Novus动脉粥样硬化热销产品简介

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http://www.liankebio.com/article-information_Newsletter-447.html

作者：联科生物 发布日期：2016-07-19 10:00

动脉粥样硬化（atherosclerosis，AS）是冠心病、脑梗死、外周血管病的主要原因。脂质代谢障碍为动脉粥样硬化的病变基础，其特点是受累动脉病变从内膜开始，一般先有脂质和复合糖类积聚、出血及血栓形成，进而纤维组织增生及钙质沉着，并有动脉中层的逐渐蜕变和钙化，导致动脉壁增厚变硬、血管腔狭窄。病变常累及大中肌性动脉，一旦发展到足以阻塞动脉腔，则该动脉所供应的组织或器官将缺血或坏死。由于在动脉内膜积聚的脂质外观呈黄色粥样，因此称为动脉粥样硬化。

Figure A shows a normal artery with normal blood flow. The inset image shows a cross-section of a normal artery. Figure B shows an artery with plaque buildup.
Novus提供动脉粥样硬化研究相关产品，部分热销产品列表如下：

蛋白 目录号 种属/类型 应用 交叉反应性 引用文献
CYBB/NOX2 H6-NBP1-19168 Mu/Mono WB Hu
CYBB/NOX2 H6-NBP1-51928 Gt/Poly WB, ELISA, IF Hu, Mu, Rt
HDL H6-NBP1-76563 Rb/Poly WB, ELISA Hu
NOX4 H6-NB110-58849 Rb/Poly WB,IF,IHC-P Hu,Rt, Bv,more 7
NOX4 H6-NB110-58851 Rb/Poly WB,ICC,ICC, IF Hu,Mu,Rt,Mk 11
SR-BI H6-NB400-101 Rb/Poly WB, FACS, more Mu 64
SR-BI H6-NB400-131 Gt/Poly WB, ICC, IF Hu, Mu, Rt 8
SR-BI H6-NB400-104 Rb/Poly WB,ICC,,more Hu,Mu Rt 70
SR-BI H6-NB400-113 Rb/Poly WB,B/N, ICC,IF,IP Hu, Mu, 8
SR-BI/SR-BII H6-NB400-134 Rb/Poly WB,ICC,IF,IHC,FACS Mu 3
SR-BII H6-NB400-102 Rb/Poly WB, IF, IHC-P Hu, Mu, Rt, Bv 7

产品引用文献
1. [SR-BI Antibody NB400-101] Saha S, Graessler J, Schwarz PE, et al. Modified high-density lipoprotein modulates aldosterone release through scavenger receptors via extra cellular signal-regulated kinase and Janus kinase- dependent pathways. Mol Cell Biochem. 2012 Mar 1. [PMID: 22382638]

2. [SR-BII Antibody NB400-102] Kushiyama A, et al. Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):291-8.[PMID: 22095983]

3. [SR-BI Antibody NB400-104] Molina-Jimenez F, Benedicto I, Dao Thi VL, et al. Matrigel-embedded 3D culture of Huh-7 cells as a hepatocyte-like polarized system to study hepatitis C virus cycle. Virology. 2012 Jan 24.[PMID: 22280897]

4. [SR-BI Antibody NB400-104] Storey SM, McIntosh AL, Huang H, et al. Intracellular Cholesterol Binding Proteins Enhance HDL-mediated Cholesterol Uptake in Cultured Primary Mouse Hepatocytes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 2012 Jan 12. [PMID: 22241858]

5. [SR-BI Antibody NB400-113] Kim K-Y, Stevens MV, Akter MH, et al. Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells. J Clin Invest. 2011 Aug 25. [PMID: 21865652]

6. [SR-BI/SR-BII Antibody NB400-134] Hu J, Zhang Z, Shen W-J, et al. Differential Roles of Cysteine Residues inCellular Trafficking, Dimerization, and Function of the HDL Receptor, SR-BI. Biochemistry. 2011 Nov 18.[PMID: 22097902] 更多产品，敬请关注：Novus官网联科生物代理截止时间：2017年6月30日