文章目录[隐藏]
- ADIPOQ 分子靶点信息概述
- ADIPOQ 分子靶点综述
- ADIPOQ, adiponectin, C1Q and collagen domain containing 分子靶点种属信息
- ADIPOQ 分子产品列表
- Rat Adiponectin/Acrp30 ELISA Kit检测试剂盒(酶联免疫吸附法)
- Rat Adiponectin/Acrp30 Standard (大鼠脂联素 (Adiponectin/Acrp30) 标准品)
- Mouse Adiponectin ELISA Kit检测试剂盒(酶联免疫吸附法)
- Mouse Adiponectin/Acrp30 Standard (小鼠Adiponectin/Acrp30 标准品)
- Human Adiponectin/Acrp30 Standard (人脂联素 标准品)
- Human Adiponectin ELISA Kit检测试剂盒(酶联免疫吸附法)
- ADIPOQ 分子靶点最新资讯
ADIPOQ 分子靶点信息概述
- 分子名:ADIPOQ, adiponectin, C1Q and collagen domain containing
- 基因家族:C1q and TNF related
- 别名:ACRP30; apM1; GBP28; adiponectin
- 曾用名:ACDC
- 全称:adipose most abundant gene transcript 1; adiponectin precursor; adipocyte, C1Q and collagen domain containing
ADIPOQ 分子靶点综述
脂联素,又称脂肪细胞补体相关蛋白30(Acrp30),参与调节葡萄糖水平和脂肪酸分解。它组装成不同的复合物包括三聚体、六聚体和高阶寡聚体结构,进而可能影响生物活性。脂联素是一种蛋白质激素,调节许多代谢过程,包括葡萄糖调节和脂肪酸氧化。脂肪组织(以及妊娠期的胎盘)专门分泌脂联素到血液中,因此相对于其它许多激素,血浆中的脂联素含量很丰富。脂联素可能具有抗动脉粥样硬化和消炎的作用,可负向调节粒单祖细胞的生长和TNF-α在巨噬细胞中的产生。监测一些病理状态下的血清脂联素水平,如2型糖尿病、肥胖、动脉粥样硬化和非酒精性脂肪肝疾病,可为我们了解脂联素提供更详细的见解。
ADIPOQ, adiponectin, C1Q and collagen domain containing 分子靶点种属信息
人 Human ADIPOQ 分子靶点信息
- 分子名:ADIPOQ, adiponectin, C1Q and collagen domain containing
- 别称:
- 30 kDa adipocyte complement-related protein
- ACDC
- ACRP30
- adipocyte complement-related 30 kDa protein
- adiponectin
- adipose most abundant gene transcript 1 protein
- adipose specific collagen-like factor
- ADIPQTL1
- ADPN
- APM-1
- APM1
- GBP28
- gelatin-binding protein 28
- 基因序列:NCBI_Gene: 9370
- 蛋白序列:UniProtKB: Q15848
人 Human ADIPOQ靶点分子功能(预测)
Enables hormone activity; protein homodimerization activity; and sialic acid binding activity. Involved in several processes, including negative regulation of cell communication; negative regulation of cell differentiation; and negative regulation of macromolecule metabolic process. Located in cell surface and extracellular space. Part of collagen-containing extracellular matrix. Implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Biomarker of several diseases, including autoimmune disease (multiple); cardiovascular system disease (multiple); diabetes mellitus (multiple); fatty liver disease (multiple); and inflammatory bowel disease (multiple).
小鼠 Mouse Adipoq 分子靶点信息
- 分子名:Adipoq, adiponectin, C1Q and collagen domain containing
- 别称:
- Acdc
- Acrp30
- Ad
- adipo
- adipocyte complement related protein
- adipocyte, C1Q and collagen domain containing
- adiponectin
- apM1
- APN
- GBP28
- 基因序列:NCBI_Gene: 11450
- 蛋白序列:
小鼠 Mouse Adipoq 靶点分子功能(预测)
Enables hormone activity and identical protein binding activity. Involved in several processes, including detection of oxidative stress; negative regulation of cold-induced thermogenesis; and regulation of protein serine/threonine kinase activity. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including brown fat cell differentiation; negative regulation of gluconeogenesis; and positive regulation of glucose import. Located in endoplasmic reticulum and extracellular space. Is expressed in several structures, including adipose tissue; axial musculature; gut; male reproductive gland or organ; and serum. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing).
大鼠 Rat Adipoq 分子靶点信息
- 分子名:Adipoq, adiponectin, C1Q and collagen domain containing
- 别称:
- Acdc
- Acrp30
- Adid
- adipocyte complement related protein of 30 kDa
- adiponectin
- adiponectin d
- 基因序列:NCBI_Gene: 246253
- 蛋白序列:
大鼠 Rat Adipoq 靶点分子功能(预测)
Enables identical protein binding activity. Involved in several processes, including cellular response to organonitrogen compound; positive regulation of glycogen (starch) synthase activity; and positive regulation of protein phosphorylation. Located in extracellular space. Part of protein-containing complex. Used to study brain infarction. Biomarker of several diseases, including end stage renal disease; fatty liver disease (multiple); glucose metabolism disease (multiple); hyperthyroidism; and obesity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collagen domain containing).
ADIPOQ 分子产品列表
-
- EK395
- ELISA试剂盒
Rat Adiponectin/Acrp30 ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥2,000.00 – ¥3,400.00
-
- EK295
- ELISA试剂盒
Mouse Adiponectin ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00
-
- EK195S
- ELISA标准品
Human Adiponectin/Acrp30 Standard (人脂联素 标准品)
- ¥280.00
-
- EK195
- ELISA试剂盒
Human Adiponectin ELISA Kit检测试剂盒(酶联免疫吸附法)
- ¥1,600.00 – ¥2,650.00