Annexin V-APC/PI Apoptosis Kit (贴壁细胞专用)
¥1,010.00 – ¥2,090.00
在售SKU:70-AT107-100, 70-AT107-60, 70-AT107-30, 凋亡, 细胞凋亡, 凋亡试剂盒, 细胞凋亡试剂盒, 凋亡检测, 细胞凋亡检测, 凋亡检测试剂盒, 细胞凋亡检测试剂盒, Annexin V, Annexin, Apoptosis, 贴壁, 贴壁细胞
描述
产品简介
Annexin V(或 Annexin A5)为胞内蛋白膜联蛋白家族成员,以钙依赖的方式与磷脂酰丝氨酸(PS)结合。PS存在于正常细胞浆膜的内层,但在凋亡早期,膜不对称性丧失,PS 易位至细胞表面。荧光标记的 Annexin V可与之特异性结合,表明该细胞为凋亡细胞。
PI(碘化丙啶)是一种核酸染料,它不能透过正常细胞或早期凋亡细胞的完整的细胞膜,但可以透过凋亡晚期和坏死细胞的细胞膜而使细胞核染红。因此,将 Annexin V 与 PI 联合使用时,PI 则被排除在活细胞(Annexin V-/PI-)和早期凋亡细胞(Annexin V+/PI-)之外,而晚期凋亡细胞和坏死细胞同时被荧光标记的Annexin V 和 PI 结合染色呈现双阳性(Annexin V+/PI+)。
Accutase 是一种天然的酶,兼具蛋白水解酶和胶原酶的活性。但它比胰酶和胶原酶更有效,使用浓度更低,使之毒性更小、更温和。因此对细胞的损伤更小,可减少因消化处理带来的假阳性。即便长时间消化,也可保持 90%以上的细胞活力。适合于各种贴壁细胞、胚胎和神经元干细胞等较敏感的细胞的消化。
本试剂盒仅需 15 分钟即可染色样本,快速方便。提供阳性质控液,便于制备单染管,调节补偿。提供消化细胞更温和的 Accutase,减少假阳性。即便长时间消化,也可保持 90%以上的细胞活力。适合于各种贴壁细胞、胚胎和神经元干细胞等较敏感的细胞的消化。本试剂盒仅需 15 分钟即可染色样本,快速方便。提供阳性质控液,便于制备单染管,调节补偿。提供消化细胞更温和的 Accutase,减少假阳性。
产品特点
- 操作简便,15分钟即可完成染色;
- 分群清晰,结果稳定可靠;
- 独家搭配阳性质控液,补偿调节不再困难;
- 提供Accutase Enzyme,适用于贴壁细胞。
结果示例
试剂盒组分
引用文献统计
该产品被引用的文献总数为:71
- Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway
影响因子:5.811刊物:Frontiers in Pharmacology发表日期:2021/5/13 - LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development
影响因子:5.442刊物:CANCER IMMUNOLOGY IMMUNOTHERAPY发表日期:2020/2/15 - Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer
影响因子:5.31刊物:JOURNAL OF CELLULAR AND MOLECULAR MEDICINE发表日期:2021/8/10 - Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes
影响因子:8.554刊物:Clinical and Translational Medicine发表日期:2022/12/19 - Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin‑angiotensin system
影响因子:1.785刊物:Experimental and Therapeutic Medicine发表日期:2020/5/15 - Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process
影响因子:8.469刊物:Cell Death & Disease发表日期:2021/10/20 - STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873
影响因子:5.646刊物:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH发表日期:2019/11/6 - Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells
影响因子:6.78刊物:LIFE SCIENCES发表日期:2022/1/8 - Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation
影响因子:5.307刊物:BIOORGANIC CHEMISTRY发表日期:2022/7/29 - Knockdown of DUXAP10 inhibits proliferation and promotes apoptosis in bladder cancer cells via PI3K/Akt/mTOR signaling pathway
影响因子:3.079刊物:INTERNATIONAL JOURNAL OF ONCOLOGY发表日期:2017/11/7 - The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism
影响因子:6.575刊物:Cancers发表日期:2022/11/25 - TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway
影响因子:5.988刊物:Frontiers in Pharmacology发表日期:2022/12/15 - Hyperhomocysteinemia exacerbates acute kidney injury via increased mitochondrial damage
影响因子:4.755刊物:Frontiers in Physiology发表日期:2022/10/5 - The direct miR-874-3p-target FAM84A promotes tumor development in papillary thyroid cancer
影响因子:6.603刊物:Molecular Oncology发表日期:2021/3/9 - CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
影响因子:1.851刊物:Molecular Medicine Reports发表日期:2019/12/17 - Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway
影响因子:4.236刊物:Frontiers in Microbiology发表日期:2020/12/17 - Long noncoding RNA FAM225A promotes the malignant progression of gastric cancer through the miR-326/PADI2 axis
影响因子:7.109刊物:Cell Death Discovery发表日期:2022/1/11 - Long non-coding RNA CCDC144NL-AS1 sponges miR-143-3p and regulates MAP3K7 by acting as a competing endogenous RNA in gastric cancer
影响因子:6.304刊物:Cell Death & Disease发表日期:2020/7/9 - Circular RNA CDR1as Alleviates Cisplatin-Based Chemoresistance by Suppressing MiR-1299 in Ovarian Cancer
影响因子:4.772刊物:Frontiers in Genetics发表日期:2022/1/26 - Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis
影响因子:3.018刊物:INTERNATIONAL JOURNAL OF ONCOLOGY发表日期:2016/7/15 - Effect of benzo[a]pyrene on proliferation and metastasis of oral squamous cell carcinoma cells: A transcriptome analysis based on RNA-seq
影响因子:4.109刊物:ENVIRONMENTAL TOXICOLOGY发表日期:2022/7/23 - A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells
影响因子:4.599刊物:Frontiers in Genetics发表日期:2021/11/9 - Preliminary mechanism in fetal alloimmune thrombocytopenia associated with anti-HPA 15b antibodies
影响因子:1.697刊物:JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH发表日期:2022/4/6 - LGALS4 as a Prognostic Factor in Urothelial Carcinoma of Bladder Affects Cell Functions
影响因子:1.481刊物:TECHNOLOGY IN CANCER RESEARCH & TREATMENT发表日期:2019/1/1 - Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation
影响因子:3.678刊物:TRANSPLANTATION发表日期:2017/2/1 - Long noncoding RNA FER1L4 promotes the malignant processes of papillary thyroid cancer by targeting the miR-612/ Cadherin 4 axis
影响因子:5.722刊物:Cancer Cell International发表日期:2021/7/21 - Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086
影响因子:4.889刊物:DYES AND PIGMENTS发表日期:2021/3/3 - Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells
影响因子:3.018刊物:INTERNATIONAL JOURNAL OF ONCOLOGY发表日期:2016/10/14 - STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer
影响因子:7.723刊物:OncoImmunology发表日期:2022/3/21 - The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers
影响因子:17.694刊物:Nature Communications发表日期:2022/6/1 - Downregulation of miR-122 attenuates hypoxia/reoxygenation (H/R)-induced myocardial cell apoptosis by upregulating GATA-4
影响因子:2.371刊物:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS发表日期:2016/8/25 - Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts
影响因子:4.145刊物:EXPERIMENTAL CELL RESEARCH发表日期:2022/3/24 - Interferon‑stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response
影响因子:4.136刊物:ONCOLOGY REPORTS发表日期:2022/4/21 - Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer
影响因子:4.322刊物:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY发表日期:2022/7/1 - Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes
影响因子:2.677刊物:Journal of Orthopaedic Surgery and Research发表日期:2022/3/28 - Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response
影响因子:5.714刊物:INTERNATIONAL IMMUNOPHARMACOLOGY发表日期:2022/7/29 - Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis
影响因子:5.241刊物:Cell Death Discovery发表日期:2021/8/25 - NUSAP1 promotes gastric cancer radioresistance by inhibiting ubiquitination of ANXA2 and is suppressed by miR-129-5p
影响因子:2.7刊物:JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY发表日期:2024-08-30 - Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis
影响因子:7.5刊物:Cell Reports发表日期:2024-07-09 - The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma
影响因子:3刊物:MOLECULAR CARCINOGENESIS发表日期:2024-06-05 - Detoxification of DON-induced hepatotoxicity in mice by cold atmospheric plasma
影响因子:6.2刊物:ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY发表日期:2024-06-05 - BET Inhibitor JQ1 Selectively Reduce Tregs by Upregulating STAT3 and Suppressing PD-1 Expression in Patients with Multiple Myeloma
影响因子:3.2刊物:Advanced Biology发表日期:2024-05-26 - P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway
影响因子:16.7刊物:Military Medical Research发表日期:2024-05-20 - ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway
影响因子:3.5刊物:MOLECULAR AND CELLULAR BIOCHEMISTRY发表日期:2024-05-12 - Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway
影响因子:2.8刊物:Discover Oncology发表日期:2024-05-11 - Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21
影响因子:5.3刊物:Cancer Cell International发表日期:2024-05-07 - Vaporization phosphorization-mediated synthesis of phosphorus-doped TiO2 nanocomposites for combined photodynamic and photothermal therapy of renal cell carcinoma
影响因子:6.1刊物:Journal of Materials Chemistry B发表日期:2024-04-09 - PD-1 downregulation enhances CAR-T cell antitumor efficiency by preserving a cell memory phenotype and reducing exhaustion
影响因子:10.3刊物:Journal for ImmunoTherapy of Cancer发表日期:2024-04-01 - Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma
影响因子:3.5刊物:EXPERIMENTAL DERMATOLOGY发表日期:2024-03-21 - WDR4 promotes HCC pathogenesis through N7-methylguanosine by regulating and interacting with METTL1
影响因子:4.4刊物:CELLULAR SIGNALLING发表日期:2024-03-16 - C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription
影响因子:11.4刊物:JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH发表日期:2024-03-13 - Identification of COQ2 as a regulator of proliferation and lipid peroxidation through genome-scale CRISPR-Cas9 screening in myeloma cells
影响因子:5.1刊物:BRITISH JOURNAL OF HAEMATOLOGY发表日期:2024-03-10 - The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway
影响因子:5.3刊物:Chinese Medicine发表日期:2024-02-28 - Closed-loop of Catalyzed Lactate Oxidization Synergistically Sensitizes Apoptosis and Ferroptosis for Cancer Therapy
影响因子:2.6刊物:ChemNanoMat发表日期:2024-02-01 - Comparison of the ability of exosomes and ectosomes derived from adipose-derived stromal cells to promote cartilage regeneration in a rat osteochondral defect model
影响因子:7.1刊物:Stem Cell Research & Therapy发表日期:2024-01-17 - Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway
影响因子:3.1刊物:ONCOLOGY RESEARCH发表日期:2023-12-28 - Synergistic anti-oxidant and anti-inflammatory effects of ceria/resatorvid co-decorated nanoparticles for acute lung injury therapy
影响因子:10.2刊物:JOURNAL OF NANOBIOTECHNOLOGY发表日期:2023-12-21 - Single-cell sequencing analysis related to sphingolipid metabolism guides immunotherapy and prognosis of skin cutaneous melanoma
影响因子:7.3刊物:Frontiers in Immunology发表日期:2023-11-23 - Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer
影响因子:5.2刊物:Frontiers in Endocrinology发表日期:2023-09-25 - Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer
影响因子:8.2刊物:Materials Today Bio发表日期:2023-09-25 - CXXC finger protein 1 (CFP1) bridges the reshaping of genomic H3K4me3 signature to the advancement of lung adenocarcinoma
影响因子:39.3刊物:Signal Transduction and Targeted Therapy发表日期:2023-09-21 - Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling
影响因子:14.5刊物:Acta Pharmaceutica Sinica B发表日期:2023-09-09 - m7G-related genes predict prognosis and affect the immune microenvironment and drug sensitivity in osteosarcoma
影响因子:5.6刊物:Frontiers in Pharmacology发表日期:2023-08-16 - Long non-coding RNA PANDAR promoted radiation and cisplatin-induced DNA damage repair through ATR/CHK1 in NSCLC
影响因子:3.5刊物:JOURNAL OF GENE MEDICINE发表日期:2023-07-17 - NKD1 targeting PCM1 regulates the therapeutic effects of homoharringtonine on colorectal cancer
影响因子:2.8刊物:MOLECULAR BIOLOGY REPORTS发表日期:2023-06-20 - FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity
影响因子:3.1刊物:BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS发表日期:2023-06-14 - Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis
影响因子:10.9刊物:Experimental Hematology & Oncology发表日期:2023-05-17 - Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair
影响因子:15.1刊物:CHEMICAL ENGINEERING JOURNAL发表日期:2023-04-10 - Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 in vivo
影响因子:4.5刊物:JOURNAL OF DRUG TARGETING发表日期:2023-03-03 - Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation
影响因子:5刊物:EUROPEAN JOURNAL OF PHARMACOLOGY发表日期:2023-02-22 - Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis
影响因子:7.4刊物:Journal of Translational Medicine发表日期:2023-02-11
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引用文献
文章目录[隐藏]
- Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway 
- LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development 
- Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer 
- Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes 
- Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin‑angiotensin system 
- Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process 
- STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873 
- Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells 
- Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation 
- Knockdown of DUXAP10 inhibits proliferation and promotes apoptosis in bladder cancer cells via PI3K/Akt/mTOR signaling pathway 
- The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism 
- TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway 
- Hyperhomocysteinemia exacerbates acute kidney injury via increased mitochondrial damage 
- The direct miR-874-3p-target FAM84A promotes tumor development in papillary thyroid cancer 
- CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway 
- Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway 
- Long noncoding RNA FAM225A promotes the malignant progression of gastric cancer through the miR-326/PADI2 axis 
- Long non-coding RNA CCDC144NL-AS1 sponges miR-143-3p and regulates MAP3K7 by acting as a competing endogenous RNA in gastric cancer 
- Circular RNA CDR1as Alleviates Cisplatin-Based Chemoresistance by Suppressing MiR-1299 in Ovarian Cancer 
- Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis 
- Effect of benzo[a]pyrene on proliferation and metastasis of oral squamous cell carcinoma cells: A transcriptome analysis based on RNA-seq 
- A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells 
- Preliminary mechanism in fetal alloimmune thrombocytopenia associated with anti-HPA 15b antibodies 
- LGALS4 as a Prognostic Factor in Urothelial Carcinoma of Bladder Affects Cell Functions 
- Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation 
- Long noncoding RNA FER1L4 promotes the malignant processes of papillary thyroid cancer by targeting the miR-612/ Cadherin 4 axis 
- Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086 
- Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells 
- STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer 
- The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers 
- Downregulation of miR-122 attenuates hypoxia/reoxygenation (H/R)-induced myocardial cell apoptosis by upregulating GATA-4 
- Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts 
- Interferon‑stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response 
- Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer 
- Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes 
- Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response 
- Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis 
- NUSAP1 promotes gastric cancer radioresistance by inhibiting ubiquitination of ANXA2 and is suppressed by miR-129-5p 
- Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis 
- The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma 
- Detoxification of DON-induced hepatotoxicity in mice by cold atmospheric plasma 
- BET Inhibitor JQ1 Selectively Reduce Tregs by Upregulating STAT3 and Suppressing PD-1 Expression in Patients with Multiple Myeloma 
- P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway 
- ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway 
- Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway 
- Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21 
- Vaporization phosphorization-mediated synthesis of phosphorus-doped TiO2 nanocomposites for combined photodynamic and photothermal therapy of renal cell carcinoma 
- PD-1 downregulation enhances CAR-T cell antitumor efficiency by preserving a cell memory phenotype and reducing exhaustion 
- Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma 
- WDR4 promotes HCC pathogenesis through N7-methylguanosine by regulating and interacting with METTL1 
- C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription 
- Identification of COQ2 as a regulator of proliferation and lipid peroxidation through genome-scale CRISPR-Cas9 screening in myeloma cells 
- The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway 
- Closed-loop of Catalyzed Lactate Oxidization Synergistically Sensitizes Apoptosis and Ferroptosis for Cancer Therapy 
- Comparison of the ability of exosomes and ectosomes derived from adipose-derived stromal cells to promote cartilage regeneration in a rat osteochondral defect model 
- Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway 
- Synergistic anti-oxidant and anti-inflammatory effects of ceria/resatorvid co-decorated nanoparticles for acute lung injury therapy 
- Single-cell sequencing analysis related to sphingolipid metabolism guides immunotherapy and prognosis of skin cutaneous melanoma 
- Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer 
- Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer 
- CXXC finger protein 1 (CFP1) bridges the reshaping of genomic H3K4me3 signature to the advancement of lung adenocarcinoma 
- Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling 
- m7G-related genes predict prognosis and affect the immune microenvironment and drug sensitivity in osteosarcoma 
- Long non-coding RNA PANDAR promoted radiation and cisplatin-induced DNA damage repair through ATR/CHK1 in NSCLC 
- NKD1 targeting PCM1 regulates the therapeutic effects of homoharringtonine on colorectal cancer 
- FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity 
- Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis 
- Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair 
- Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 in vivo 
- Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation 
- Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis 
Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway 
LincRNA-p21 knockdown reversed tumor-associated macrophages function by promoting MDM2 to antagonize* p53 activation and alleviate breast cancer development 
Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancer 
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes 
Calcilytic NPS2143 promotes proliferation and inhibits apoptosis of spontaneously hypertensive rat vascular smooth muscle cells via activation of the renin‑angiotensin system 
Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process 
STRA6 exerts oncogenic role in gastric tumorigenesis by acting as a crucial target of miR-873 
Preclinical efficacy and involvement of mTOR signaling in the mechanism of Orf virus against nasopharyngeal carcinoma cells 
Novel isatin-based hybrids as potential anti-rheumatoid arthritis drug candidates: Synthesis and biological evaluation 
Knockdown of DUXAP10 inhibits proliferation and promotes apoptosis in bladder cancer cells via PI3K/Akt/mTOR signaling pathway 
The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism 
TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway 
Hyperhomocysteinemia exacerbates acute kidney injury via increased mitochondrial damage 
The direct miR-874-3p-target FAM84A promotes tumor development in papillary thyroid cancer 
CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway 
Chlamydia trachomatis Plasmid Protein pORF5 Up-Regulates ZFAS1 to Promote Host Cell Survival via MAPK/p38 Pathway 
Long noncoding RNA FAM225A promotes the malignant progression of gastric cancer through the miR-326/PADI2 axis 
Long non-coding RNA CCDC144NL-AS1 sponges miR-143-3p and regulates MAP3K7 by acting as a competing endogenous RNA in gastric cancer 
Circular RNA CDR1as Alleviates Cisplatin-Based Chemoresistance by Suppressing MiR-1299 in Ovarian Cancer 
Metabotropic glutamate receptor 3 is involved in B-cell-related tumor apoptosis 
Effect of benzo[a]pyrene on proliferation and metastasis of oral squamous cell carcinoma cells: A transcriptome analysis based on RNA-seq 
A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells 
Preliminary mechanism in fetal alloimmune thrombocytopenia associated with anti-HPA 15b antibodies 
LGALS4 as a Prognostic Factor in Urothelial Carcinoma of Bladder Affects Cell Functions 
Short-term Pharmacological Inhibition of MyD88 Homodimerization by a Novel Inhibitor Promotes Robust Allograft Tolerance in Mouse Cardiac and Skin Transplantation 
Long noncoding RNA FER1L4 promotes the malignant processes of papillary thyroid cancer by targeting the miR-612/ Cadherin 4 axis 
Albumin-based nanoparticles combined with photodynamic therapy enhance the antitumor activity of curcumin derivative C086 
Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells 
STING agonist cGAMP enhances anti-tumor activity of CAR-NK cells against pancreatic cancer 
The genomic landscape of cholangiocarcinoma reveals the disruption of post-transcriptional modifiers 
Downregulation of miR-122 attenuates hypoxia/reoxygenation (H/R)-induced myocardial cell apoptosis by upregulating GATA-4 
Metformin alleviates dexamethasone-induced apoptosis by regulating autophagy via AMPK/mTOR/p70S6K in osteoblasts 
Interferon‑stimulated gene 15 promotes progression of endometrial carcinoma and weakens antitumor immune response 
Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer 
Cyclic mechanical strain with high-tensile triggers autophagy in growth plate chondrocytes 
Secoisolariciresinol diglucoside-derived metabolite, enterolactone, attenuates atopic dermatitis by suppressing Th2 immune response 
Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis 
NUSAP1 promotes gastric cancer radioresistance by inhibiting ubiquitination of ANXA2 and is suppressed by miR-129-5p 
Extracellular vesicles from alveolar macrophages harboring phagocytosed methicillin-resistant Staphylococcus aureus induce necroptosis 
The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma 
Detoxification of DON-induced hepatotoxicity in mice by cold atmospheric plasma 
BET Inhibitor JQ1 Selectively Reduce Tregs by Upregulating STAT3 and Suppressing PD-1 Expression in Patients with Multiple Myeloma 
P. gingivalis in oral-prostate axis exacerbates benign prostatic hyperplasia via IL-6/IL-6R pathway 
ATP6V1B1 regulates ovarian cancer progression and cisplatin sensitivity through the mTOR/autophagy pathway 
Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway 
Polymorphism rs2327430 in TCF21 predicts the risk and prognosis of gastric cancer by affecting the binding between TFAP2A and TCF21 
Vaporization phosphorization-mediated synthesis of phosphorus-doped TiO2 nanocomposites for combined photodynamic and photothermal therapy of renal cell carcinoma 
PD-1 downregulation enhances CAR-T cell antitumor efficiency by preserving a cell memory phenotype and reducing exhaustion 
Fucoidan suppresses proliferation and epithelial-mesenchymal transition process via Wnt/β-catenin signalling in hemangioma 
WDR4 promotes HCC pathogenesis through N7-methylguanosine by regulating and interacting with METTL1 
C/EBPα-p30 confers AML cell susceptibility to the terminal unfolded protein response and resistance to Venetoclax by activating DDIT3 transcription 
Identification of COQ2 as a regulator of proliferation and lipid peroxidation through genome-scale CRISPR-Cas9 screening in myeloma cells 
The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway 
Closed-loop of Catalyzed Lactate Oxidization Synergistically Sensitizes Apoptosis and Ferroptosis for Cancer Therapy 
Comparison of the ability of exosomes and ectosomes derived from adipose-derived stromal cells to promote cartilage regeneration in a rat osteochondral defect model 
Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway 
Synergistic anti-oxidant and anti-inflammatory effects of ceria/resatorvid co-decorated nanoparticles for acute lung injury therapy 
Single-cell sequencing analysis related to sphingolipid metabolism guides immunotherapy and prognosis of skin cutaneous melanoma 
Crosstalk of RNA methylation writers defines tumor microenvironment and alisertib resistance in breast cancer 
Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer 
CXXC finger protein 1 (CFP1) bridges the reshaping of genomic H3K4me3 signature to the advancement of lung adenocarcinoma 
Identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling 
m7G-related genes predict prognosis and affect the immune microenvironment and drug sensitivity in osteosarcoma 
Long non-coding RNA PANDAR promoted radiation and cisplatin-induced DNA damage repair through ATR/CHK1 in NSCLC 
NKD1 targeting PCM1 regulates the therapeutic effects of homoharringtonine on colorectal cancer 
FUNDC1 modulates mitochondrial defects and pancreatic β-cell dysfunction under lipotoxicity 
Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis 
Cartilage-targeting mRNA-lipid nanoparticles rescue perifocal apoptotic chondrocytes for integrative cartilage repair 
Albumin-encapsulated HSP90-PROTAC BP3 nanoparticles not only retain protein degradation ability but also enhance the antitumour activity of BP3 in vivo 
Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation 
Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis 
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