文章目录[隐藏]
- IL1B 分子靶点信息概述
- IL1B 分子靶点综述
- IL1B, interleukin 1 beta 分子靶点种属信息
- IL1B 分子产品列表
- EasyGo!™ Rat IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
- EasyGo!™ Mouse IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
- Rat IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- Rat IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- Rat IL-1β High Sensitivity Standard (大鼠白细胞介素1β高敏 标准品)
- Rat IL-1β Standard (大鼠白细胞介素1β 标准品)
- Mouse IL-1β Standard (小鼠白介素1β 标准品)
- Mouse IL-1β High Sensitivity Standard (小鼠白细胞介素1β高敏 标准品)
- Mouse IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- Mouse IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- Human IL-1β Standard (人白介素1β 标准品)
- Human IL-1β High Sensitivity Standard (人白介素1β高敏 标准品)
- Human IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- Human IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- IL1B 分子靶点最新资讯
IL1B 分子靶点信息概述
- 分子名:IL1B, interleukin 1 beta
- 基因家族:Interleukins
- 别名:IL1F2; IL-1B; IL1-BETA
IL1B 分子靶点综述
白细胞介素1(IL-1)是17kDa的胞外多肽,分为IL-1α和IL-1β两种蛋白。IL-1β是活化的巨噬细胞分泌的蛋白前体,通过caspase1(CASP1/ICE)水解产生的活化形式。该细胞因子是炎症反应的重要介导者,参与许多细胞活性,包括细胞增殖、分化和凋亡。IL-1是一类重要的蛋白家族,它们由生物活化的单核细胞所衍生,参与炎症反应和免疫应答。IL-1β表达升高会产生各种不同的自身炎症综合征,最显著的是单基因条件称为CAPS,是由于触发IL-1β加工的炎性体受体NLRP3发生突变而引起的。本试剂盒用来检测人IL-1β的成熟形式和未裂解的前体形式。
IL1B, interleukin 1 beta 分子靶点种属信息
人 Human IL1B 分子靶点信息
- 分子名:IL1B, interleukin 1 beta
- 别称:
- catabolin
- IL-1
- IL-1 beta
- IL1-BETA
- IL1beta
- IL1F2
- interleukin 1, beta
- interleukin 1beta
- interleukin-1 beta
- preinterleukin 1 beta
- pro-interleukin-1-beta
- 基因序列:NCBI_Gene: 3553
- 蛋白序列:UniProtKB: P01584
人 Human IL1B靶点分子功能(预测)
Enables cytokine activity; integrin binding activity; and protein domain specific binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of nitrogen compound metabolic process; and regulation of signal transduction. Acts upstream of or within cellular response to organic substance and cellular response to xenobiotic stimulus. Located in extracellular space. Implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); bronchial disease (multiple); lung disease (multiple); and nose disease (multiple).
小鼠 Mouse Il1b 分子靶点信息
- 分子名:Il1b, interleukin 1 beta
- 别称:
- IL-1B
- Il-1b
- IL-1beta
- 基因序列:NCBI_Gene: 16176
- 蛋白序列:
小鼠 Mouse Il1b 靶点分子功能(预测)
Enables cytokine activity. Involved in several processes, including negative regulation of cell communication; regulation of defense response; and regulation of lipid metabolic process. Acts upstream of or within several processes, including ectopic germ cell programmed cell death; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Located in extracellular space and secretory granule. Is expressed in several structures, including dorsal aorta; early conceptus; hemolymphoid system; integument; and reproductive system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta).
大鼠 Rat Il1b 分子靶点信息
- 分子名:Il1b, interleukin 1 beta
- 别称:
- IL-1 beta
- IL-1F2
- interleukin-1 beta
- 基因序列:NCBI_Gene: 24494
- 蛋白序列:
大鼠 Rat Il1b 靶点分子功能(预测)
Enables cytokine activity. Involved in several processes, including positive regulation of intracellular signal transduction; regulation of gene expression; and regulation of neurogenesis. Located in extracellular space. Used to study several diseases, including artery disease (multiple); brain disease (multiple); glomerulonephritis (multiple); interstitial lung disease (multiple); and kidney failure (multiple). Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); brain disease (multiple); kidney failure (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); blood platelet disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Orthologous to human IL1B (interleukin 1 beta).
IL1B 分子产品列表
-
- EK301BEGA
- 一步法ELISA试剂盒
EasyGo!™ Rat IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
- ¥2,190.00 – ¥3,650.00
-
- EK201BEGA
- 一步法ELISA试剂盒
EasyGo!™ Mouse IL-1β One-Step ELISA Kit 检测试剂盒(酶联免疫吸附法)
- ¥2,190.00 – ¥3,650.00
-
- EK301B
- ELISA试剂盒
Rat IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥10,800.00
-
- EK301BHS
- ELISA试剂盒, 高敏试剂盒
Rat IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00
-
- EK301BHSS
- ELISA标准品, 高敏试剂盒
Rat IL-1β High Sensitivity Standard (大鼠白细胞介素1β高敏 标准品)
- ¥180.00
-
- EK301BS
- ELISA标准品
Rat IL-1β Standard (大鼠白细胞介素1β 标准品)
- ¥180.00
-
- EK201BS
- ELISA标准品
Mouse IL-1β Standard (小鼠白介素1β 标准品)
- ¥580.00
-
- EK201BHSS
- ELISA标准品, 高敏试剂盒
Mouse IL-1β High Sensitivity Standard (小鼠白细胞介素1β高敏 标准品)
- ¥180.00
-
- EK201BHS
- ELISA试剂盒, 高敏试剂盒
Mouse IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00
-
- EK201B
- ELISA试剂盒
Mouse IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥10,800.00
-
- EK101BS
- ELISA标准品
Human IL-1β Standard (人白介素1β 标准品)
- ¥180.00
-
- EK101BHSS
- ELISA标准品, 高敏试剂盒
Human IL-1β High Sensitivity Standard (人白介素1β高敏 标准品)
- ¥280.00
-
- EK101B
- ELISA试剂盒
Human IL-1β ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥10,800.00
-
- EK101BHS
- ELISA试剂盒, 高敏试剂盒
Human IL-1β High Sensitivity ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00