Novus神经生物学研究：亨廷顿氏舞蹈症

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作者：Novus官网 发布日期：2014-08-01 11:00

Novus神经生物学研究：亨廷顿氏舞蹈症
亨廷顿氏舞蹈症（Huntington's disease HD）是一种神经退行性疾病，病发时会无法控制四肢，就像手舞足蹈一样。该疾病由美国医学家乔治·亨丁顿于1872年发现，因而得名。该病是由一个变异型亨廷顿基因引起，该基因可具有许多个氨基酸拷贝的蛋白质。正常的亨廷顿蛋白含有10-25段谷氨酰胺序列，但如果有36段以上的谷氨酰胺序列时，该蛋白质的形状即发生改变，并在神经元内形成大的丛群。这将杀灭大脑纹状体部位的这些细胞，从而导致特有的协调力丧失和痴呆症。

Novus提供亨廷顿氏舞蹈症研究相关的产品，为科研用户提供方便

Catalog：NB500-210 Product: Caspase 3 (CPP32 4-1-18) Antibody Species: Hu, Rt, Applications: WB,IHC 相关指标: BDNF Caspase 3 Choline Acetyltransferase GM-CSF HIP1 HOXA13 Huntingtin LAMC2 Somatostatin
Catalog：NB300-204 Product: HIP1 (1B11) Antibody Species: Hu, Mu Applications: WB, IP
Catalog：NBP1-03377 Product: Huntingtin Antibody Species: Mu, Rt Applications: WB, IF, IHC-Fr, IHC-P
Catalog：NBP1-89710 Product: Huntingtin Antibody Species: Hu Applications: IF, IHC-P

产品引用文献

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2.[Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Fuzio P, Ditonno P, Rutigliano M, et al. Regulation of TGF-1 expression by Androgen Deprivation Therapy of prostate cancer. Cancer Letters. 2012 28;318(2):135-144.[PMID: 22269108]

3.[Caspase 3 (CPP32 4-1-18) Antibody NB500-210] Hsu L-C, Hsu Y-W, Liang Y-H, et al. Induction of Apoptosis in Human Breast Adenocarcinoma Cells MCF-7 by Monapurpyridine A, a New Azaphilone Derivative from Monascus purpureus NTU 568. Molecules. 2012 17(1):664-673. [PMID: 22237681]

4.[Choline Acetyltransferase Antibody NBP1-30052] Sciamanna G, Tassone A, Martella G, et al. Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia. PLoS ONE. 2011 6(9). [PMID: 21912682]

5.[Somatostatin Receptor 2 Antibody NB300-157] Li F, Ryu BY, Krueger RL, et al. Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to wild type viral glycoproteins. Journal of Virology. 2011 Oct 19. [PMID: 22013043]???????联科生物代理截止时间：2017年6月30日