FCER2 靶点信息

FCER2 分子靶点信息概述

  • 分子名：FCER2, Fc epsilon receptor II
  • 基因家族：CD molecules; C-type lectin domain containing
  • 别名：CLEC4J; CD23; FCErII; FcepsilonRII
  • 曾用名：CD23A; FCE2
  • 全称：Fc epsilon RII; C-type lectin domain family 4 member J; Fc fragment of IgE, low affinity II, receptor for (CD23A); Fc fragment of IgE, low affinity II, receptor for (CD23); Fc fragment of IgE receptor II

FCER2 分子靶点综述

CD23 是一种 45kDa 的 II 型跨膜糖蛋白。CD23 是一种 II型膜蛋白，可由 B 细胞、单核细胞、巨噬细胞、嗜酸性粒细胞、血小板和树突状细胞表达。CD23 可介导巨噬细胞和嗜酸性粒细胞的 IgE 依赖性细胞毒性和吞噬作用。

FCER2, Fc epsilon receptor II 分子靶点种属信息

人 Human小鼠 Mouse大鼠 Rat

人 Human FCER2 分子靶点信息

  • 分子名：FCER2, Fc epsilon receptor II
  • 别称：
    • BLAST-2
    • C-type lectin domain family 4 member J
    • C-type lectin domain family 4, member J
    • CD23
    • CD23 antigen
    • CD23A
    • CLEC4J
    • Fc epsilon receptor II
    • Fc fragment of IgE, low affinity II, receptor for (CD23)
    • fc fragment of ige, low affinity ii, receptor for (cd23a)
    • fc-epsilon-RII
    • FCE2
    • IGEBF
    • immunoglobulin E-binding factor
    • immunoglobulin epsilon-chain
    • low affinity immunoglobulin epsilon Fc receptor
    • lymphocyte IgE receptor
  • 基因序列：NCBI_Gene: 2208
  • 蛋白序列：UniProtKB: P06734

人 Human FCER2靶点分子功能（预测）

Predicted to enable integrin binding activity. Involved in positive regulation of killing of cells of other organism; positive regulation of nitric-oxide synthase activity; and positive regulation of nitric-oxide synthase biosynthetic process. Located in extracellular exosome.

小鼠 Mouse Fcer2a 分子靶点信息

小鼠 Mouse Fcer2a 靶点分子功能（预测）

Predicted to enable carbohydrate binding activity. Acts upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin. Located in external side of plasma membrane. Orthologous to human FCER2 (Fc fragment of IgE receptor II).

大鼠 Rat Fcer2 分子靶点信息

  • 分子名：Fcer2, Fc epsilon receptor II
  • 别称：
    • CD23
    • Fc fragment of IgE, low affinity II, receptor for (CD23)
    • Fc receptor alpha multiple ligand receptor
    • Fc receptor alpha, multiple ligand receptor
    • Fc receptor, IgE, low affinity II, alpha polypeptide
    • Fcalpha muR
    • Fcalpha RII
    • Fcer2a
    • low affinity immunoglobulin epsilon Fc receptor
    • MGC93219
  • 基因序列：NCBI_Gene: 171075
  • 蛋白序列：

大鼠 Rat Fcer2 靶点分子功能（预测）

Predicted to enable carbohydrate binding activity. Predicted to be involved in positive regulation of killing of cells of other organism; positive regulation of nitric-oxide synthase activity; and positive regulation of nitric-oxide synthase biosynthetic process. Predicted to act upstream of or within positive regulation of humoral immune response mediated by circulating immunoglobulin. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human FCER2 (Fc fragment of IgE receptor II).

FCER2 分子产品列表

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