KIT 分子靶点信息 - KIT分子别称 | 人/小鼠/大鼠KIT分子靶点功能 | KIT分子靶点检测

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KIT 分子靶点信息概述
KIT 分子靶点综述
KIT, KIT proto-oncogene, receptor tyrosine kinase 分子靶点种属信息
KIT 分子产品列表
Anti-Human CD117, PE(Clone：104D2) (新品)
Anti-Mouse CD117(c-Kit)，PE-Cy7 (Clone: ACK2) 流式抗体 (新品)
Anti-Human CD117, PE-Cy7(Clone：104D2) (新品)
Anti-Mouse CD117(c-Kit)，APC (Clone: ACK2) 流式抗体 (新品)
Human CD117/c-kit ELISA Kit检测试剂盒（酶联免疫吸附法）
KIT 分子靶点最新资讯

KIT 分子靶点信息概述

分子名：KIT, KIT proto-oncogene, receptor tyrosine kinase
基因家族：Receptor tyrosine kinases; CD molecules; Immunoglobulin like domain containing
别名：CD117; SCFR; C-Kit
曾用名：PBT
全称：mast/stem cell growth factor receptor Kit; piebald trait; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

KIT 分子靶点综述

CD117 也称为 c-Kit、Steel 因子受体和干细胞因子受体，这种酪氨酸激酶蛋白主要表达于造血祖细胞、肥大细胞、急性髓系白血病细胞(AML)。CD117 激活促进了这些细胞亚型的增殖和分化。缺乏或缺陷干细胞因子可导致造血祖细胞数量减少和严重贫血。CD117 也由黑色素细胞表达，并在这些细胞的信号传导和激活中起作用。

KIT, KIT proto-oncogene, receptor tyrosine kinase 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human KIT 分子靶点信息

分子名：KIT, KIT proto-oncogene, receptor tyrosine kinase
别称：
- C-Kit
- c-Kit protooncogene
- CD117
- KIT proto-oncogene receptor tyrosine kinase
- mast/stem cell growth factor receptor
- mast/stem cell growth factor receptor Kit
- MASTC
- p145 c-kit
- PBT
- piebald trait
- piebald trait protein
- proto-oncogene c-Kit
- proto-oncogene tyrosine-protein kinase Kit
- SCFR
- soluble KIT variant 1
- tyrosine-protein kinase Kit
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
基因序列：NCBI_Gene: 3815
蛋白序列：UniProtKB: P10721

人 Human KIT靶点分子功能（预测）

Enables cytokine binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of macromolecule metabolic process; and positive regulation of signal transduction. Located in extracellular space; fibrillar center; and plasma membrane. Implicated in several diseases, including acute myeloid leukemia; gastrointestinal stromal tumor; germ cell cancer (multiple); piebaldism; and renal cell carcinoma. Biomarker of several diseases, including Hirschsprung's disease; invasive ductal carcinoma; oxyphilic adenoma; reproductive organ cancer (multiple); and urinary system cancer (multiple).

小鼠 Mouse Kit 分子靶点信息

分子名：Kit, KIT proto-oncogene receptor tyrosine kinase
别称：
- belly-spot
- Bs
- c-KIT
- CD117
- dominant spotting
- Dominant white spotting
- Fdc
- gsf spotted coat 1
- gsf spotted coat 5
- Gsfsco1
- Gsfsco5
- Gsfsow3
- phenotype like Sl or W 3
- SCO1
- SCO5
- SOW3
- spotted sterile male
- Ssm
- Steel Factor Receptor
- Tr-kit
- W
基因序列：NCBI_Gene: 16590
蛋白序列：

小鼠 Mouse Kit 靶点分子功能（预测）

Enables SH2 domain binding activity; protease binding activity; and stem cell factor receptor activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; erythropoietin-mediated signaling pathway; and hemopoiesis. Acts upstream of or within several processes, including ectopic germ cell programmed cell death; hemopoiesis; and positive regulation of macromolecule metabolic process. Located in cell-cell junction and external side of plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo mesenchyme; and genitourinary system. Used to study gastrointestinal stromal tumor; macrocytic anemia; mastocytosis; and piebaldism. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; gastrointestinal stromal tumor; germ cell cancer (multiple); piebaldism; and renal cell carcinoma. Orthologous to human KIT (KIT proto-oncogene, receptor tyrosine kinase).

大鼠 Rat Kit 分子靶点信息

分子名：Kit, KIT proto-oncogene receptor tyrosine kinase
别称：
- c-kit receptor tyrosine kinase
- Kit oncogene
- mast/stem cell growth factor receptor
- mast/stem cell growth factor receptor Kit
- protein kinase
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
基因序列：NCBI_Gene: 64030
蛋白序列：

大鼠 Rat Kit 靶点分子功能（预测）

Enables protein tyrosine kinase activity. Involved in several processes, including gamete generation; positive regulation of gastro-intestinal system smooth muscle contraction; and protein phosphorylation. Located in acrosomal vesicle; cytoplasmic side of plasma membrane; and external side of plasma membrane. Used to study aplastic anemia and male infertility. Biomarker of acute pancreatitis and gastroschisis. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; gastrointestinal stromal tumor; germ cell cancer (multiple); piebaldism; and renal cell carcinoma. Orthologous to human KIT (KIT proto-oncogene, receptor tyrosine kinase).