外泌体是一种直径为30-100nm的纳米级脂质包裹体结构,内部包裹了蛋白、mRNA和microRNA等物质,包括肿瘤细胞在内的几乎所有类型的细胞,都可以产生并释放外泌体。外泌体由细胞分泌释放出来,在血液等体液内传播,最后又可被其他细胞吞噬,是细胞间通讯的重要介质。
外泌体目前被视为特异性分泌的膜泡,参与细胞间通讯,对外泌体的研究兴趣日益增长,从外泌体研究方向而言,干细胞、免疫、microRNA、靶向给药等都是热门研究领域,2013年诺贝尔生物/医学奖授予三位在细胞囊泡方面贡献突出的科学家,使外泌体的研究达到全新的高度,外泌体将在癌症的诊断及治疗等领域发挥重要作用。
外泌体产生过程的示意图:
Novus提供提供多种试剂、工具和方案用于分离、表征和分析外泌体RNA和蛋白质内含物,部分产品列举如下:
1.外泌体定量试剂盒
产品特点:适用不同样本类型;仅需100ul样本;采用夹心法ELISA技术。
产品原理图:部分产品列表:
目录号 |
产品名称 |
样本类型 |
H6-NBP2-49782 |
Overall Exosome Capture and Quantification |
血浆 |
H6-NBP2-49783 |
Overall Exosome Capture and Quantification |
尿液 |
H6-NBP2-49785 |
Overall Exosome Capture and Quantification |
血清 |
H6-NBP2-49787 |
Overall Exosome Capture and Quantification |
细胞培养物 |
H6-NBP2-49786 |
Tumor-derived Exosome Enrichment & Quantification |
体液、细胞培养物 |
2.外泌体RNA提取试剂盒
产品特点:简单、高效提取外泌体总RNA;提取物适用于下游实验。
产品原理图:部分产品列表:
目录号 |
产品名称 |
样本类型 |
H6-NBP2-49789 |
Exosome RNA Extraction |
纯化的外泌体 |
H6-NBP2-49784 |
Overall Exosome Capture and RNA Extraction |
体液、细胞培养物 |
H6-NBP2-49788 |
Tumor-derived Exosome Capture & RNA Extraction |
体液 |
3.外泌体标准品
产品特点:用于阳性质控;源于多种样本;经多种实验(FCM,WB,ELISA)反复验证。
产品原理图:
部分产品列表:
目录号 |
外泌体来源 |
目录号 |
外泌体来源 |
H6-NBP2-49838 |
Plasma (Human) |
H6-NBP2-49860 |
DAUDI Cells (Human) |
H6-NBP2-49842 |
Saliva (Human) |
H6-NBP2-49854 |
HCT116 Cells (Human) |
H6-NBP2-49827 |
Serum (Human) |
H6-NBP2-49864 |
K562 Cells (Human) |
H6-NBP2-49840 |
Urine (Human) |
H6-NBP2-49847 |
MM1 Cells (Human) |
H6-NBP2-49862 |
A549 Cells (Human) |
H6-NBP2-49856 |
PC3 Cells (Human) |
H6-NBP2-49849 |
BLCL21 Cells (Human) |
H6-NBP2-49852 |
SK-N-SH Cells (Human) |
H6-NBP2-49858 |
BPH-1 Cells (Human) |
H6-NBP2-49844 |
U87-MG Cells (Human) |
H6-NBP2-49845 |
COLO1 Cells (Human) |
H6-NBP2-49866 |
B16F10 Cells (Mouse) |
4.外泌体预吸附板
产品特点:预吸附外泌体相关的捕获抗体;仅需100ul样品;操作简单、即用型。
产品原理图:
部分产品列表:
目录号 |
产品名称 |
检测方法 |
H6-NBP2-49802 |
Overall Exosome Isolation from Biofluids |
Colorimetric |
H6-NBP2-49803 |
Overall Exosome Isolation from Biofluids |
Luminometric |
H6-NBP2-49804 |
Overall Exosome Isolation from Biofluids |
Fluorometric |
H6-NBP2-49805 |
Overall Exosome Isolation from Serum |
Colorimetric |
H6-NBP2-49806 |
Overall Exosome Isolation from Serum |
Luminometric |
H6-NBP2-49807 |
Overall Exosome Isolation from Serum |
Fluorometric |
H6-NBP2-49808 |
Overall Exosome Isolation from Saliva |
Colorimetric |
H6-NBP2-49809 |
Overall Exosome Isolation from Saliva |
Luminometric |
H6-NBP2-49810 |
Overall Exosome Isolation from Saliva |
Fluorimetric |
H6-NBP2-49811 |
Overall Exosome Isolation from Cell Media |
Colorimetric |
H6-NBP2-49812 |
Overall Exosome Isolation from Cell Media |
Luminometric |
H6-NBP2-49813 |
Overall Exosome Isolation from Cell Media |
Fluorimetric |
H6-NBP2-49814 |
Tumor-derived Exosome Isolation from Plasma |
Colorimetric |
H6-NBP2-49815 |
Tumor-derived Exosome Isolation from Plasma |
Luminometric |
H6-NBP2-49816 |
Tumor-derived Exosome Isolation from Plasma |
Fluorimetric |
H6-NBP2-49800 |
Neural-derived Exosome Isolation from Plasma |
Colorimetric |
H6-NBP2-49817 |
Neural-derived Exosome Isolation from Plasma |
Luminometric |
H6-NBP2-49818 |
Neural-derived Exosome Isolation from Plasma |
Fluorimetric |
H6-NBP2-49819 |
Glial-derived Exosome Isolation from Plasma |
Colorimetric |
H6-NBP2-49820 |
Glial-derived Exosome Isolation from Plasma |
Luminometric |
H6-NBP2-49821 |
Glial-derived Exosome Isolation from Plasma |
Fluorimetric |
H6-NBP2-49822 |
Monocytes/Platelet-derived Exosome Isolation from Plasma |
Colorimetric |
H6-NBP2-49823 |
Monocytes/Platelet-derived Exosome Isolation from Plasma |
Luminometric |
H6-NBP2-49824 |
Monocytes/Platelet-derived Exosome Isolation from Plasma |
Fluorimetric |
5.外泌体分离微球
产品特点:富集分离外泌体;分离后便于解离,与下游实验兼容;提供0.4um和1.0um两种大小的微球;使用简单、高效、快速。
产品原理图:部分产品列表:
目录号 |
产品名称 |
样本类型 |
微球大小 |
H6-NBP2-49826 |
Overall Exosome Isolation |
Cell media |
0.4 µm |
H6-NBP2-49828 |
Overall Exosome Isolation |
Cell media |
1.0 µm |
H6-NBP2-49829 |
Tumor-Derived Exosome Isolation |
Biofluids |
0.4 µm |
H6-NBP2-49830 |
Tumor-Derived Exosome Isolation |
Biofluids |
1.0 µm |
H6-NBP2-49835 |
Overall Exosome Isolation |
Biofluids |
0.4 µm |
H6-NBP2-49836 |
Overall Exosome Isolation |
Biofluids |
1.0 µm |
H6-NBP2-49831 |
Overall Exosome Isolation |
Mouse biofluids |
0.4 µm |
H6-NBP2-49832 |
Overall Exosome Isolation |
Mouse biofluids |
1.0 µm |
H6-NBP2-49833 |
Overall Exosome Isolation |
Mouse cell media |
0.4 µm |
6.外泌体标记抗体s
部分产品列表:
目录号 |
标记物 |
来源/类型 |
应用 |
交叉反应性 |
H6-NBP1-90201 |
Alix |
Rb/Poly |
WB, ICC/IF, IHC-P |
Hu, Mu, Rt |
H6-MAB5248 |
CD24 |
Mu/Mono |
IHC-P |
Hu |
H6-NBP2-42225 |
CD63 |
Mu/Mono |
WB, DB, EM, ELISA,more |
Hu |
H6-MAB5417 |
CD63 |
Rt/Mono |
Flow, IHC-Fr |
Mu |
H6-NBP2-36567 |
CD63 |
Rt/Mono |
WB, Flow |
Hu, Mu |
H6-NB100-77913 |
CD63 |
Mu/Mono |
WB, Flow, ICC/IF, more |
Hu |
H6-NB100-65805 |
CD81 |
Mu/Mono |
WB, ELISA, Flow, ICC/IF, more |
Hu, Gt, Pm |
H6-MAB4865 |
CD81 |
Rt/Mono |
Flow, |
Mu |
H6-NBP2-22187 |
CD9 |
Mu/Mono |
WB, ELISA, Flow, IHC-P |
Hu |
H6-MAB5218 |
CD9 |
Rt/Mono |
Flow, IHC-Fr |
Mu |
H6-NB100-77915 |
CD9 |
Mu/Mono |
Flow, ICC/IF |
Hu, Bv, Ca, |
H6-NB200-112 |
TSG101 |
Mu/Mono |
WB, ELISA, Flow,more |
Hu, Mu, Rt, |
H6-NBP1-80659 |
TSG101 |
Rb/Poly |
WB, ICC/IF, IHC-P |
Hu, Mu, Rt |
更多外泌体研究产品,请关注:Nouvs外泌体研究产品???????联科生物代理截止时间:2017年6月30日
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