AT105

Annexin V-APC/7-AAD Apoptosis Kit（细胞凋亡试剂盒 - 贴壁细胞专用）

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¥1,010.00 – ¥2,090.00

在售SKU:70-AT105-30, 70-AT105-60, 70-AT105-100, 凋亡, 细胞凋亡, 凋亡试剂盒, 细胞凋亡试剂盒, 凋亡检测, 细胞凋亡检测, 凋亡检测试剂盒, 细胞凋亡检测试剂盒, Annexin V, Annexin, Apoptosis, 贴壁, 贴壁细胞, 贴壁细胞专用

描述

文章目录[隐藏]

产品简介

Annexin V(或 Annexin A5)为胞内蛋白膜联蛋白家族成员，以钙依赖的方式与磷脂酰丝氨酸(PS)结合。PS 存在于正常细胞浆膜的内层，但在凋亡早期，膜不对称性丧失，PS易位至细胞表面。荧光标记的 Annexin V 可与之特异性结合，表明该细胞为凋亡细胞。

Accutase是一种天然的酶，兼具蛋白水解酶和胶原酶的活性。但它比胰酶和胶原酶更有效，使用浓度更低，使之毒性更小、更温和。因此对细胞的损伤更小，可减少因消化处理带来的假阳性。即便长时间消化，也可保持90%以上的细胞活力。适合于各种贴壁细胞、胚胎和神经元干细胞等较敏感的细胞的消化。

产品特点

  • 操作简便，15分钟即可完成染色；
  • 分群清晰，结果稳定可靠；
  • 独家搭配阳性质控液，补偿调节不再困难；
  • 提供Accutase Enzyme，适用于贴壁细胞。

结果示例

试剂盒组分

引用文献

文章目录[隐藏]


  1. Fucoidan inhibits EGFR redistribution and potentiates sorafenib to overcome sorafenib-resistant hepatocellular carcinoma 

  2. High expression of G-protein signaling modulator 2 in hepatocellular carcinoma facilitates tumor growth and metastasis by activating the PI3K/AKT signaling pathway 

  3. Xylopins A–F, six rare guaiane dimers with three different connecting modes from Xylopia vielana 

  4. Vieloplains A-G, seven new guaiane-type sesquiterpenoid dimers from Xylopia vielana 

  5. S100A16 suppresses the growth and survival of leukaemia cells and correlates with relapse and relapse free survival in adults with Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia 

  6. miR-363-3p inhibits tumor growth by targeting PCNA in lung adenocarcinoma 

  7. Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma 

  8. CAMKIIγ is a targetable driver of multiple myeloma through CaMKIIγ/ Stat3 axis 

  9. PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles 

  10. Long non-coding RNA00844 inhibits MAPK signaling to suppress the progression of hepatocellular carcinoma by targeting AZGP1 

  11. The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway 

  12. PARK2 Suppresses Proliferation and Tumorigenicity in Non-small Cell Lung Cancer 

  13. Identification and Verification of a Novel MAGI2-AS3/miRNA-374-5p/FOXO1 Network Associated with HBV-Related HCC 

  14. Repair of the Urethral Mucosa Defect Model Using Adipose-Derived Stem Cell Sheets and Monitoring the Fate of Indocyanine Green-Labeled Sheets by Near Infrared-II 

  15. SARS-CoV-2 ORF3a inhibits cGAS-STING-mediated autophagy flux and antiviral function 

  16. UHRF1 plays an oncogenic role in small cell lung cancer 

  17. GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair 

  18. TGF-β/Smad Signalling Activation by HTRA1 Regulates the Function of Human Lens Epithelial Cells and Its Mechanism in Posterior Subcapsular Congenital Cataract 

  19. Acetyl-CoA carboxylase 1 depletion suppresses de novo fatty acid synthesis and mitochondrial β-oxidation in castration-resistant prostate cancer cells 

  20. Nrf2 Inhibits the Progression of Parkinson’s Disease by Upregulating AABR07032261.5 to Repress Pyroptosis 

  21. MiR-155-5p suppresses SOX1 to promote proliferation of cholangiocarcinoma via RAF/MEK/ERK pathway 

  22. Leucine zipper downregulated in cancer 1 may serve as a favorable prognostic biomarker by influencing proliferation, colony formation, cell cycle, apoptosis, and migration ability in hepatocellular carcinoma 

  23. Hydroxychloroquine repairs burn damage through the Wnt/β-catenin pathway 

  24. MiR-1976 knockdown promotes epithelial–mesenchymal transition and cancer stem cell properties inducing triple-negative breast cancer metastasis 

  25. Overexpressed Hsp70 alleviated formaldehyde-induced apoptosis partly via PI3K/Akt signaling pathway in human bronchial epithelial cells 

  26. Pomelo polysaccharide extract inhibits oxidative stress, inflammation, and mitochondrial apoptosis of Epinephelus coioides 

  27. ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8+ T cells 

  28. Combined overexpression of four transcription factors promotes effector T cell dedifferentiation toward early phenotypes 

  29. Overexpression of early T cell differentiation-specific transcription factors transforms the terminally differentiated effector T cells into less differentiated state 

  30. HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway 

  31. The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway 

  32. Curcumin Has Anti-Proliferative and Pro-Apoptotic Effects on Tongue Cancer in vitro: A Study with Bioinformatics Analysis and in vitro Experiments 

  33. BI6727, a polo-like kinase 1 inhibitor with promising efficacy on Burkitt lymphoma cells 

  34. Overexpressed MPS-1 contributes to endometrioma development through the NF-κB signaling pathway 

  35. Reduced apurinic/apyrimidinic endonuclease activity enhances the antitumor activity of oxymatrine in lung cancer cells 

  36. Downregulation of ZMYND11 induced by miR-196a-5p promotes the progression and growth of GBM 

  37. Casein kinase 1α inhibits p53 downstream of MDM2‑mediated autophagy and apoptosis in acute myeloid leukemia 

  38. Blocking Triggering Receptor Expressed on Myeloid Cells-1-Positive Tumor-Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti-Programmed Cell Death Ligand 1 Resistance in Liver Cancer 

  39. ANXA1 (Annexin A1) regulated by MYC (MYC proto-oncogene) promotes the growth of papillary thyroid carcinoma 

  40. Kidney Toxicity and Response of Selenium Containing Protein-glutathione Peroxidase (Gpx3) to CdTe QDs on Different Levels 

  41. Dysregulated lncRNA-UCA1 contributes to the progression of gastric cancer through regulation of the PI3K-Akt-mTOR signaling pathway 

  42. A IFI27 gene contributes to ER-stress mediated apoptosis and benefits for white spot syndrome virus infection in Litopenaeus vannamei 

  43. Interleukin-20 differentially regulates bone mesenchymal stem cell activities in RANKL-induced osteoclastogenesis through the OPG/RANKL/RANK axis and the NF-κB, MAPK and AKT signalling pathways 

  44. Berberine-photodynamic therapy sensitizes melanoma cells to cisplatin-induced apoptosis through ROS-mediated P38 MAPK pathways 

  45. Upregulation of CD44v6 contributes to acquired chemoresistance via the modulation of autophagy in colon cancer SW480 cells 

  46. α-Tomatine, a novel early-stage autophagy inhibitor, inhibits autophagy to enhance apoptosis via Beclin-1 in Skov3 cells 

  47. Modification of Mcl-1 alternative splicing induces apoptosis and suppresses tumor proliferation in gastric cancer 

  48. c-Myc induced upregulation of long non-coding RNA SNHG16 enhances progression and carcinogenesis in oral squamous cell carcinoma 

  49. GW4064 enhances the chemosensitivity of colorectal cancer to oxaliplatin by inducing pyroptosis 

  50. ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin 

  51. Expression of long non-coding RNA SFTA1P and its function in non-small cell lung cancer 

  52. Polysaccharide extract from pomelo fruitlet ameliorates diet-induced nonalcoholic fatty liver disease in hybrid grouper (Epinephelus lanceolatus♂ × Epinephelus fuscoguttatus♀) 

  53. Nickle(II) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating the ROS/Akt signaling pathway 

  54. Knockdown of Microtubule Associated Serine/threonine Kinase Like Expression Inhibits Gastric Cancer Cell Growth and Induces Apoptosis by Activation of ERK1/2 and Inactivation of NF-κB Signaling 

  55. Mannose ameliorates experimental colitis by protecting intestinal barrier integrity 

  56. SMYD2 Promotes Hepatocellular Carcinoma Progression by Reprogramming Glutamine Metabolism via c-Myc/GLS1 Axis 

  57. Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway 

  58. POU4F3 Acts as a Tumor Suppressor in Lung Adenocarcinoma via the Endoplasmic Reticulum Stress Signaling Pathway 

  59. Cytotoxicity of perfluorodecanoic acid on mouse primary nephrocytes through oxidative stress: Combined analysis at cellular and molecular levels 

  60. LncRNA-uc002mbe.2 Interacting with hnRNPA2B1 Mediates AKT Deactivation and p21 Up-Regulation Induced by Trichostatin in Liver Cancer Cells 

  61. MiR-221/222 Ameliorates Deoxynivalenol-Induced Apoptosis and Proliferation Inhibition in Intestinal Epithelial Cells by Targeting PTEN 

  62. Construction of a tumor microenvironment pH-responsive cleavable PEGylated hyaluronic acid nano-drug delivery system for colorectal cancer treatment 

  63. Insulin-like growth factor binding protein-1 regulates HIF-1α degradation to inhibit apoptosis in hypoxic cardiomyocytes 

  64. Effects of GPR81 silencing combined with cisplatin stimulation on biological function in hypopharyngeal squamous cell carcinoma 

  65. Hyperhomocysteinemia Exacerbates Cisplatin-induced Acute Kidney Injury 

  66. The role of Melatonin receptor MTNR1A in the action of Melatonin on bovine granulosa cells 

  67. GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathway 

  68. Mycn regulates intestinal development through ribosomal biogenesis in a zebrafish model of Feingold syndrome 1 

  69. Co‑inhibition of BMI1 and Mel18 enhances chemosensitivity of esophageal squamous cell carcinoma in vitro and in vivo 

  70. TRPM8 facilitates proliferation and immune evasion of esophageal cancer cells 

  71. Klotho attenuated Doxorubicin-induced cardiomyopathy by alleviating Dynamin-related protein 1 - mediated mitochondrial dysfunction 

  72. Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes 

  73. Silencing circFTO inhibits malignant phenotype through modulating DUSP4 expression in clear cell renal cell carcinoma 

  74. Panax notoginseng saponins reduces the cisplatin-induced acute renal injury by increasing HIF-1α/BNIP3 to inhibit mitochondrial apoptosis pathway 

  75. Exosome-derived circTRPS1 promotes malignant phenotype and CD8+ T cell exhaustion in bladder cancer microenvironments 

  76. New insights into the release mechanism of Cd2+ from CdTe quantum dots within single cells in situ 

  77. Expression levels of the α7 nicotinic acetylcholine receptor in the brains of patients with Alzheimer's disease and their effect on synaptic proteins in SH-SY5Y cells 

  78. ZNRF3 Regulates Collagen-Induced Arthritis Through NF-kB and Wnt Pathways 

  79. 3‑Bromopyruvic acid regulates glucose metabolism by targeting the c‑Myc/TXNIP axis and induces mitochondria‑mediated apoptosis in TNBC cells 

  80. Blockage of Extracellular Signal-Regulated Kinase Exerts an Antitumor Effect via Regulating Energy Metabolism and Enhances the Efficacy of Autophagy Inhibitors by Regulating Transcription Factor EB Nuclear Translocation in Osteosarcoma 

  81. RNA-binding protein RBM6 as a tumor suppressor gene represses the growth and progression in laryngocarcinoma 

  82. β-8-Oxoguanine DNA Glycosylase Overexpression Reduces Oxidative Stress-Induced Mitochondrial Dysfunction and Apoptosis Through the JNK Signaling Pathway in Human Bronchial Epithelial Cells 

  83. Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure 

  84. The antitumor effect of the novel agent MCL/ACT001 in pancreatic ductal adenocarcinoma 

  85. Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma 

  86. Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor-κ B Signaling Pathway 

  87. β-Elemene alleviates cisplatin resistance in oral squamous cell carcinoma cell via inhibiting JAK2/STAT3 pathway in vitro and in vivo 

  88. Effect of Lentivirus-Mediated miR-499a-3p on Human Umbilical Vein Endothelial Cells 

  89. H. pylori CagA activates the NLRP3 inflammasome to promote gastric cancer cell migration and invasion 

  90. Key Genes And Pathways Controlled By E2F1 In Human Castration-Resistant Prostate Cancer Cells 

  91. Long intergenic non-coding RNA 511 correlates with improved prognosis, and hinders osteosarcoma progression both in vitro and in vivo 

  92. miR-4443 promotes radiation resistance of esophageal squamous cell carcinoma via targeting PTPRJ 

  93. The Combination of Icotinib Hydrochloride and Fluzoparib Enhances the Radiosensitivity of Biliary Tract Cancer Cells 

  94. PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway 

  95. IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma 

  96. Calculated identification of mutator-derived lncRNA signatures of genomic instability to predict the clinical outcome of muscle-invasive bladder cancer 

  97. Regulatory coupling between long noncoding RNAs and senescence in irradiated microglia 

  98. Down regulated oncogene KIF2C inhibits growth, invasion, and metastasis of hepatocellular carcinoma through the Ras/MAPK signaling pathway and epithelial-to-mesenchymal transition 

  99. TRAP1 suppresses oral squamous cell carcinoma progression by reducing oxidative phosphorylation metabolism of Cancer-associated fibroblasts 

  100. Aurora kinase A (AURKA) promotes the progression and imatinib resistance of advanced gastrointestinal stromal tumors 

  101. LncRNA MEG3-210 regulates endometrial stromal cells migration, invasion and apoptosis through p38 MAPK and PKA/SERCA2 signalling via interaction with Galectin-1 in endometriosis 

  102. lncRNA NEAT1 Promotes Colorectal Cancer Progression by Increasing Inflammation 

  103. Effects of YAP1 and SFRP2 overexpression on the biological behavior of colorectal cancer cells and their molecular mechanisms 

  104. Downregulation of CD44v6 Enhances Chemosensitivity by Promoting Apoptosis and Inhibiting Autophagy in Colorectal Cancer HT29 Cells 

  105. Overexpression of miR-340 inhibits cell proliferation and induces apoptosis of human bladder cancer via targeting Glut-1 

  106. P57-mediated autophagy promotes the efficacy of EGFR inhibitors in hepatocellular carcinoma 

  107. Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy 

  108. Exosomal miR-552-5p promotes tumorigenesis and disease progression via the PTEN/TOB1 axis in gastric cancer 

  109. STAM Prolongs Clear Cell Renal Cell Carcinoma Patients' Survival via Inhibiting Cell Growth and Invasion 

  110. Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway 

  111. Identification and Validation of ATF3 Serving as a Potential Biomarker and Correlating With Pharmacotherapy Response and Immune Infiltration Characteristics in Rheumatoid Arthritis 

  112. Discovering novel P38α inhibitors for the treatment of prostate cancer through virtual screening methods 

  113. Protective role of (5R)-5-hydroxytriptolide in lipopolysaccharide-induced acute lung injury by suppressing dendritic cell activation 

  114. Hollow polydopamine spheres with removable manganese oxide nanoparticle caps for tumor microenvironment-responsive drug delivery 

  115. DNA addition polymerization with logic operation for controllable self-assembly of three-dimensional nanovehicles and combinatorial cancer therapy 

  116. A dual drug delivery platform based on thermo-responsive polymeric micelle capped mesoporous silica nanoparticles for cancer therapy 

  117. Bioadaptation of implants to In vitro and In vivo oxidative stress pathological conditions via nanotopography-induced FoxO1 signaling pathways to enhance Osteoimmunal regeneration 

  118. SZB120 Exhibits Immunomodulatory Effects by Targeting eIF2α to Suppress Th17 Cell Differentiation 

  119. lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1 

  120. Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis 

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