AP101C

Annexin V-FITC/PI Apoptosis Kit (C6专用)

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¥630.00 – ¥1,280.00

在售SKU:70-AP101C-100, 70-AP101C-60, 70-AP101C-30, 凋亡, 细胞凋亡, 凋亡试剂盒, 细胞凋亡试剂盒, 凋亡检测, 细胞凋亡检测, 凋亡检测试剂盒, 细胞凋亡检测试剂盒, Annexin V, Annexin, Apoptosis, PI

描述

产品简介

Annexin V(或 Annexin A5)为胞内蛋白膜联蛋白家族成员，以钙依赖的方式与磷脂酰丝氨酸(PS)结合。PS 存在于正常细胞浆膜的内层，但在凋亡早期，膜不对称性丧失，PS易位至细胞表面。荧光标记的 Annexin V 可与之特异性结合，表明该细胞为凋亡细胞。本试剂盒仅需 15 分钟即可染色，快速方便。

此凋亡试剂盒针对BD的C6仪器进行优化，可方便调节补偿。

产品特点

  • 操作简便，15分钟即可完成染色；
  • 分群清晰，结果稳定可靠；
  • 独家搭配阳性质控液，补偿调节不再困难；
  • 针对BD的C6仪器进行优化，方便操作。

结果示例


a.阳性质控液处理的HL60细胞，Annexin V-FITC单染
b.阳性质控液处理的HL60细胞，PI单染
c.未经喜树碱诱导的HL60细胞，Annexin V-FITC/PI双染
d.5 μM喜树碱诱导的HL60细胞，Annexin V-FITC/PI双染

试剂盒组分

引用文献

文章目录[隐藏]


  1. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy 

  2. LDHA Suppression Altering Metabolism Inhibits Tumor Progress by an Organic Arsenical 

  3. Organic arsenicals target thioredoxin reductase followed by oxidative stress and mitochondrial dysfunction resulting in apoptosis 

  4. Oxidative stress-mediated intrinsic apoptosis in human promyelocytic leukemia HL-60 cells induced by organic arsenicals 

  5. NOVA1 promotes NSCLC proliferation and invasion by activating Wnt/β-catenin signaling 

  6. Klotho downregulation contributes to myocardial damage of cardiorenal syndrome in sepsis 

  7. Fibroblast transdifferentiation promotes conversion of M1 macrophages and replenishment of cardiac resident macrophages following cardiac injury in mice 

  8. Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways 

  9. Sustained release of Ganoderma lucidum antitumor drugs using a sandwich structured material prepared by electrospinning 

  10. Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells 

  11. miR-182 selectively targets HOXA10 in goat endometrial epithelium cells in vitro 

  12. Immunomodulatory effect of thymopentin on lymphocytes from supramammary lymph nodes of dairy cows 

  13. Pinin promotes tumor progression via activating CREB through PI3K/AKT and ERK/MAPK pathway in prostate cancer 

  14. Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B 

  15. HN1L is essential for cell growth and survival during nucleopolyhedrovirus infection in silkworm, Bombyx mori 

  16. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70 

  17. LncRNA882 regulates leukemia inhibitory factor (LIF) by sponging miR-15b in the endometrial epithelium cells of dairy goat 

  18. Blockade of the mTOR signaling pathway with rapamycin ameliorates aristolochic acid nephropathy 

  19. Characterization and anti-uterine tumor effect of extract from Prunella vulgaris L. 

  20. Therapeutic potential of transplanted placental mesenchymal stem cells in treating Chinese miniature pigs with acute liver failure 

  21. The miR155HG/miR-185/ANXA2 loop contributes to glioblastoma growth and progression 

  22. Long non-coding RNA MACC1-AS1 promoted pancreatic carcinoma progression through activation of PAX8/NOTCH1 signaling pathway 

  23. MiR-206 suppresses the deterioration of intrahepatic cholangiocarcinoma and promotes sensitivity to chemotherapy by inhibiting interactions with stromal CAFs 

  24. Alkaloid Dimers Isolated from Thalictrum baicalense Have Antitumor Activities 

  25. Effects of PLIN1 Gene Knockout on the Proliferation, Apoptosis, Differentiation and Lipolysis of Chicken Preadipocytes 

  26. Melatonin inhibits embryonic rat H9c2 cells growth through induction of apoptosis and cell cycle arrest via PI3K-AKT signaling pathway 

  27. A dual-targeted molecular therapy of PP242 and cetuximab plays an anti-tumor effect through EGFR downstream signaling pathways in colorectal cancer 

  28. The Inhibition of Adipose-Derived Stem Cells on the Invasion of Keloid Fibroblasts. 

  29. Folic acid modified UiO-66 nano drug carrier for combination therapy 

  30. Molecular characterization of a novel GSTO2 of Fasciola hepatica and its roles in modulating murine macrophages 

  31. Effects of triptolide on bone marrow‑derived mesenchymal stem cells from patients with multiple myeloma 

  32. Downregulation of HIF-2α Enhances Apoptosis and Limits Invasion in Human Placental JEG-3 Trophoblast Cells 

  33. Cuprous oxide nanoparticles inhibit the growth of cervical carcinoma by inducing autophagy 

  34. Biodegradable Nanocatalyst with Self-Supplying Fenton-like Ions and H2O2 for Catalytic Cascade-Amplified Tumor Therapy 

  35. LRIG1 enhances the radiosensitivity of radioresistant human glioblastoma U251 cells via attenuation of the EGFR/Akt signaling pathway 

  36. MicroRNA‑206 contributes to the progression of steroid‑induced avascular necrosis of the femoral head by inducing osteoblast apoptosis by suppressing programmed cell death 4 

  37. Bone-seeking nanoplatform co-delivering cisplatin and zoledronate for synergistic therapy of breast cancer bone metastasis and bone resorption 

  38. Epithelial cell -derived microvesicles: A safe delivery platform of CRISPR/Cas9 conferring synergistic anti-tumor effect with sorafenib 

  39. On-Demand Generation of Peroxynitrite from an Integrated Two-Dimensional System for Enhanced Tumor Therapy 

  40. Cancerous Inhibitor of PP2A Silencing Inhibits Proliferation and Promotes Apoptosis in Human Multiple Myeloma Cells 

  41. microRNA-1297 Inhibits the Growth and Metastasis of Colorectal Cancer by Suppressing Cyclin D2 Expression 

  42. Matrine induces papillary thyroid cancer cell apoptosis in vitro and suppresses tumor growth in vivo by downregulating miR-182-5p 

  43. JLX001 Ameliorates Ischemia/Reperfusion Injury by Reducing Neuronal Apoptosis via Down-Regulating JNK Signaling Pathway 

  44. A smart fluorescence nanoprobe for the detection of cellular alkaline phosphatase activity and early osteogenic differentiation 

  45. LINC00365 promotes colorectal cancer cell progression through the Wnt/β-catenin signaling pathway 

  46. SNP rs4971059 predisposes to breast carcinogenesis and chemoresistance via TRIM46-mediated HDAC1 degradation 

  47. Comparison of carbon-sulfur and carbon-amine bond in therapeutic drug: 4β-S-aromatic heterocyclic podophyllum derivatives display antitumor activity 

  48. Selective Intratumoral Drug Release and Simultaneous Inhibition of Oxidative Stress by a Highly Reductive Nanosystem and Its Application as an Anti-tumor Agent 

  49. Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combined with ultrasound on the growth of squamous cell carcinoma of the esophagus 

  50. Dual actions of albumin packaging and tumor targeting enhance the antitumor efficacy and reduce the cardiotoxicity of doxorubicin in vivo 

  51. Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes 

  52. Graphene Quantum Dots Induce Autophagy and Reveal Protection Against Hydrogen Peroxide-Induced Oxidative Stress Injury 

  53. Pharmic Activation of PKG2 Alleviates Diabetes-Induced Osteoblast Dysfunction by Suppressing PLCβ1-Ca2+-Mediated Endoplasmic Reticulum Stress 

  54. E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter 

  55. 2β, 3β, 23-trihydroxy-urs-12-ene-28-olic acid (TUA) isolated from Actinidia chinensis Radix inhibits NCI-H460 cell proliferation by decreasing NF-κB expression 

  56. CRA(Crosolic Acid) isolated from Actinidia valvata Dunn.Radix induces apoptosis of human gastric cancer cell line BGC823 in vitro via down-regulation of the NF-κB pathway 

  57. Nanosystem composed with MSNs, gadolinium, liposome and cytotoxic peptides for tumor theranostics 

  58. Novel conjugates of endoperoxide and 4-anilinoquinazoline induce myeloma cell apoptosis by inhibiting the IGF1-R/AKT/mTOR signaling pathway 

  59. Gemcitabine-Loaded Albumin Nanoparticle Exerts An Antitumor Effect on Gemcitabine-Resistant Pancreatic Cancer Cells Induced by MDR1 and MRP1 Overexpression in Vitro 

  60. HOXA13, Negatively Regulated by miR-139-5p, Decreases the Sensitivity of Gastric Cancer to 5-Fluorouracil Possibly by Targeting ABCC4 

  61. Asiaticoside alleviates cardiomyocyte apoptosis and oxidative stress in myocardial ischemia/reperfusion injury via activating the PI3K-AKT-GSK3β pathway in vivo and in vitro 

  62. Transcriptomic analysis of cells in response to EV71 infection and 2Apro as a trigger for apoptosis via TXNIP gene 

  63. Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G0/G1 Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation 

  64. Glypican 2 regulates cell proliferation and metastasis in thyroid cancer cells 

  65. Ethyl acetate fraction of Terminalia bellirica fruit inhibits rat hepatic stellate cell proliferation and induces apoptosis 

  66. Iron overload promotes erythroid apoptosis through regulating HIF-1a/ROS signaling pathway in patients with myelodysplastic syndrome 

  67. Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis 

  68. Emodin promotes the arrest of human lymphoma Raji cell proliferation through the UHRF1‑DNMT3A‑∆Np73 pathways 

  69. Suppression of USP7 induces BCR-ABL degradation and chronic myelogenous leukemia cell apoptosis 

  70. Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis 

  71. Mitochondria-Targeted Peptide MTP-131 Alleviates Mitochondrial Dysfunction and Oxidative Damage in Human Trabecular Meshwork Cells 

  72. Metformin synergistically enhances antitumor activity of cisplatin in gallbladder cancer via the PI3K/AKT/ERK pathway 

  73. TGX-221 inhibits proliferation and induces apoptosis in human glioblastoma cells 

  74. Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ β-catenin pathway 

  75. Chondrocyte-derived Exosomal miR-195 Inhibits Osteosarcoma Cell Proliferation and Anti-Apoptotic by Targeting KIF4A in vitro and in vivo 

  76. HSP47 is associated with the prognosis of laryngeal squamous cell carcinoma by inhibiting cell viability and invasion and promoting apoptosis 

  77. ZnO Quantum Dots Induced Oxidative Stress and Apoptosis in HeLa and HEK-293T Cell Lines 

  78. Effects of phycoerythrin from Gracilaria lemaneiformis in proliferation and apoptosis of SW480 cells 

  79. Curcumin: a calixarene derivative micelle potentiates anti-breast cancer stem cells effects in xenografted, triple-negative breast cancer mouse models 

  80. miR-454 regulates triglyceride synthesis in bovine mammary epithelial cells by targeting PPAR-γ 

  81. Grape seed proanthocyanidins inhibit the proliferation, migration and invasion of tongue squamous cell carcinoma cells through suppressing the protein kinase B/nuclear factor-κB signaling pathway 

  82. Effects of different concentrations of metformin on osteoclast differentiation and apoptosis and its mechanism 

  83. Lefty A protein inhibits TGF-β1-mediated apoptosis in human renal tubular epithelial cells 

  84. Norcantharidin alone or in combination with crizotinib induces autophagic cell death in hepatocellular carcinoma by repressing c-Met-mTOR signaling 

  85. Preparation and Characterization of Fullerene (C60) Amino Acid Nanoparticles for Liver Cancer Cell Treatment 

  86. A cabazitaxel liposome for increased solubility, enhanced antitumor effect and reduced systemic toxicity 

  87. Pituitary tissue-specific miR-7a-5p regulates FSH expression in rat anterior adenohypophyseal cells 

  88. SCRIB Promotes Proliferation and Metastasis by Targeting Hippo/YAP Signalling in Colorectal Cancer 

  89. In Vitro and in Vivo Antitumor Effects of Folate-Targeted Ursolic Acid Stealth Liposome 

  90. Sulforaphane induces p53‑deficient SW480 cell apoptosis via the ROS‑MAPK signaling pathway 

  91. Anti-tumor compound RY10-4 suppresses multidrug resistance in MCF-7/ADR cells by inhibiting PI3K/Akt/NF-κB signaling 

  92. TGF-β receptor inhibitor LY2109761 enhances the radiosensitivity of gastric cancer by inactivating the TGF-β/SMAD4 signaling pathway 

  93. Exosome-mediated miR-4655–3p contributes to UV radiation-induced bystander effects 

  94. Resveratrol controlled the fate of porcine pancreatic stem cells through the Wnt/β-catenin signaling pathway mediated by Sirt1 

  95. Nestin protects mouse podocytes against high glucose-induced apoptosis by a Cdk5-dependent mechanism 

  96. Near-infrared photothermal liposomal nanoantagonists for amplified cancer photodynamic therapy 

  97. Inhibition of Autophagy by Deguelin Sensitizes Pancreatic Cancer Cells to Doxorubicin 

  98. p,p′-DDE Induces Apoptosis through the Modulation of Tumor Necrosis Factor α in PC12 Cells 

  99. Oxymatrine induces apoptosis and inhibits invasion in Gallbladder carcinoma via PTEN/PI3K/AKT pathway 

  100. [Gly14]-Humanin Prevents Lipid Deposition and Endothelial Cell Apoptosis in a Lectin-like Oxidized Low-density Lipoprotein Receptor-1-Dependent Manner 

  101. Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway 

  102. Low deacetylation degree chitosan oligosaccharide protects against IL-1β induced inflammation and enhances autophagy activity in human chondrocytes 

  103. Butein attenuates the cytotoxic effects of LPS-stimulated microglia on the SH-SY5Y neuronal cell line 

  104. Berberine inhibits the proliferation of human nasopharyngeal carcinoma cells via an Epstein-Barr virus nuclear antigen 1-dependent mechanism 

  105. CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis 

  106. Insufficient microwave ablation-induced promotion of distant metastasis is suppressed by β-catenin pathway inhibition in breast cancer 

  107. MicroRNA-340-5p modulates cisplatin resistance by targeting LPAATβ in osteosarcoma 

  108. Matrine inhibits cell proliferation and induces apoptosis of human rhabdomyosarcoma cells via downregulation of the extracellular signal‑regulated kinase pathway 

  109. Mst1 overexpression inhibited the growth of human non-small cell lung cancer in vitro and in vivo 

  110. Effect of Mst1 overexpression on the growth of human hepatocellular carcinoma HepG2 cells and the sensitivity to cisplatin in vitro 

  111. MicroRNA-152-5p inhibits proliferation and migration and promotes apoptosis by regulating expression of Smad3 in human keloid fibroblasts 

  112. Iso-suillin from the mushroom Suillus flavus induces cell cycle arrest and apoptosis in K562 cell line 

  113. Different concentrations of 17β-estradiol modulates apoptosis induced by interleukin-1β in rat annulus fibrosus cells 

  114. A series of photosensitizers with incremental positive electric charges for photodynamic antitumor therapy 

  115. Anticancer effect of icaritin on human lung cancer cells through inducing s phase cell cycle arrest and apoptosis 

  116. Identification of m6A-Related lncRNA to Predict the Prognosis of Patients with Hepatocellular Carcinoma 

  117. Chinese herbal formula QHF inhibits hepatocellular carcinoma metastasis via HGF/c-Met signaling pathway 

  118. Development of an Aerobic Glycolysis Index for Predicting the Sorafenib Sensitivity and Prognosis of Hepatocellular Carcinoma 

  119. Low concentrations of bilirubin inhibit activation of hepatic stellate cells in vitro 

  120. Roles of differential expression of miR-543-5p in GH regulation in rat anterior pituitary cells and GH3 cells 

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