BioVision β分泌酶活性荧光检测试剂盒

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http://www.liankebio.com/article-information_Newsletter-443.html

作者:联科生物 发布日期:2015-12-18 00:00

BioVision 公司总部位于美国旧金山湾地区,它是全球生命科学公司的领导者。BioVision在开发和研究细胞凋亡,代谢方面具有卓越的影响力。除了细胞凋亡和代谢分析方面的传统领域,BioVision的高品质产品还覆盖细胞增殖,细胞应激,细胞损伤和修复,糖尿病,肥胖和代谢综合症,干细胞生物学,基因调控,信号转导等多个细胞生物学领域。

联科生物作为BioVision在中国的区域一级代理,小编今日为大家推荐BioVision神经生物学相关的试剂盒,更多产品信息和技术服务欢迎垂电咨询!

Alzheimer’s disease (AD) Research Products

阿尔茨海默病(AD)是一种起病隐匿的进行性发展的神经系统退行性疾病。临床上以记忆障碍、失语、失用、失认、视空间技能损害、执行功能障碍以及人格和行为改变等全面性痴呆表现为特征,病因迄今未明。Biovision提供多种与此日益增长的疾病研究相关的检测试剂盒产品。

β分泌酶活性荧光检测试剂盒

Beta-Secretase Activity Fluorometric Assay Kit (Catalog# K360-100;100 assays;-20℃贮存)

? 产品描述:

β淀粉样蛋白是淀粉样前体蛋白经β-分泌酶(β-Secretase)和γ-分泌酶共同作用产生的,其聚集是形成阿尔茨海默病(Alzheimer’s disease,AD),即老年性痴呆病人脑中老年斑的主要原因。实验证实BACE1(β-site APP cleaving enzyme)是体内主要的β-分泌酶,它与同源蛋白BACE2组成新的天冬氨酸蛋白酶家族。关于β-分泌酶的性质和功能、基因剔除实验、底物选择性、晶体结构和抑制剂研究都有了相应的报道,为进一步开发治疗老年性痴呆的药物奠定了基础。

BioVision的β-分泌酶活性分析试剂盒为检测生物样品或纯化样品中的β-分泌酶提供了一种方便的荧光方法。本分析技术使用了β-分泌酶上一段特有的肽段结合两个报告分子EDANS和DABCYL。在未切割的时候,EDANS发射的荧光会被DABCYL上与其相结合的部分所淬灭。β-分泌酶切割肽段使两者分开,EDANS发出荧光。样品中的β-分泌酶活性水平与其发出的荧光强度成正相关。

? 产品特点:

1. 步骤简单,只需要1小时不到即可完成检测;

2. 操作快速并且方便;

3. 该β-Secretase分泌酶荧光分析试剂盒灵敏、稳定,也适用于高通量分析

目录号 产品名称 规格
K615-100 Choline/Acetylcholine Quantification Colorimetric/Fluorometric Kit 100 assays
K764-100 Acetylcholinesterase Activity Colorimetric Assay Kit 100 assays
K360-100 Beta-Secretase Activity Fluorometric Assay Kit 100 assays
K240-100 Calpain Activity Fluorometric Assay Kit 100 assays
K773-100 Catalase Activity Colorimetric/Fluorometric Assay Kit 100 assays
K615-100 Choline/Acetylcholine Quantification Colorimetric/Fluorometric Kit 100 assays
K253-25 DNA Damage Quantification Colorimetric Kit 25 assays
K264-100 Glutathione (GSH/GSSG/Total) Fluorometric Assay Kit 100 assays
K261-100 Glutathione Colorimetric Assay Kit 100 assays
K251-100 Glutathione Fluorometric Assay Kit 100 assays
K762-100 Glutathione Peroxidase Activity Colorimetric Assay Kit 100 assays
K263-100 GST Colorimetric Activity Assay Kit 100 assays
K260-100 GST Fluorometric Activity Assay Kit 100 assays
K332-100 HAT Activity Colorimetric Assay Kit 100 assays
K331-100 HDAC Activity Colorimetric Assay Kit 100 assays
K330-100 HDAC Activity Fluorometric Assay Kit 100 assays
K340-100 HDAC Inhibitor Drug Screening Kit (Fluorometric) 100 assays
K342-25 HDAC1 Immunoprecipitation (IP) & Activity Assay Kit 25 assays
K341-25 HDAC2 Immunoprecipitation (IP) & Activity Assay Kit 25 assays
K343-100 HDAC3 Activity Fluorometric Assay Kit 100 assays
K344-25 HDAC3 Immunoprecipitation (IP) & Activity Assay Kit 25 assays
K363-100 HDAC3 Inhibitor Screening Kit (Fluorometric) 100 assays
K348-100 HDAC8 Activity Fluorometric Assay Kit 100 assays
K368-100 HDAC8 Inhibitor Screening Kit (Fluorometric) 100 assays
K244-100 Human Calpain 1 Inhibitor Screening Kit (Fluorometric) 100 assays
K339-100 InSitu HDAC Activity Fluorometric Assay Kit 100 assays
K796-100 Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit (Fluorometric) 100 assays
K795-100 Monoamine Oxidase Activity (Total MAO/MAO-A/MAO-B) Fluorometric Assay Kit 100 assays
K797-100 Monoamine Oxidase B (MAO-B) Inhibitor Screening Kit (Fluorometric) 100 assays
K822-100 N′-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay Kit 100 assays
K772-100 Peroxidase Activity Colorimetric/Fluorometric Assay Kit 100 assays
K320-250 Senescence Detection Kit 250 assays
K325-100 SIRT1 Inhibitor/Activator Screening Kit (Fluorometric) 100 assays
K322-100 SIRT2 Inhibitor Screening Assay Kit (Fluorometric) 100 assays
K324-100 Sirtuin Activity Assay Kit (Fluorometric) 100 assays
K335-100 Superoxide Dismutase (SOD) Activity Assay Kit 100 assays
K366-100 TACE Inhibitor Screening Assay Kit ( Fluorometric) 100 assays
K763-100 Thioredoxin Reductase Activity Colorimetric Assay Kit 100 assays
K274-100 Total Antioxidant Capacity (TAC) Colorimetric Assay Kit 100 assays
K571-100 Transglutaminase Activity Assay Kit (Colorimetric) 100 assays
K710-100 Xanthine Oxidase Activity Colorimetric/Fluorometric Assay Kit 100 assays
K685-100 Xanthine/Hypoxanthine Colorimetric/Fluorometric Assay Kit 100 assays
K4699-100 Apolipoprotein E4/Pan-ApoE (human) ELISA Kit 100 assays
K4787-100 Beta-NGF (human) ELISA Kit 100 assays
K4711-100 Neuregulin-1/NRG1-beta1 (human) ELISA Kit 100 assays
K4926-100 NQO1 (human intracellular) ELISA Kit 100 assays
K4771-100 RANTES (Mouse) ELISA Kit 100 assays
K4923-100 Sirtuin 1 (human intracellular) ELISA Kit 100 assays
K4924-100 Sirtuin 2 (human intracellular) ELISA Kit 100 assays
K4754-100 TACE (human) ELISA Kit 100 assays