent Th17-dominant neutrophilic airway inflammation via immunoregulation on Th17 cells 
- DPSCs regulate epithelial-T cell interactions in oral submucous fibrosis 
- Periodontitis aggravates COPD through the activation of γδ T cell and M2 macrophage 
- Characteristics of Serum Autoantibody Repertoire and Immune Subgroup Variation of Tuberculosis-Associated Obstructive Pulmonary Disease 
- Fe-curcumin nanozyme-mediated immunosuppression and anti-inflammation in experimental autoimmune uveitis 
- SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sj?gren's syndrome 
- BMI-specific inflammatory response to phthalate exposure in early pregnancy: findings from the TMCHESC study 
- A role of NR4A2 in Graves’ disease: regulation of Th17/Treg 
- Hyperoside alleviates postmenopausal osteoporosis via regulating miR-19a-5p/IL-17A axis 
- Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro 
- MicroRNA-143-3p ameliorates collagen-induced arthritis by polarizing naive CD4+T cells into Treg cells 
- Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses 
- A metagenome-wide association study of the gut microbiota in recurrent aphthous ulcer and regulation by thalidomide 
RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer 
Involvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome 
RAS-association domain family 1A regulates the abnormal cell proliferation in psoriasis via inhibition of Yes-associated protein 
Vitamin D deficiency is associated with thyroid autoimmunity: results from an epidemiological survey in Tianjin, China 
Elevated Peripheral Frequencies of Th22 Cells: A Novel Potent Participant in Obesity and Type 2 Diabetes 
CD4+/CD8+ mucosa-associated invariant T cells foster the development of endometriosis: a pilot study 
Vitamin D Deficiency Contributes to the Reduction and Impaired Function of Naïve Regulatory T Cell in Chronic Heart Failure 
Differentiation of T-helper cells in distinct phases of atopic dermatitis involves Th1/Th2 and Th17/Treg 
Immunomodulatory effects of platelets on the severity of hand, foot, and mouth disease infected with enterovirus 71 
Imbalance of Th17, Treg, and helper innate lymphoid cell in the peripheral blood of patients with rheumatoid arthritis 
Metabolic Enzyme Triosephosphate Isomerase 1 and Nicotinamide Phosphoribosyltransferase, Two Independent Inflammatory Indicators in Rheumatoid Arthritis: Evidences From Collagen-Induced Arthritis and Clinical Samples 
Triptolide inhibits Th17 differentiation via controlling PKM2-mediated glycolysis in rheumatoid arthritis 
MicroRNA-26b-5p alleviates murine collagen-induced arthritis by modulating Th17 cell plasticity 
Total extract of Xin Jia Xuan Bai Cheng Qi decoction inhibits pulmonary fibrosis via the TGF-β/Smad signaling pathways in vivo and in vitro 
Low Ratio of Treg to Th17 Cells After 36 Weeks of Telbivudine Therapy Predict HBeAg Seroconversion 
Basal level of Th17 immune response is not enhanced in aplastic amemia 
Involvement of interleukin-21 in the pathophysiology of aplastic anemia 
Targeting the class IA PI3K isoforms p110α/δ attenuates heart allograft rejection in mice by suppressing the CD4+ T lymphocyte response 
Glycolysis aggravates methotrexate toxicity by fueling RFC1-controlled intestinal absorption in rheumatic rats 
Tonsillar Microbiome-Derived Lantibiotics Induce Structural Changes of IL-6 and IL-21 Receptors and Modulate Host Immunity 
Changes of Th17/Tc17 and Th17/Treg cells in endometrial carcinoma 
Fibrinogen-Like Protein 1 as a Novel Biomarker of Psoriasis Severity 
Berberine inhibits dendritic cells differentiation in DSS-induced colitis by promoting Bacteroides fragilis 
Participation of Increased Circulating MAIT Cells in Lung Cancer: a Pilot Study 
Distribution of Th17 cells and Foxp3-expressing T cells in tumor-infiltrating lymphocytes in patients with uterine cervical cancer 
Efficacy and safety of low-dose interleukin-2 in combination with methotrexate in patients with active rheumatoid arthritis: a randomized, double-blind, placebo-controlled phase 2 trial 
A metagenome-wide association study of the gut microbiota in recurrent aphthous ulcer and regulation by thalidomide. 
Interleukin-25 is upregulated in patients with systemic lupus erythematosus and ameliorates murine lupus by inhibiting inflammatory cytokine production 
Colorectal Cancer Progression Is Associated with Accumulation of Th17 Lymphocytes in Tumor Tissues and Increased Serum Levels of Interleukin-6 
Amelioration of immunoglobulin A vasculitis by suppression of the pathological expansion of T follicular helper 17?cells 
A citrullinated antigenic vaccine in treatment of autoimmune arthritis 
Gut Microbiota Disorder Contributes to the Production of IL-17A That Exerts Chemotaxis via Binding to IL-17RA in Endometriosis 
Effects of silencing NLRP3 gene on proliferation of psoriasis-like HaCaT cells and expressions of cytokines 
Small extracellular vesicles derived from human mesenchymal stem cells prevent Th17-dominant neutrophilic airway inflammation via immunoregulation on Th17 cells 
DPSCs regulate epithelial-T cell interactions in oral submucous fibrosis 
Periodontitis aggravates COPD through the activation of γδ T cell and M2 macrophage 
Characteristics of Serum Autoantibody Repertoire and Immune Subgroup Variation of Tuberculosis-Associated Obstructive Pulmonary Disease 
Fe-curcumin nanozyme-mediated immunosuppression and anti-inflammation in experimental autoimmune uveitis 
SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sj?gren's syndrome 
BMI-specific inflammatory response to phthalate exposure in early pregnancy: findings from the TMCHESC study 
A role of NR4A2 in Graves’ disease: regulation of Th17/Treg 
Hyperoside alleviates postmenopausal osteoporosis via regulating miR-19a-5p/IL-17A axis 
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro 
MicroRNA-143-3p ameliorates collagen-induced arthritis by polarizing naive CD4+T cells into Treg cells 
Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses 
A metagenome-wide association study of the gut microbiota in recurrent aphthous ulcer and regulation by thalidomide 
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