细胞并不只是原生质囊泡,它们含有一些细胞器与结构,每种都有其各自独特的功能。为了详细了解一个细胞器的特征及组成,通常需要先对其进行纯化。此外,表征一种新的蛋白也需要知道它的位置,使用其它一些已经定位清楚的蛋白(标记物)作为对照是一种十分有用的策略。
Novus提供大量细胞器标记物抗体,方便细胞器蛋白及功能的研究。
1.Novus自噬体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Autophagosomes
|
LC3B/MAP1LC3B
|
NB100-2220
|
Rb/Poly
|
SW,IHC-Fr,WB,IHC-P,ELISA,IP ICC/IF,
|
Hu,Bv, Ca,Mu,Ha,
Rt, Pm,Po, Ba,Ze
|
392
|
Autophagosomes
|
LC3B/MAP1LC3B
|
NB600-1384
|
Rb/Poly
|
SW,IHC-Fr,WB,IHC-PEM, Flow, ICC/IF,
|
Hu,Ca, Pm,Mu, Ze
Rt, Po, Bv,
|
132
|
Autophagosomes
|
LC3/MAP1LC3A
|
NB100-2331
|
Rb/Poly
|
SW,IHC-Fr,WB,IHC-P,ELISA,IP Flow, ICC/IF,
|
Hu, Mu, Rt, Ca, Fi,
Ze
|
139
|
2.Novus细胞连结
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Adherens Junctions
|
E-Cadherin
|
NBP2-19051
|
Mu/Mono
|
WB, ELISA, Flow,
ICC/IF, IHC-P |
Hu, Mu, Rt, Pm
|
2
|
Adherens Junctions
|
N-Cadherin
|
NBP1-48309
|
Mu/Mono
|
SW, WB, ICC/IF,
IHC-P, IP
|
Hu, Mu, Rt
|
20
|
Adherens Junctions
|
P-Cadherin
|
NBP1-59222
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu,Eq, RbMu, Rt,
Po, Bv, Ca,
|
1
|
Adherens Junctions
|
VE-Cadherin
|
NB600-1409
|
Mu/Mono
|
WB, Flow, Func,
ICC/IF, IHC-Fr, IP
|
Hu
|
1
|
Gap Junctions
|
Connexin 43
|
NB300-309
|
Rb/Poly
|
WB
|
Rt, Av
|
1
|
Tight Junctions
|
ZO1/TJP1
|
NBP1-85046
|
Rb/Poly
|
ICC/IF, IHC-P
|
Hu
|
2
|
Desmosomes
|
Desmoglein-2
|
NBP1-85709
|
Rb/Poly
|
ICC/IF, IHC-P
|
Hu
|
1
|
3.Novus中心体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Centrosome
|
Pericentrin
|
NB100-61071
|
Rb/Poly
|
ICC/IF, IHC-P, IP
|
Hu
|
3
|
Centrosome
|
gamma Tubulin
|
NB500-574
|
Mu/Mono
|
WB, ICC/IF
|
Hu, Mu, Rt, Po, Bv, Ch, Pl
|
17
|
Centromere
|
CENPA
|
NBP1-64755
|
Rb/Poly
|
ELISA, ICC/IF,
IHC-P
|
Hu
|
-
|
4.Novus细胞骨架
细胞器 |
标记物名称 |
目录号 |
种属来源 |
应用 |
交叉反应性 |
参考文献 |
Actin Filaments |
beta-Actin |
NB100-56874 |
Rb/Poly |
SW, WB, IHC-P |
Hu, Mu, Rt, In |
40 |
Microtubules |
alpha Tubulin |
NB100-690 |
Mu/Mono |
SW,IHC-Fr,WB,IHCP,Flow,IPICC/IF, |
Hu,Ha,Dr,Mu,Fu,Rt,Gp,Po,Pm,Av,Bv,Rb,Ca,Xp,Ch,Ye |
44 |
Microtubules |
beta Tubulin |
NB100-56459 |
Rb/Poly |
SW, WB, IHC-P |
Hu,Mu, Rt, Bv, Ca, Ch,Fe, Pm, Xp |
6 |
Intermediate Filamants |
Cytokeratin |
NBP2-29429 |
Mu/Mono |
WB,IHC-Fr,Flow,IHC-PICC/IF, |
Hu, Mu, Rt, Bv, Ca, Ch, Pm, Rb |
9 |
Intermediate Filamants |
Vimentin |
NB300-223 |
Ch/Poly |
WB, ICC/IF, IHC-Fr, IHC-P |
Hu, Mu, Rt |
12 |
5.Novus内质网
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
ER
|
Calreticulin
|
NB600-101
|
Rb/Poly
|
SW,ICC/IF,WB,IHC-Fr,B/N,IP,DB,PAEM,
|
Hu, Mu, Rt, Bv, Ha, Pm
|
19
|
ER
|
Pdi1p
|
NBP1-05391
|
Mu/Mono
|
WB, ICC/IF
|
Ye
|
-
|
ER
|
PDI
|
NB300-517
|
Mu/Mono
|
WB,IHCFr,B/N,IHC-P,ELISA,IP Flow, ICC/IF,
|
Hu, Mu, Rt, Po, Ha, Pm
|
15
|
ER
|
KDEL
|
NBP1-97469
|
Mu/Mono
|
WB,IHC-P,EM,IP ELISA, Flow, ICC/IF,
|
Hu,In,Ma,Mu,Pl,
Rt,Pm,Av, YeCh,
|
20
|
ER Membrane
|
Calnexin
|
NB100-1965
|
Rb/Poly
|
SW, WB, ICC/IF, IHC-P, IP
|
Hu,Gp,Rb,Mu,Sh,Rt, Xp,Po, ZeAv, Bv, Ch, Dr,
|
5
|
ER Stress
|
GADD153
|
NB600-1335
|
Mu/Mono
|
SW, WB, GS, ICC/IF, IHC-P, IP
|
Hu, Mu, Rt, Pm
|
13
|
ER Stress
|
GRP78
|
NBP1-06274
|
Rb/Poly
|
SW, WB, Flow, ICC/IF
|
Hu, Mu, Rt, Ch, Sh
|
5
|
6.Novus核内体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Early Endosomes
|
EEA1
|
NBP1-30914
|
Rb/Poly
|
WB, DB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
3
|
Early Endosomes
|
EEA1
|
NBP2-36568
|
Mu/Mono
|
WB, IHC-P, Flow-IC
|
Hu, Mu
|
-
|
Early Endosomes
|
EEA1
|
NBP2-36569
|
Mu/Mono
|
WB,IHC-P, Flow-IC
|
Hu, Mu
|
-
|
Early Endosomes
|
Rab5a
|
NBP1-04340
|
Mu/Mono
|
WB, ELISA
|
Hu
|
-
|
Early Endosomes
|
Rab5a
|
NB120-13253
|
Rb/Poly
|
WB, ICC/IF, IHC-P, IP
|
Hu, Mu, Rt,Bv,Pm
|
8
|
Recycling Endosomes
|
TfR (Transferrin R)
|
NB100-64979
|
Rt/Mono
|
Flow, Func, ICC/IF, IHC-Fr, In vivo
|
Mu
|
5
|
Recycling Endosomes
|
TfR (Transferrin R)
|
NB100-92243
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
4
|
Recycling Endosomes
|
Rab11A
|
NB120-3612
|
Rb/Poly
|
WB
|
Hu, Pm
|
-
|
Late Endosomes
|
CD63
|
NB100-77913
|
Mu/Mono
|
WB, Flow, ICC/IF, IHC-P, IP
|
Hu, Mu
|
6
|
Late Endosomes
|
CD63
|
NBP2-42225
|
Mu/Mono
|
WB, DB,EM, ELISA, Flow, Func, ICC/IF, IP
|
Hu
|
10
|
Late Endosomes
|
IGF-II R
|
NB300-514
|
Mu/Mono
|
WB, ELISA, Flow, ICC/IF, IHC-P, IP
|
Hu, Mu, Rt, Bv, Pm
|
6
|
Late Endosomes
|
Rab7a
|
NBP2-24591
|
Rb/Poly
|
WB, IHC-P
|
Hu,Ch, PmMu, Rt, Bv, Ca,
|
-
|
Caveolae, Endosomes
|
Caveolin-1
|
NB100-615
|
Mu/Mono
|
WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP
|
Hu, Mu, Rt, Sh
|
13
|
7.Novus高尔基体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Golgi Apparatus
|
58K Golgi Protein
|
NB600-412
|
Mu/Mono
|
WB,IHC-PICC/IF, IHC-Fr,
|
Hu, Mu, Rt, Bv, Ca, Ch
|
18
|
Golgi Apparatus
|
GOLM1
|
NBP1-50627
|
Rb/Poly
|
WB, ICC/IF
|
Hu
|
-
|
Golgi Apparatus
|
GM130
|
NBP1-89756
|
Rb/Poly
|
ICC/IF, IHC-P
|
Hu
|
1
|
trans-Golgi network
|
TGN38
|
NBP1-03495
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
2
|
trans-Golgi network
|
TGN38
|
NB300-575
|
Mu/Mono
|
WB,IHC-P,B/N,IP Flow, ICC/IF,
|
Hu, Mu, Rt, Ch, Ha, Mk, Rb
|
3
|
trans-Golgi network
|
TGN46
|
NBP1-49643
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu
|
3
|
trans-Golgi network
|
Furin
|
NBP2-24687
|
Rb/Poly
|
IHC-P
|
Hu, Mu, Rt, Bv, Ca, Eq, Pm
|
-
|
8.Novus溶酶体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Lysosomes
|
Cathepsin D
|
NB600-1295
|
Mu/Mono
|
WB, EM, ELISA, ICC/IF, IHC-P, MiAr
|
Hu
|
4
|
Lysosomes
|
LIMPII
|
NB400-129
|
Rb/Poly
|
WB, ICC/IF, IHC-P, IP
|
Hu, Mu, Rt, Ca, Pm
|
7
|
Lysosomes
|
LIMPII
|
NB400-102
|
Rb/Poly
|
WB, Flow, ICC/IF, IHC-P
|
Hu, Mu, Rt,Bv, Ha, Md
|
9
|
Lysosomes
|
LAMP-2/CD107b
|
NBP2-22217
|
Mu/Mono
|
SW, WB, Flow, ICC/IF, IHC-Fr, IHC-P
|
Hu
|
28
|
Lysosomes
|
LAMP-1/CD107a
|
NBP2-25155
|
Mu/Mono
|
WB, ICC/IF
|
Hu, Mu, Rt, Po, Bv
|
-
|
Lysosomes
|
LAMP-2/CD107b
|
NB100-77525
|
Rt/Mono
|
Flow, IHC-Fr, IP
|
Mu
|
7
|
Lysosomes
|
LAMP-1/CD107a
|
NB120-19294
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
12
|
9.Novus线粒体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Mitochondria
|
Cytochrome c
|
NB100-56503
|
Mu/Mono
|
WB, Flow, ICC/IF, IHC-P
|
Hu,Ma,Mu,Rb Po, Ca, Dr, Eq,
|
42
|
Mitochondria
|
Cytochrome c
|
NBP2-24872
|
Mu/Mono
|
B/N, IHC-Fr, IP
|
Hu, Mu, Rt
|
5
|
Mitochondria
|
SDHB
|
NBP1-54154
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu
|
1
|
Mitochondria
|
Mitofilin
|
NB100-1919
|
Rb/Poly
|
WB, ICC/IF, IP, IHC-P
|
Hu, Mu,Rt, Ca,Fe
|
4
|
Mitochondria
|
COX4
|
NB110-39115
|
Rb/Poly
|
SW, WB, ICC/IF, IHC-P
|
Hu, Mu, Rt, Po, Bv, Pm
|
2
|
Mitochondria
|
HSP60
|
NBP1-77396
|
Rb/Poly
|
SW, WB, ICC/IF, IHC-P
|
Hu, Mu, Rt, Ha, Pm
|
-
|
Mitochondrial Matrix
|
MRPL40
|
NBP1-82620
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
-
|
10.Novus细胞核
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Nucleus
|
Histone H2BS
|
NB100-56347
|
Rb/Poly
|
WB, IHC-P
|
Hu, Mu, Rt, Ca, Ch, Dr, Ma, Ze
|
11
|
Nucleus
|
Histone H3
|
NB500-171
|
Rb/Poly
|
WB, ChIP, ICC/IF, IHC-P
|
Hu, Mu, Rt, Xp, Ye
|
5
|
Nucleus
|
Histone H4
|
NB100-56348
|
Rb/Poly
|
WB
|
Hu
|
1
|
Nucleus
|
LSD1
|
NB100-1762
|
Mu/Mono
|
SW, WB, ChIP, ELISA, IHC-P
|
Hu, Mu, Pm
|
8
|
Nucleus
|
MeCP2
|
NB100-56326
|
Rb/Poly
|
WB, ICC/IF
|
Hu
|
1
|
Nucleus
|
ASH2L
|
NB600-250
|
Rb/Poly
|
WB, ChIP, IHC-P, IP, PLA
|
Hu
|
12
|
Nuclear Envelope
|
Lamin B1
|
NB100-56403
|
Rb/Poly
|
WB
|
Hu
|
3
|
Nuclear Envelope
|
Lamin A + C
|
NB100-56649
|
Rb/Poly
|
WB, ICC/IF, Flow-IC
|
Hu
|
4
|
Nucleolus
|
Fibrillarin
|
NB300-269
|
Mu/Mono
|
WB,IHC-P,Flow,IHC-WhMtICC/IF, IHC-Fr,
|
Hu,Dr, Pl,Mu,YeRt, C. elegans, Ch,
|
5
|
Nuclear Speckle
|
SC35
|
NB100-1774
|
Mu/Mono
|
WB, EM, ELISA, ICC/IF, IP
|
Hu, Rt, Am, Dr
|
4
|
Heterochromatin
|
HP1 alpha
|
NBP2-24602
|
Rb/Poly
|
WB
|
Hu, Mu, Ca, Pm
|
-
|
11.Novus过氧化物酶体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Peroxisome
|
Catalase
|
NBP2-24916
|
Rb/Poly
|
WB, IHC-P
|
Hu, Mu, Rt, Bv
|
3
|
Peroxisome
|
ACAA1
|
NBP1-85786
|
Rb/Poly
|
WB, ICC/IF, IHC-P
|
Hu, Mu, Rt
|
-
|
Proxisomal Membrane
|
PMP70
|
NBP1-20871
|
Gt/Poly
|
WB, IHC-P
|
Hu, Rt
|
1
|
12.Novus核糖体
细胞器
|
标记物名称
|
目录号
|
种属来源
|
应用
|
交叉反应性
|
参考文献
|
Ribosomes
|
RPL7A
|
NB100-2277
|
Rb/Poly
|
WB, IHC-P, IP
|
Hu, Mu
|
2
|
Ribosomes
|
RPS6
|
NB100-1595
|
Rb/Poly
|
WB, IP
|
Hu, Mu
|
2
|
Ribosomes
|
RPS3
|
NBP1-33691
|
Rb/Poly
|
WB, ICC/IF, IHC, IHC-P
|
Hu, Mu, Rt
|
-
|
详情请致电授权经销商——杭州联科生物技术股份有限公司
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